脂肪分解和仿生物电刺激治疗对超重和肥胖的多囊卵巢综合征患者内分泌及代谢的影响
2016-08-03何茜冬唐妍苏园园韩燕华陈燕蔡彬
何茜冬+唐妍+苏园园+韩燕华+陈燕+蔡彬媚

【摘要】 目的 探讨脂肪分解和仿生物电刺激治疗对超重和肥胖的多囊卵巢综合征(PCOS)患者血清学指标的影响。方法 81例体质量指数(BMI)≥23 kg/m2的PCOS患者, 按患者意愿分为观察组(57例)和对照组(24例)。观察组给予脂肪分解和仿生物电刺激治疗, 对照组仅宣教进行生活方式干预。观察两组各血清学指标的差异。结果 观察组治疗后空腹血糖(FPG)和空腹胰岛素(FIN)水平较治疗前降低(P<0.05)。对照组治疗前后各指标差异无统计学意义(P>0.05)。结论 脂肪分解和仿生物电刺激治疗可降低超重和肥胖的PCOS患者血清FPG和FIN水平。
【关键词】 脂肪分解;仿生物电刺激;超重;肥胖;多囊卵巢综合征
DOI:10.14163/j.cnki.11-5547/r.2016.18.015
【Abstract】 Objective To investigate influence by lipolysis and bionic electrical stimulation treatment on serological indicators in polycystic ovarian syndrome (PCOS) patients with overweight and obesity. Methods A total of 81 PCOS patients with body mass index (BMI) ≥23 kg/m2 were divided by their willingness into observation group (57 cases) and control group (24 cases). The observation group received lipolysis and bionic electrical stimulation treatment, and the control group received only lifestyle intervention education. Serological indicators were observed in the two groups. Results The observation group had lower fasting plasma glucose (FPG) and fasting insulin (FIN) levels after treatment than those before treatment (P<0.05). Differences of indexes in the control group had no statistical significance before and after treatment (P>0.05). Conclusion Treatment by lipolysis and bionic electrical stimulation can decrease serum FPG and FIN levels in PCOS patients with overweight and obesity.
【Key words】 Lipolysis; Bionic electrical stimulation; Overweight; Obesity; Polycystic ovarian syndrome
超重或肥胖是PCOS常见的临床特征, 影响着约50%的PCOS患者。减轻体重、减少脂肪组织含量, 可改善生殖和代谢的异常。本文探讨脂肪分解和仿生物电刺激治疗对超重和肥胖的PCOS患者血清学指标的影响, 现报告如下。
1 资料与方法
1. 1 一般资料 收集2012年9月~2014年12月在本院专科门诊就诊的超重和肥胖(BMI ≥23 kg/m2)型PCOS患者81例, 按患者意愿分成观察组(57例)和对照组(24例), 签署知情同意书。PCOS的诊断标准采用2003年鹿特丹标准。所有患者均无合并肝肾疾病、心脏病、糖尿病等内科疾病, 近3个月无激素使用史。
1. 2 治疗方法 观察组:在宣教进行生活方式干预的基础上, 于月经干净后给予脂肪分解和仿生物电刺激治疗。每2~3天1次, 2次/周。治疗后3 d内阴道超声确定双侧卵巢基础状态后再次测定记录上述测量学和血清学指标。具体治疗方法为:使用PHENIX PLUS(ML36)治疗仪(广州市杉山医疗器械有限公司)的脂肪分解和仿生物电刺激模式:开放36个脂肪分解通道, 脂肪分解电流脉冲宽度320 μs, 频率30 Hz, 最大电流强度100 mA, 波形恒定。……
