蔡金莲

【摘 要】目的 分析玉屏風散合消风散加减联合西替利嗪治疗小儿荨麻疹的临床效果。方法 选取我院2017年7月-2022年7月收治的80例荨麻疹患儿为研究对象，根据随机数字表法分为观察组与对照组，每组40例。对照组予以西替利嗪，观察组在对照组基础上加用玉屏风散合消风散加减。比较两组临床疗效、中医症状评分以及风团体征改善情况。结果 观察组治疗有效率高于对照组，差异有统计学意义（P<0.05）；两组治疗后口干口渴、心烦易怒、大便干燥、手足心热、小便短赤评分及总分均低于治疗前，且观察组低于对照组，差异有统计学意义（P<0.05）；两组治疗后风团数量、瘙痒程度、风团大小、发作频率、风团持续时间评分及总分均低于治疗前，且观察组低于对照组，差异有统计学意义（P<0.05）。结论 玉屏风散合消风散加减联合西替利嗪对小儿荨麻疹的疗效确切，可有效缓解病症，改善风团体征。

【关键词】玉屏风散合消风散；西替利嗪；小儿荨麻疹

中图分类号：R751.05 文献标识码：A 文章编号：1004-4949（2023）02-0103-04

Clinical Effect of Yupingfeng Powder and Xiaofeng Powder Combined with Cetirizine in the Treatment of Urticaria in Children

CAI Jin-lian

（Department of Ultrasound， Fozuling Street Community Health Service Center of East Lake New Technology Development Zone， Wuhan 430000， Hubei， China）

【Abstract】Objective To analyze the clinical effect of Yupingfeng powder and Xiaofeng powder combined with cetirizine in the treatment of urticaria in children. Methods A total of 80 children with urticaria admitted to our hospital from July 2017 to July 2022 were selected as the research objects. According to the random number table method， they were divided into observation group and control group， with 40 cases in each group. The control group was treated with cetirizine， and the observation group was treated with Yupingfeng powder and Xiaofeng powder on the basis of the control group. The clinical efficacy， TCM symptom score and improvement of wind group sign were compared between the two groups. Results The effective rate of treatment in the observation group was higher than that in the control group， and the difference was statistically significant （P<0.05）. After treatment， the scores of dry mouth， thirst， irritability， dry stool， hand-foot-heart heat， urine short red and total scores in the two groups were lower than those before treatment， and those in the observation group were lower than the control group， the differences were statistically significant （P<0.05）. After treatment， the number of wheals， itching degree， wheal size， seizure frequency， wheal duration score and total score of the two groups were lower than those before treatment， and the observation group was lower than the control group， the differences were statistically significant （P<0.05）. Conclusion Yupingfeng powder and Xiaofeng powder combined with cetirizine is effective in the treatment of urticaria in children， which can effectively relieve the symptoms and improve the wind group sign.

【Key words】Yupingfeng powder and Xiaofeng powder； Cetirizine； Urticaria in children

荨麻疹（urticaria）为因机体内肥大细胞活化释放出多种炎症介质，导致黏膜和皮肤血管通透性增加、小血管扩张，引起的一过性水肿反应[1，2]。目前临床以对症治疗和抗过敏治疗为主，效果迅速但短暂。此外，荨麻疹患儿停药后易复发，同时抗组胺药的嗜睡和镇静作用会严重影响荨麻疹患儿的生活、睡眠和学习情况。荨麻疹在中医学中归属于“瘾疹”范畴，《诸病源候论》中描述“邪气客于皮肤，复逢风寒相折，则起风瘙瘾疹”。……