刘开云扬州市第一人民医院儿科，江苏扬州 225001

红霉素联合阿奇霉素序贯疗法在小儿支原体肺炎治疗中的应用价值探讨

刘开云
扬州市第一人民医院儿科，江苏扬州 225001

目的分析红霉素联合阿奇霉素序贯疗法在小儿支原体肺炎治疗中的应用价值。 方法该研究中选取60例小儿支原体肺炎患者作为观察对象，分组形式为随机数字分组法。研究组30例采用红霉素联合阿奇霉素序贯疗法，参照组30例给予红霉素治疗，对两组患者的临床疗效和不良反应进行观察，记录症状消失时间和住院时间。结果研究组的有效率为93.33%，高于参照组的73.33%（P＜0.05）；研究组不良反应发生率为6.67%，低于参照组的26.67%（P＜0.05）；研究组症状消失时间和住院时间明显短于参照组，两组比较具有明显的差异（P＜0.05）。 结论小儿支原体肺炎利用红霉素联合阿奇霉素序贯疗法具有很高的疗效，不良反应较少。

小儿支原体肺炎；红霉素；阿奇霉素；序贯疗法

［Abstract］Objective To analyze the application value of erythromycin combined with zaithromycin sequential therapy in treatment of mycoplasma pneumonia in children.Methods 60 cases of children with zaithromycin sequential therapy were selected as the research objects and randomly divided into two groups with 30 cases in each，the research group were treated with erythromycin combined with zaithromycin sequential therapy，the control group were treated with erythromycin，and the clinical curative effects and adverse reactions of the two groups were observed，and the symptom disappearance time and length of stay were recorded.Results The effective rate in the research group was higher than that in the control group，（6.67%vs 26.67%）（P＜0.05），the symptom disappearance time and length of stay in the research group were obviously shorter than those in the control group，and there were obvious differences between groups by comparison（P＜0.05）.Conclusion The curative effect of erythromycin combined with zaithromycin sequential therapy in treatment of mycoplasma pneumonia in children is extremely high with fewer adverse reactions.

［Key words］Mycoplasma pneumonia in children；Erythromycin；Azithromycin；Sequential therapy

小儿支原体肺炎是一种常见的呼吸系统疾病，是由支原体感染而引起的以顽固性剧烈咳嗽为临床主要表现的肺部炎症，一般潜伏期为2～3周不等，多发生于5～15岁的儿童，在发病初期患儿会出现咳嗽、咽喉痛等临床症状［1-2］。红霉素是临床常见药物，适用于链球菌引起的扁桃体炎、流感杆菌引起的上呼吸道感染、肺炎链球菌下呼吸道感染，目前，红霉素联合阿奇霉素序贯疗法是治疗小儿支原体肺炎常用的方法，为了探讨其效果和安全性，该院对2014年11月—2015年11月期间60例小儿支原体肺炎患者采用了两种不同方式治疗，比较两者的疗效，现报道如下。……