林大勇

[摘要] 目的 观察经无创呼吸机治疗慢性阻塞性肺疾病合并呼吸衰竭患者的临床效果。 方法 随机抽取112例我院于2012年1月～2014年12月收治的慢性阻塞性肺疾病合并呼吸衰竭患者进行研究，根据其入院顺序随机分为对照组（56例，经常规治疗）和观察组（56例，经无创呼吸机治疗），评价两组患者的临床效果、治疗前后的血气和临床症状变化，统计其并发症发生情况。 结果 ①观察组的总有效率为91.07%（51例），明显高于对照组的67.86%（38例）（P<0.05）；观察组并发症发生率为3.57%（2例），明显低于对照组的28.57%（16例）（P<0.05）。②经治疗，两组患者的PaCO2、PaO2、SaO2、RR、HR均明显改善，且观察组的上述指标均优于对照组，各项指标治疗前后的组内比较和治疗后的组间比较，差异有统计学意义（P<0.05）。 结论 慢性阻塞性肺疾病合并呼吸衰竭患者经无创呼吸机治疗具有显著的临床效果，可有效预防并发症的发生，迅速缓解其临床症状，改善其血气指标，具有较高的临床应用价值。

[关键词] 慢性阻塞性肺疾病；呼吸衰竭；无创呼吸机；临床效果

[中图分类号] R563 [文献标识码] A [文章编号] 1674-4721（2016）02（b）-0041-03

Clinical effects observation of noninvasive ventilator in treating chronic obstructive pulmonary disease with respiratory failure

LIN Da-yong

Department of Respiratory Medicine，Tiefa Coal Group General Hospital of Diaobingshan City in Liaoning Province，Diaobingshan 112700，China

[Abstract] Objective To observe the clinical effects of noninvasive ventilator in treating chronic obstructive pulmonary disease with respiratory failure. Methods 112 patients with chronic obstructive pulmonary disease with respiratory failure from January 2012 to December 2014 of our hospital were randomly selected and were randomly divided into control group （n=56，They were given routine treatment） and observation group（n=56，They were given noninvasive ventilator treatment） according to their admitted order.Clinical effects，blood gas and changes of clinical symptoms before and after treatment in two groups were evaluated.The incidence of complications were counted. Results ①The total effective rate in observation group was 91.07%（n=51），obvious higher than that was 67.87% in control group（n=38）（P<0.05）.The complication rate of the observation group was 3.57%（n=2），which was significantly lower than 28.57% in the control group（n=16）.Both of total effective rate and incidence rate of complications between two groups had obvious difference，and the difference was statistical significance（P<0.05）.②After treatment，all of PaCO2，PaO2，SaO2，RR and HR in two groups was improved obvious respectively，and the index in observation group was better than that of control group respectively.The comparison in the group of all index before and after treatment and inter-group difference after treatment had statistical significance（P<0.05）. Conclusion Using noninvasive ventilator for chronic obstructive pulmonary disease with respiratory failure patients has obvious clinical effects.It can effective prevent the incidence of complications，relief clinical symptoms speed and improve blood gas index.It has higher clinical application value.

[Key words] Chronic obstructive pulmonary disease；Respiratory failure；Noninvasive ventilator；Clinical effects

目前，随着环境问题的日益突出，加上人们日常生活习惯的转变，慢性阻塞性肺疾病的发生率不断升高，成为呼吸系统疾病临床诊疗中的一种常见肺部病变，并以持续性的气流流通受阻为最主要的临床症状，导致患者肺部通气功能异常，具有较高的病死率[1-3]。随着慢性阻塞性肺部疾病的持续发展，患者的气道阻塞程度会不断加深，导致其呼吸越来越困难，最终发展为呼吸衰竭。目前，无创呼吸机在慢性阻塞性肺部疾病合并呼吸衰竭的临床治疗中被广泛应用，主要是因为其可以明显改善患者气道的通气状况，减小气道阻力，促进肺部功能改善[4-6]。本文旨在研究慢性阻塞性肺疾病合并呼吸衰竭患者经无创呼吸机治疗的临床效果。

1 资料与方法

1.1 一般资料

从我院2012年1月～2014年12月收治的慢性阻塞性肺疾病合并呼吸衰竭患者中随机选取112例进行研究。……