禹萌++耿晓林

[摘要] 目的 分析颈动脉粥样硬化和血脂水平与脑梗塞的关系。方法 整群选取2012年8月—2013年10月于该院神经内科治疗的130例患者，74例脑梗塞患者定为观察组，56例非脑梗塞患者定为对照组，对其进行颈动脉超声检查和血脂水平检测，对两组患者的检测结果进行分析对比。结果 观察组检出率为77.03%，对照组为26.79%，观察组颈动脉粥样硬化斑块检出率明显高于对照组（P<0.05），观察组左右颈总动脉内径明显低于对照组（P<0.05），观察组甘油三酯明显高于对照组（P<0.05）。 结论 颈动脉粥样硬化与脑梗塞具有密切关系，颈动脉粥样硬化斑块形成与部分脂肪代谢异常有关，血脂水平测定和颈动脉超声检查对脑梗塞预测具有重要指导意义。

[关键词] 颈动脉粥样硬化；血脂水平；脑梗塞

[中图分类号] R7 [文献标识码] A [文章编号] 1674-0742（2015）10（a）-0009-02

Analysis of Carotid Atherosclerosis and Serum Lipid Levels with Cerebral Infarction

YU Meng1， GENG Xiao-lin2

1.Department of Neurology， People's Hospital of Zhengzhou， Zhengzhou， Henan Province， 450000 China；2.Department of Neurology， The First Affiliated Hospital of Xinxiang Medical University， Henan Province， 453100 China

[Abstract] Objective To study the relationship of carotid atherosclerosis and serum lipid levels with cerebral infarction. Methods 130 patients treated in Department of Neurology of our hospital from 2012 August to 2013 October were selected. 74 cases of them with cerebral infarction were regarded as the observation group and the other 56 cases without cerebral infarction were regarded as the control group. All of them received carotid ultrasound examination and detection of serum lipid levels. The examination results were compared and analyzed between the two groups. Results The detection rate of carotid atherosclerosis plaque was 77.03% in the observation group and 26.79% in the control group， and the former was significantly higher than the latter （P<0.05）. The left and right common carotid artery diameter was obviously shorter， while the level of triglyceride was significantly higher in the observation group than that in the control group， respectively （both P<0.05）. Conclusion Carotid atherosclerosis is closely associated with cerebral infarction. And the formation of carotid atherosclerotic plaque is related to the partial fat metabolism abnormality. Determination of blood lipid level and carotid artery ultrasonography have important guiding significance for the prediction of cerebral infarction.

[Key words] Carotid atherosclerosis； Blood lipid level； Cerebral infarction

近年来，我国脑梗死患者不断增加，其发病率呈逐年上升趋势，脑梗塞在发病之后病情通常较为凶险，且预后较差。有报道显示[1]，与代谢正常者相较代谢异常的患者的脑梗塞发生率较高，因此，临床治疗中须对患者脑梗死危险因素进行明确以开展具有针对性的防治措施和治疗手段。故该研究整群选取2012年8月—2013年10月于该院神经内科治疗的130例患者，对颈动脉粥样硬化和血脂水平与脑梗塞的关系进行了分析讨论，现报道如下。

1 资料与方法

1.1 一般资料

该研究130例患者中观察组74例（脑梗塞组），对照组56例（非脑梗塞组），其中，男性患者79例，女性患者51例，患者的年龄为49～79岁，平均年龄为（57.4±2.5）岁，130例患者全部符合第4届全国脑血管病学术会议制定的脑梗死诊断标准，均经MRI及头颅CT证实，排出由于脑动脉炎及心源性等原因所导致的脑梗塞患者。两组患者的性别、年龄及病情程度等均差异无统计学意义（P>0.05），有可比性。

1.2 方法

两组患者均进行颈动脉彩色超声多普勒检测及血脂水平测定。……