袁建华

[摘要] 目的 分析新生儿窒息与胎儿羊水污染的关系。 方法 选择在我院进行分娩的新生儿618例为研究对象，比较羊水无污染以及不同污染程度胎儿胎心电图异常情况、新生儿发生窒息的情况。结果 羊水污染胎儿胎心监护异常率显著高于羊水正常的胎儿（P＜0.05），而羊水Ⅲ度污染的胎儿胎心监护异常率显著高于羊水Ⅰ度和Ⅱ度污染的胎儿（P＜0.01）。羊水污染新生儿窒息率显著高于无羊水污染的新生儿（P＜0.01）。羊水Ⅲ度污染的新生儿发生窒息率显著高于Ⅰ度和Ⅱ度污染的新生儿（P＜0.01）。结论 胎儿期羊水污染是胎儿宫内缺氧的早期表现，与新生儿窒息具有密切的关系。

[关键词] 新生儿窒息；羊水污染

[中图分类号] R722.12[文献标识码] B[文章编号] 1673-9701（2014）19-0147-02

Influence of foetal period meconium-stained amniotic fluid for neonatal asphyxia

YUAN Jianhua

Department of Paediatrics， Guzhen Peoples Hospital of Zhongshan City in Guangdong Province， Zhongshan 528421,China

[Abstract] Objective To discuss influence of foetal period meconium-stained amniotic fluid for neonatal asphyxia.Methods Selected 618 newborn were subjects. Abnormal fetal electrocardiogram rates andneonatal asphyxia of amniotic fluid 0 degree and Ⅰ to Ⅲ foetal period meconium-stained amniotic fluid were compared. Results Abnormal fetal electrocardiogram rates of cases with foetal period meconium-stained amniotic fluid were higher than those of cases with normal amniotic fluid（P＜0.05）， and abnormal fetal electrocardiogram rates of cases with Ⅲ degree foetal period meconium-stained amniotic fluid were higer than those of cases withⅠand Ⅱdegree foetal period meconium-stained amniotic fluid（P＜0.01）. Neonatal asphyxia rates of cases with foetal period meconium-stained amniotic fluid were higher than those of cases with normal amniotic fluid（P＜0.01）， and neonatal asphyxia rates of cases with Ⅲ degree foetal period meconium-stained amniotic fluid were higer than those of cases withⅠand Ⅱdegree foetal period meconium-stained amniotic fluid（P＜0.01）. Conclusion Fetal amniotic fluid pollution is early manifestation of fetal intrauterine hypoxia, and neonatal asphyxia has a close relationship.

[Key words] Neonatal asphyxia; Foetal period meconium-stained amniotic fluid

新生儿窒息是指由于产前、产时或产后的各种病因，使胎儿缺氧而发生宫内窘迫或娩出过程中发生呼吸、循环障碍，导致生后1分钟内无自主呼吸或未能建立规律呼吸，以低氧血症、高碳酸血症和酸中毒为主要病理生理改变的疾病[1]。严重的新生儿窒息仍然是导致新生儿死亡的主要原因之一。羊水污染是胎儿有缺氧迹象，并危及胎儿健康和生命的指标。本研究通过对618例新生儿临床资料分析，探讨羊水污染与新生儿窒息之间的关系。现报道如下。

1资料与方法

1.1一般资料

选择2013年1～6月在我院进行分娩的新生儿618例的临床资料，所有纳入的研究对象均为足月单胎。排除剖宫产、低体重儿、臀位产。其中男324例，女294例，平均胎龄（37.9±2.1）周，平均出生体重（93.3±0.7）kg。……