张翠兰

【摘 要】目的：观察分析甲硝唑栓联合干扰素治疗慢性宫颈炎的临床疗效。方法：将84例慢性宫颈炎患者采用随机数字法分为对照组42例和观察组42例，对照组采用甲硝唑栓治疗，观察组在对照组的基础上增加使用干扰素，比较两组治疗有效率及复发率。结果：观察组总有效率92.8%，明显高于对照组73.8%（P<0.05），差异具有统计学意义；观察组复发率低于对照组。结论：甲硝唑栓联合干扰素治疗慢性宫颈炎疗效显著，复发率低，安全可靠，在临床上值得应用及推广。

【关键词】甲硝唑栓；干扰素；慢性宫颈炎；临床疗效

【中图分类号】R271.13 【文献标志码】A【文章编号】1007-8517（2016）15-0114-02

Abstract：Objective To observe and analyze the clinical effects of metronidazole suppositories combined with interferon in the treatment of chronic cervicitis.Methods 84 patients with chronic cervicitis and who accepted treatments in our hospital from February， 2014 to February， 2015 were selected， and these patients were randomly divided into the control group of 42 cases and the observation group of 42 cases by the random number method. In the control group， they were treated with the metronidazole suppositories while in the observation group， on the basis of the treatment in the control group， they were treated with the interferon. Then， the treatment effective rate and recurrence rateof the two groups of patients were compared.Results The total effective rate in the observation group was 92.8% which was higher than that in the control group of 73.8% （P<0.05）， the difference was statistically significant；The recurrence rate in the observation group was lower than that of the control group.Conclusion The clinical effects of metronidazole suppositories combined with interferon in the treatment of chronic cervicitis are significant， which the recurrence rate is low and safety and reliable， it is worthy to be applied and promoted in the clinical.

Keywords：Metronidazole Suppositories； Interferon； Chronic Cervicitis； Clinical Effect

慢性宫颈炎是临床常见的慢性妇科疾病，多数因为急性宫颈炎导致[1]。育龄期妇女发病率高，临床症状表现为腹部疼痛、白带异常等，若不及时治疗，可能出现宫颈糜烂，不孕不育、输卵管炎，甚至引发宫颈癌，严重危害患者的身心健康[2]。目前对慢性宫颈炎的治疗方法有物理治疗、药物治疗、免疫治疗三种方法。本文探析甲硝唑栓联合干扰素治疗慢性宫颈炎的临床疗效，对本院采用不同方法治疗慢性宫颈炎的患者的治疗效果进行分析对比，现报道如下。

1 资料与方法

1.1 一般资料 将我院2014年2月至2015年2月收治的84例慢性宫颈炎患者，采用随机数字法分为对照组42例和观察组42例，对照组年龄22～45岁，平均年龄（38.3±8.5）岁，宫颈炎按三级划分：Ⅰ级14例，Ⅱ级21例，Ⅲ级7例，糜烂类型有：单纯型19例，颗粒型13例，乳头型10例。观察组年龄23～48岁，平均年龄（39.5±9.2）岁，宫颈炎按三级划分：Ⅰ级13例，Ⅱ级20例，Ⅲ级9例，糜烂类型有：单纯型17例，颗粒型14例，乳头型11例。两组患者上述一般资料比较，差异没有统计学意义（P>0.05），具有可比性。纳入标准：患者经过妇科检查确诊为宫颈炎；患……