李媛媛

[摘要]目的 分析分析阴道镜与LEEP治疗宫颈癌前病变的临床有效性。方法 从2015年3—8月该院108例阴道镜患者中，整群选择48例经阴道镜活检病理检查诊断为宫颈癌前病变的入院者，给予阴道镜下LEEP手术治疗，分析其临床治疗效果。结果 阴道镜的活检结果和LEEP手术的病理组织诊断的总符合概率95.8%；采用LEEP刀治疗，3个月的随访的转阴率为93.75%，6个月转阴率100%。 结论 阴道镜与LEEP治疗宫颈癌前病变的临床效果显著。

[关键词] 阴道镜；LEEP；宫颈癌前病变；应用效果

[中图分类号] R713.4 [文献标识码] A [文章编号] 1674-0742（2015）11（c）-0038-02

[Abstract] Objective To analyze the effect of gynecatoptron and LEEP knife in the treatment of precancerous lesions of uterine cervix in clinic. Methods 48 cases of patients diagnosed as cervical precancerous lesions by colposcopy biopsy pathologic examination were selected from 108 cases of vaginitis patients treated in our hospital from March 2015 to August 2015 and they were given LEEP operation by colposcopy， the clinical treatment effect was analyzed. Results by the cervix biopsy， the sensitivity ，specificity， positive predictive values， negative predictive values ， misdiagnosis rate and missed diagnosis rate of HSIL were respectively 80.83%， 91.43%， 76.38%， 92.29%， 6.9% and 10.4%. and 82.45%、90.06%、77.44%、92.54%、5.3% and 10.5% of LSIL successively， the total coincidence probability of cervix biopsy results and pathological tissue diagnosis of LEEP operation was 95.8%， the rate of conversion was 93.75% after 3 months of follow-up and 100% after 6 months of follow-up by LEEP knife treatment. Conclusion The choice of gynecatoptron and LEEP operation in the treatment of patients with precancerous lesions of uterine cervix can greatly reduce trauma and avoid severe bleeding problems， the application effect of which is obvious.

[Key words] Gynecatoptron； LEEP； Precancerous lesions of uterine cervix； Application effect

该研究整群选择2015年1—8月该院收治的108例阴道镜患者，对其中48例经阴道镜活检病理检查诊断为宫颈癌前病变的入院者，给予阴道镜下LEEP手术治疗，治疗效果良好，现报道如下。

1 资料与方法

1.1 一般资料

整群选择该院收治的108例阴道镜患者中的48例阴道镜活检入院者，其年龄在21～53岁之间，平均（32.8±3.2）岁；有14例为不规则流血病患，有11例为接触性出血病患，有8例为血性白带病患，有16例无任何明显症状并经过体检发现；查体发现有33例病患有不同程度的宫颈糜烂，有15例宫颈光滑。

1.2 方法

1.2.1 术前 在阴道镜下实施活检选择VIZ-YD型的电子阴道镜来检查，在检查前2 d禁止使用阴道药物和妇科检查，并且严禁性生活，排查阴道验证，并对病患的病史与月经史进行仔细询问。在病患月经干净之后的3～10 d进行阴道镜检查。

1.2.2 术中 leep切除范围：一般宽度是是在宫颈病变周围的2～3 mm，深度则是根据阴道镜评估宫颈转化区类型而定，1型转……