刘芳

[摘要] 目的 探讨妊娠期糖尿病（GDM）规范化治疗对妊娠结局的影响。方法 回顾性分析2009年10月～2013年10月入住我院的100例GDM患者的临床资料，将其按照奇偶数字法随机地分为对照组与观察组，每组50例。对照组行保守治疗，观察组予规范化治疗。比较两组显性糖尿病发病率、妊娠相关情况及围生儿结局等。结果 对照组显性糖尿病患者11例（占22.00%），观察组显性糖尿病患者3例（占6.00%），两组差异具有统计学意义（P＜0.05）；观察组妊高征、剖宫产、羊水过多、早产及孕期感染发生率均显著低于对照组（P＜0.05）；观察组巨大儿、胎儿生长萎缩（胎儿生长受限）、胎儿畸形、新生儿呼吸窘迫综合征以及新生儿低血糖发病率均显著低于对照组（P＜0.05）。结论 加强GDM规范化治疗，能够有效改善妊娠结局，应在临床上加以推广及应用。

[关键词] 妊娠期糖尿病；规范化治疗；妊娠结局；影响

[中图分类号] R714.256[文献标识码] B[文章编号] 1673-9701（2014）19-0155-02

Analysis and research of standardized treatment of gestational diabetes on pregnancy outcomes

LIU Fang

ShandongProvinceZibo City Central Hospital，Zibo 255036，China

[Abstract] Objective To investigate the impact on pregnancy outcome for standardizedtreatment of GDM. Methods100 cases GDM patients were randomly divided into control group and observation group，each 50 cases. The control groupwasgiven conservative treatment， observation group was given standard treatment.The incidence of overt diabetes，pregnancy-related conditions and perinatal outcome were compared. Results After treatment， the number of patients with overt diabetic control group of 11 cases（22.00%）， the number of patients with overt diabetic group 3 patients in the observation group（6.00%）（P <0.05）; observation group pregnancy-induced hypertension，cesarean section，polyhydramnios，premature birth and infection during pregnancy were significantly lower than the control group（P<0.05）; huge children，fetal growth and contraction，fetal malformations，neonatal respiratory distress syndrome and neonatal hypoglycemia incidence rates of observation group were significantly lower than the control group. Conclusion Strengthening GDM standardized treatment can effectively improve pregnancy outcomes.

[Key words] Gestational diabetes; Standardized treatment; Pregnancy outcomes; Impact

妊娠糖尿病（GDM）指的是妊娠期首次或者多次发现出现不同程度的糖耐量代谢异常。GDM能够在一定程度上对孕期孕妇以及围生期新生儿的生长质量产生影响，该病患者主要表现包括[1-2]：巨大儿、胎儿生长发育萎缩或停滞（胎儿生长受限）、畸形儿、胎死腹中（胎死宫内）、新生儿呼吸窘迫征以及新生儿低血糖等，孕妇围生产期妊高征（孕妇妊高征）、羊水过多、胎膜早破、雌激素以及孕激素水平增高而引起糖代谢速度显著增强，剖宫产率等明显增加[3]。为了能够有效降低妊娠期糖尿病的发病率，本研究主要采用了GDM规范化治疗，现报道如下。……