稳心颗粒治疗不稳定型心绞痛伴抑郁状态60例

澹台印军1，刘华2，侯小光3，刘运莲4

(1.北京卫戍区第二干休所卫生所，北京 100036；2.北京军区政治部第三干休所卫生所，北京 100000；

3.北京卫戍区第一干休所卫生所，北京 100000；4.南华大学附属第二医院，长沙 421001)

摘要：目的分析稳心颗粒治疗不稳定型心绞痛(UAP)伴抑郁状态患者的价值。方法选取2013年5月—2014年5月本干休所诊治及住院的UAP伴抑郁状态患者60例,依据治疗方法不同分为治疗组与对照组，每组30例。治疗组患者常规治疗基础上加服稳心颗粒，对照组在常规治疗基础上加服黛力新,对比2组患者的治疗效果，治疗前、后中医证候积分、HAMD量表评分变化情况及不良反应发生情况。结果治疗组患者总有效率显著高于对照组，差异有统计学意义(P<0.05);2组患者治疗后中医证候积分和HAMD量表评分较治疗前显著下降(P<0.05)；治疗组患者治疗后中医证候积分和HAMD量表评分均显著低于对照组，差异具有统计学意义(P<0.05);2组患者不良反应发生率比较，差异无统计学意义(P>0.05)。结论稳心颗粒治疗UAP伴抑郁状态患者，可有效缓解患者抑郁状态,促进病情康复。

关键词：不稳定型心绞痛；稳心颗粒；抑郁；中医药疗法

DOI:10.13463/j.cnki.jlzyy.2015.02.011

中图分类号：R256.22文献标志码： A

文章编号：1003-5699(2015)02-0139-03

基金项目:湖南省教育厅课题(13C004)。

作者简介:澹台印军(1971-)，男，大学本科，主治医师，主要从事老年保健医学研究。

收稿日期:(责任编辑：王丹2014-11-21)

Value analysis of Wenxin granules in treating unstable angina pectoris with depression

TANTAI Yinjun1,LIU Hua2,HOU Xiaoguang3,LIU Yunlian4

(1.The Health Centre of Region II Sanitarium of Beijing Garrison,Beijing 100036,China;

2.The Health Centre of Region III Sanitarium of the Political Department of Beijing Military,Beijing 100000,China;

3.The Health Centre of Region I Sanitarium of Beijing Garrison,Beijing 100000,China;

4.The Second Hospital Affiliated to University of South China,Hengyang 421001,Hunan Province,China)

Abstract:ObjectiveTo analyze the value of Wenxin granules in treating the patients with unstable angina pectoris (UAP) accompanied by a status of depression.MethodsA total of 60 patients with UAP accompanied by a status of depression admitted in our centre from May,2013 to May,2014 were enrolled in our study and divided into the treatment group and the control group with 30 cases in each group.Based on the conventional treatment,the patients in the treatment group were additional given Wenxin granules,while the patients in the control group were administered with Deanxit.The therapeutic effect,the TCM syndrome score,the change of HAMD scale,and the occurrence of adverse reactions before and after treatment in the two groups were compared.ResultsThe total effective rate in the treatment group was significantly higher than that in the control group,the difference was statistically significant (P<0.05).The TCM syndrome score and HAMD scale after treatment in the two groups were significantly reduced when compared with those before treatment (P<0.05).The TCM syndrome score and HAMD scale after treatment in the treatment group were significantly lower than those in the control group,the difference was statistically significant (P<0.05).The comparison of the occurrence rate of adverse reactions between the two groups was not statistically different (P>0.05).ConclusionWenxin granules in treating the patients with UAP accompanied by a status of depression can effectively relieve the depression state and promote the rehabilitation.

Keywords:unstable angina pectoris;Wenxin granule;depression;Chinese medicine treatment

冠心病不稳定型心绞痛(UAP)是临床常见病，如治疗不及时可诱发急性冠脉事件,给患者生命健康造成严重的威胁[1]。有学者[2]认为，抑郁症可作为心血管事件的独立危险因素,严重降低了冠心病患者的生存率。笔者为观察稳心颗粒对UAP伴抑郁状态患者的治疗作用,选取我院收治的UAP伴抑郁状态患者，在常规治疗的基础上，分别给予稳心颗粒及黛力新治疗，观察其疗效及安全性，结果报道如下。……