王丽 凌云

【摘 要】目的：分析高血压、高血糖、高血脂的管控水平对老年痴呆患者的临床效果的影响。方法：将2020年6月至2021年5月间入院于我科治疗的76例老年痴呆患者选作为实对象，根据随机分配法分为两组，每组38 例。对照组采用常规治疗方法，实验组在其基础上严格控制血压、血糖及血脂水平，治疗3月后对比两组临床疗效。结果：实验组临床治疗总有疗效率、生活质量评分较对照组相比明显升高（P<0.05）。随后根据老年痴呆检查量表进行比较分析，两组治疗前无明显差异，经不同方案治疗后，实验组明显改善，差异具有统计学意义（P<0.05）。最终，实验组疾病复发率较对照组相比，也明显降低，差异具有统计学意义（P<0.05）。结论：老年痴呆患者进行三高的合理管控临床效果显著，对病情的进展具有积极的意义，提升患者的生活质量及认知水平，值得推广应用。

【关键词】高血压；高血糖；高脂血症；老年痴呆；认知功能；生活质量

Effect of hypertension， hyperglycemia and hyperlipidemia reasonable management on senile dementia

WANG Li， LING Yun

Department of geriatric psychiatry， the second people’s Hospital of Guizhou， Guiyang， Guizhou 550004， China

【Abstract】Objective： To analyze the clinical effect of the control level of hypertension， hyperglycemia and hyperlipidemia on patients with senile dementia. Methods： 76 patients with senile dementiaadmitted to our department from June 2020 to May 2021 wereselected as the real objects and randomly divided into the two groups， with 38 cases in each group. The control group was treated with routine treatment， and the experimental group strictly controlled the blood pressure， blood glucose and blood lipid levels.After 3 months ， the clinical effects of the two groups were compared. Results： The total effective rate and quality of life score of the experimental group were significantly higher than those of the control group（P<0.05）. Then， according to the Alzheimer’s examination scale， there was no significant difference between the two groups before treatment. After treatment with different schemes， the experimental group improved significantly， and the difference was statistically significant （P<0.05）. Finally， the disease recurrence rate in the experimental group was also significantly lower than that in the control group（P<0.05）. Conclusion： The reasonable control of "three highs" in patients with Alzheimer’s disease has significant clinical effect， which can effectively control the progress of the disease， improve the quality of life and cognitive level of patients， and is spread or applied.

【Key？Words】Hypertension； Hyperglycemia； Hyperlipidemia； Senile dementia； Cognitive function； Quality of life

老年痴呆是一种进行性精神衰退疾病，对患者生活質量造成直接影响[1]。当老年患者脑血管发生退行性变，继发动脉粥样硬化基础上，进一步影响脑组织血流供应，最终使大脑缺血缺氧，进而可导致老年性痴呆，如今已被许多试验所证实[2]。血糖与血脂的代谢紊乱与老年痴呆的相关性，如今已成为医学界学者备受关注的热点，诸多试验已经表明它们之间存在一定程度上的正相关的因果关系[3]。基于此，本研究分析高血压、高血糖、高血脂的合理管控对疾病的治疗效果。……