胡健

【摘 要】目的：探讨放疗联合手术治疗食管癌的临床疗效。方法：选择2010年1月～2013年6月我院收治的80例食管癌患者为研究对象，随机平均分成两组，实验组与对照组，各40例。对照组患者给予手术治疗，实验组患者实施放疗联合手术治疗，比较两组患者的临床疗效。结果：实验组患者经联合治疗后，总有效率为77.5%，较对照组总有效率32.5%有明显提高；实验组患者的局部控制率和生存率均明显优于对照组，两组比较差异有统计学意义（P<0.05）。结论：食管癌患者手术联合放疗可以显著提高患者的临床疗效，减少肿瘤的复发和转移，改善患者的生存质量，是治疗食管癌的有效方法，值得在临床推广。

【关键词】食管癌；放疗；手术；临床疗效

【文章编号】1004-7484（2014）06-3464-01

The evaluation of the clinical efficacy of radiotherapy combined with surgical

treatment of esophageal cancer

【Abstract】Objective： To evaluate the clinical efficacy of radiotherapy combined with surgical treatment of esophageal cancer. Methods： 80 cases of esophageal cancer patientsseleted for the study in our hospital from January 2010 to June 2013 were randomly divided into two groups， the experimental group and the control group， each of 40 cases. Patients in the control group were given surgery， while patients in the experimental group were treated with radiotherapy surgery. The clinical efficacy were compared between patients in the two groups. Results： The total effective rate of the experimental group patients was 77.5% which had significant increase compared with a total efficiency of 32.5% in the control group .The local control rate and survival rate of patients in the experimental group were significantly better than the control group. The difference was statistically significant （P <0.05）. Conclusion： Surgical treatment of esophageal cancer in combination with radiotherapy can significantly improve the clinical treatment efficiency， reduce tumor recurrence and metastasis and improve survival quality of life which is an effective method to treat esophageal cancer which is worthy of promotion in clinic.

【Key words】esophageal cancer； radiotherapy； surgery； clinical efficacy

食管癌是臨床常见的恶性肿瘤之一，是指由于食管腺上皮或鳞状上皮发生异常增生而形成的恶性病变[1]。目前。临床主要采用手术治疗，但术后患者的生存率不高，且晚期患者不宜采取手术治疗，因此，越来越多的患者倾向于选择放疗。有研究表明，放疗联合手术治疗食管癌的临床疗效优于单一的放疗或手术治疗，临床疗效显著[2]。本研究以2010年1月～2013年6月我院收治的80例食管癌患者为研究对象，探讨放疗联合手术治疗食管癌的临床疗效。

1 资料与方法

1.1 一般资料

选择2010年1月～2013年6月我院收治的80例食管癌患者为研究对象，所有患者均经CT检查和病理学检查确诊。将80例患者随机平均分成两组，实验组与对照组，每组各40例。实验组：男性26例，女性14例，年龄54～78岁，平均年龄65.2岁；颈段癌6例，胸上段癌8例，胸中段癌22例，胸下段癌4例；髓质型18例，缩窄型9例，溃疡型8例，蕈伞型4例，腔内型1例；ⅡB期12例，Ⅲ期22例，Ⅳ期6例。对照组：男性25例，女性15例，年龄55～80岁，平均年龄65.6岁；……