血清C反应蛋白、纤维蛋白原、脂蛋白（a）在急性脑梗塞诊断中应用价值研究

2016-09-05张瑾施俊峰江苏省宜兴市人民医院神经内科江苏宜兴214200

中外医疗 2016年11期

张瑾，施俊峰江苏省宜兴市人民医院神经内科，江苏宜兴 214200

张瑾，施俊峰
江苏省宜兴市人民医院神经内科，江苏宜兴 214200

目的探析血清C反应蛋白、纤维蛋白原、脂蛋白（a）在急性脑梗塞诊断中价值。方法选取该院2013年1月—2015年8月收治的30例急性脑梗塞患者，作为研究组，对照组选择同期来该院体检的健康志愿者30例，检测两组CRP、FG及LP（a）水平，比较分析其与梗塞严重程度之间关系。结果研究组CRP、FG及LP（a）水平为（14.8±2.1）mg/L、（8.3±3.2）g/L、（324.1±5.4）mg/L与对照组比较差异有统计学意义（P＜0.05）；轻型的患者CRP、FG及LP（a）水平（7.6± 1.2）mg/L、（5.1±0.3）g/L、（275.4±4.3）mg/L低于中型及重型的患者，P＜0.05；中型患者CRP、FG及LP（a）水平（14.3±2.1）mg/L、（8.2±2.5）g/L、（335.8±4.4）mg/L与重型比较差异有统计学意义（P＜0.05）。结论对于急性脑梗塞患者检测CRP、FG及LP（a）水平，能够显示患者梗塞的程度，可作为诊断的依据，应用价值较好。

急性脑梗塞；CRP；FG；LP（a）

［Abstract］Objective To discuss and analyze the value of serum C-reactive protein，contractinogen and lipoprotein （a）in diagnosis of acute cerebral infarction.Methods 30 cases of patients with acute cerebral infarction admitted and treated in our hospital from January 2013 to August 2015 were selected as the research group，30 cases of healthy volunteers with physical examination in our hospital at the same period were selected as the control group，the CRP，FG and LP （a）levels of the two groups were detected，and the correlation between them and the infarction severity was comparatively analyzed.Results The CRP，FG and LP（a）levels were respectively（14.8±2.1）mg/L，（8.3±3.2）g/L and（324.1±5.4）mg/L in the research group，which were obviously different from those in the control group（P＜0.05），the CRP，FG and LP（a）levels were （7.6±1.2）mg/L，（5.1±0.3）g/L and（275.4±4.3）mg/L in the mild patients，which were lower than those in the moderate and severe patients，the CRP，FG and LP（a）levels of moderate patients were respectively（14.3±2.1）mg/L，（8.2±2.5）g/L，and （335.8±4.4）mg/L，and there were differences in the CRP，FG and LP（a）levels between the moderate patients and the severe patients（P＜0.05）.Conclusion The detection of CRP，FG and LP（a）levels of patients with acute cerebral infarction can show the degree of infarction of patients，which can be used as the basis for diagnosis，and the application value is better.

［Key words］Acute cerebral infarction；CRP；FG；LP（a）

临床上急性脑梗塞是较为常见的疾病，CT检查能够对脑梗塞病灶情况进行早期诊断。相关研究指出［1］，早期诊断中病变位置在脑干和小脑处，CT诊断可能误诊。也有学者提出［2］，早期检测血清CRP、FG及LP（a）水平，观察其改变情况和脑血管事件的发生具有紧密的相关性，为探析血清CRP、FG及LP（a）在急性脑梗塞诊断中价值，该研究将2013年1月—2015年8月收治的30例急性脑梗塞患者，作为该次研究对象，现报道如下。