卢仕仰 黄从付 刘巧红

[摘要] 目的 探讨头孢他定钠联合阿奇霉素治疗小儿肺炎支原体肺炎的临床效果。 方法 选择我院2013年1月1日～2014年5月1日收治的126例小儿肺炎支原体肺炎患儿作为研究对象。将患儿随机分为干预组、对照组，每组63例。对照组给予阿奇霉素治疗，干预组在对照组基础上给予头孢他定钠治疗。 结果 干预组的总有效率明显高于对照组（P<0.05）。干预组的临床症状（发热、咳嗽、肺部啰音、喘息）消失时间明显短于对照组（P<0.05）。干预组的不良反应发生率明显低于对照组（P<0.05）。 结论 头孢他定钠联合阿奇霉素治疗小儿肺炎支原体肺炎能有效提高临床效果，改善患者的临床症状，加快其病情恢复，降低不良反应发生率。

[关键词] 小儿肺炎支原体肺炎；头孢他定钠；阿奇霉素；临床症状；不良反应

[中图分类号] R725.6 [文献标识码] A [文章编号] 1674-4721（2016）02（b）-0059-03

Clinical effect of ceftazidime sodium combined with azithromycin treating Mycoplasma pneumoniae pneumonia in children

LU Shi-yang HUANG Cong-fu LIU Qiao-hong

Department of Emergency，Maternal and Child Health Hospital of Longgang District in Shenzhen City，Shenzhen 518000，China

[Abstract] Objective To observe the clinical effect of ceftazidime sodium combined with azithromycin treating Mycoplasma pneumoniae pneumonia in children. Methods 126 children Mycoplasma pneumoniae pneumonia received by our hospital from January 1，2013 to May 1，2015 were selected as study group.126 patients were divided into intervention group and control group，and there were 63 cases in each group.Control group was treated by azithromycin，while intervention group was treated by ceftazidime sodium on the basis of control group. Results The total effective rate of intervention group was significantly higher than that of control group （P<0.05）.The disappeared time of clinical symptoms （fever，cough，pulmonary rales，wheezing） in intervention group） was obviously shorter than that of control group （P<0.05）.The incidence rate of adverse reaction in intervention group was significantly lower than that o control group （P<0.05）. Conclusion Ceftazidime sodium combined with azithromycin treating Mycoplasma pneumoniae pneumonia in children can effectively improve the clinical effect，improve the clinical symptoms of patients，accelerate the recovery of the disease，reduce the incidence rate of adverse reaction.

[Key words] Mycoplasma pneumoniae pneumonia in children；Ceftazidime sodium；Azithromycin；Clinical symptom；Adverse reaction

目前，小儿肺炎支原体肺炎是儿童常见的一种肺炎，病原为肺炎支原体，咳嗽是其的主要特征。对于小儿肺炎支原体肺炎的治疗除一般治疗外，给予对症处理，如祛痰、止喘、应用抗生素等，但是长时间应用抗生素会出现抗药性，效果并不显著[1]。有研究发现，头孢他定钠联合阿奇霉素治疗小儿肺炎支原体肺炎的效果较好[2-3]。本研究为探讨头孢他定钠联合阿奇霉素治疗小儿肺炎支原体肺炎的临床效果，我院选取126例小儿肺炎支原体肺炎患儿进行研究，现报告如下。

1 资料与方法

1.1 一般资料

选取我院2013年1月1日～2014年5月1日收治的126例小儿肺炎支原体肺炎患儿为研究对象。以上患者均自愿参加本研究，并签署相关协议。排除先天性心脏病患者。将126例患儿随机分为对照组、干预组，每组63例。对照组：29例为女性，34例为男性，年龄为8个月～11岁，平均（5.35±2.46）岁，病程为3～13 d，平均（4.24±2.43）d，患儿的临床表现有咳嗽、发热等；干预组：28例为女性，35例为男性，年龄为1～12岁，平均（4.63±2.63）岁，病程为3～13 d，平均（4.45±6.32）d，患儿的临床表现有咳嗽、发热等。……