吕红

摘要：目的 探讨低分子肝素与阿司匹林用于孕晚期羊水过少的治疗效果。方法 将70例于2020年5月-2021年5月期间我院收治的孕晚期羊水过少孕妇纳入研究，并以等量电脑随机法均分成A、B两组。两组均展开常规疗法治疗，B组添加低分子量肝素钠注射液与阿司匹林治疗，并对比疗效。结果 治疗后B组羊水指数及最大羊水池深度改善情况均优于A组，顺产率高于A组，新生儿Apgar评分高于A组，对比有统计学意义（P〈0.05）。结论 低分子肝素与阿司匹林治疗孕晚期羊水过少的疗效显著，可助孕妇提升羊水量及顺产率。

关键词：低分子肝素;阿司匹林;孕晚期;羊水过少;顺产

[Abstract] Objective To investigate the therapeutic effect of low molecular weight heparin and aspirin on oligohydramnios in the third trimester of pregnancy. Methods 70 pregnant women with oligohydramnios in the third trimester treated in our hospital from May 2020 to may 2021 were included in the study，and they were divided into two groups A and B by equal amount computer random method. Both groups were treated with routine therapy，and group B was treated with low molecular weight heparin and aspirin. Results after treatment，the improvement of amniotic fluid index and maximum amniotic fluid pool depth in group B were better than those in group A，the spontaneous labor rate was higher than that in group A，and the neonatal Apgar score was lower than that in group A（P. Conclusion low molecular weight heparin and aspirin are effective in the treatment of oligohydramnios in the third trimester of pregnancy，which can help pregnant women increase the amount of amniotic fluid and the rate of spontaneous delivery.

[Key words] low molecular weight heparin;aspirin;Third trimester;Oligohydramnios;Spontaneous labor

孕晚期羊水过少通常为孕妇喝水少、出汗多等生活习惯导致，同时也与胎盘功能不足、胎儿慢性缺氧相关【1】。需要进一步做胎心监护等客观检查来评估，如果胎心监护明显异常则要考虑及时终止妊娠以抢救胎儿【2】。而部分研究指出将低分子肝素与阿司匹林应用到孕晚期羊水过少的治疗中，可快速改善与提升羊水指数，并提升顺产率【3】。而我院为了提升孕晚期羊水过少的治疗效果，特将低分子肝素与阿司匹林的应用效果展开研究，以期惠及广大孕孕妇。现做如下报告：

1 资料和方法

1.1一般资料

经院内伦理委员会批准，将70例于2020年5月-2021年5月期间我院收治的孕晚期羊水过少孕妇纳入研究，并以等量电脑随机法均分成A、B两组。A组年龄23-34岁，均值（26.26±2.58）岁;孕周32-36周，均值（33.52±1.33）周.B组年龄24-34岁，均值（26.41±2.60）岁;孕周32-36周，均值（33.67±1.35）周。对比孕妇一般资料差异无统计学意义（P>0.05）。……