李少英

【摘要】目的：研究复方甘草酸苷治疗慢性湿疹临床疗效。方法：选取2015年4月-2016年4月期间收治的102例慢性湿疹患者进行临床研究，将患者进行随机分组，分别分成对照组和实验组各51例。其中对照组采用为患者口服米咪唑斯汀片的方式，同时联合使用复方地塞米松软膏进行外敷治疗。实验组在这一基础上，为患者使用复方甘草酸苷片进行治疗，对比两组患者临床疗效。结果：试验组治疗总有效率为96.07%，对照组治疗总有效率为70.587%。同时，实验组患者中，显效20例，有效29例，无效2例。对照组，显效16例，有效20，无效11例。两组患者经过治疗后，临床疗效差异显著（p<0.05）。结论：针对慢性湿疹患者，进行常规治疗的基础上，使用复方甘草酸苷进行治疗，能够有效减少患者不良反应发生率，同时具有显著临床疗效，值得广泛应用并进一步推广。

【关键词】复方甘草酸苷；慢性湿疹；临床疗效

[Abstract] Objective：To study the clinical efficacy of Compound Glycyrrhizin in the treatment of chronic eczema. Methods：a total of 102 patients with chronic eczema were selected from April 2015 to April -2016 for clinical study. The patients were randomly divided into two groups： the control group and the experimental group， each with 51 cases. The control group was treated with oral mizolastine tablets and combined with Compound Dexamethasone Acetate Ointment for external application. On the basis of the experimental group， the patients were treated with Compound Glycyrrhizin Tablets， and the clinical efficacy of the two groups was compared. Results：the total effective rate of the experimental group was 96.07%， and the total effective rate of the control group was 70.587%. At the same time， in the experimental group， 20 cases were markedly effective， 29 cases were effective， and 2 cases were ineffective. In the control group， 16 cases were markedly effective， effective 20， ineffective in 11 cases. Two groups of patients after treatment， the clinical efficacy of the difference was significant （P < 0.05）. Conclusion：for patients with chronic eczema patients， based on conventional therapy， the use of Compound Glycyrrhizin treatment， can effectively reduce the incidence of adverse reactions in patients， and has significant clinical effect， it is worthy of wide application and further promotion.

[Key words] compound glycyrrhizin； chronic eczema； clinical efficacy

【中圖分类号】R758.2 【文献标识码】A 【文章编号】2095-6851（2017）07-00-01

引言：

慢性湿疹属于皮肤疾患当中的一项十分常见的疾病，引发这一疾病的内外因较多，导致患者真皮浅层和表层出现炎性反应，这一疾病经常复发，临床上治疗比较困难。慢性湿疹分为急性、亚急性和慢性，疾病发病初始并不明显，患者经常抓挠或者摩擦等，导致其受到刺激，从而形成慢性湿疹。本院选取2015年4月-2016年4月期间收治的102例慢性湿疹患者进行临床研究，现报道如下。

1.资料与方法

1.1 一般资料

选取2015年4月-2016年4月期间收治的102例慢性湿疹患者进行临床研究，将患者进行随机分组，分别分成对照组和实验组各51例。所选患者全部符合《皮肤性病学》第六版中慢性湿疹诊断标准。实验组当中，男性26例，女性25例，患者年龄在20-56岁之间，平均年龄为（36±2.5）岁之间，病程在6个月-20年之间，平均病程在（9.5±2.3）年。……