崔焕波吉林省公安边防总队医院检验科，吉林长春 130051

降钙素原电化学发光法与胶体免疫层析法检验结果比较分析

崔焕波
吉林省公安边防总队医院检验科，吉林长春 130051

目的研究对比降钙素原电化学发光法与胶体免疫层析法的临床检验结果，为临床检测提供科学依据。 方法随机选取该院2014年3月—2015年10月收治的70例住院患者，随机分成两组。35例为对照组，应用降钙素原电化学发光法定量检验；35例为观察组，采用降钙素原胶体免疫层析法进行定性检验。统计比较两组患者的临床检验结果。结果 观察组患者中，检验结果为阳性（降钙素原浓度＞0.5 ng/L）的有35例（100%），明显高于对照组患者的29例（82.86%），差异具有统计学意义（P＜0.05）。结论降钙素原电化学发光检测法灵敏度好，阳性检出率更高；降钙素原胶体免疫层析检测法检验时间短、简单快速。临床检测中，应根据两种检测方式的不同特点合理加以选择和应用，有助于细菌感染性疾病的早期准确诊断。

降钙素原；电化学发光法；胶体免疫层析法；临床检验结果

［Abstract］Objective To research and compare the clinical test results of procalcitonin electro chemical luminescence and colloid immunochromatographic test strip and provide scientific basis for clinical detection.Methods 70 cases of inpatients admitted and treated in our hospital from March 2014 to October 2015 were selected and randomly divided into two groups with 35 cases in each，the control group adopted procalcitonin electro chemical luminescence for quantitative test，the observation group adopted colloid immunochromatographic test strip for qualitative test，and the clinical test results of the two groups were counted and compared.Results 35 cases（100%）were with positive test results （procalcitonin concentration＞0.5ng/L），which were obviously higher than those in the control group（29 cases）（82.86%），and the difference had statistical significance（P＜0.05）.Conclusion Procalcitonin electro chemical luminescence has a good sensitivity degree and the positive detection rate is higher，and procalcitonin colloid immunochromatographic test strip has short test time and it is easy and rapid，and we should rationally select and apply them according to the different characteristics of the two detection Methods in clinical detection，which contributes to the early accurate diagnosis of bacterial infectious diseases.

［Key words］Procalcitonin；Electro chemical luminescence；Colloid immunochromatographic test strip；Clinical test results

降钙素原是人体内部的一种蛋白质，一旦患者遭受到比较严重的细菌、寄生虫或者病毒感染后，血清中的降钙素原含量会急速升高，可以作为诊断和监测细菌炎性疾病的重要依据［1］。目前临床中主要是通过电化学发光法与胶体免疫层析法两种方式检验，其中电化学发光法是最先进的标记免疫检测技术，能够在较短时间内快速分析出结果，效果十分显著。……