陈丽雅

[摘要]目的分析經颅磁刺激治疗伴有焦虑的失眠症患者的临床效果。方法选取2019年2月至2021年2月茂名市第三人民医院收治的76例伴有焦虑的失眠症患者作为研究对象，根据治疗方法不同分为对照组和试验组，每组各38例。对照组采用盐酸文拉法辛缓释胶囊治疗，试验组采用经颅磁刺激联合盐酸文拉法辛缓释胶囊治疗。比较两组治疗前后焦虑自评表（SAS）、匹兹堡睡眠质量指数量表（PSQI）、多导睡眠图参数（PSG）。结果治疗后，试验组 SAS 评分低于对照组，差异有统计学意义（ P <0.05）。试验组 PSQI 评分低于对照组，差异有统计学意义（ P <0.05）。试验组 SOL、WASO、As 参数低于对照组，差异有统计学意义（ P <0.05）。试验组 TST、SE 参数高于对照组，差异有统计学意义（ P <0.05）。结论经颅磁刺激治疗可有效帮助患者调节焦虑情绪，改善睡眠问题，减少患者助眠药的使用剂量与频率，提高患者的生活质量，促进患者的康复，值得应用与推广。

[关键词]中药抗栓胶囊;针药结合治疗;焦虑失眠症;康复治疗;匹兹堡睡眠质量

[中图分类号] R749.7+2;R74  [文献标识码] A   [文章编号]2095-0616（2021）23-0199-03

Clinical observation of transcranial magnetic stimulation in the treatment of insomniacs with anxiety

CHEN  Liya

Rehabilitation Center， the Third People's Hospital of Maoming City， Guangdong， Maoming 525200， China

[Abstract] Objective To analyze the clinical effect of transcranial magnetic stimulation （TMS） in the treatment of insomniacs with anxiety. Methods A total of 76 insomniacs with anxiety admitted to the Third People's Hospital of Maoming City from February 2019 to February 2021 were selected as study subjects and divided into the control group and the experimental group according to different treatment methods， with 38 cases in each group. The control group was treated with venlafaxine hydrochloride sustained-release capsules， while the experimental group was treated with TMS combined with venlafaxine hydrochloride sustained-release capsules. The self rating anxiety scale （SAS）， Pittsburgh Sleep Quality Index scale （PSQI）， and polysomnographic parameters （PSG） were compared between the two groups after treatment. Results After treatment， the SAS scores of the experimental group were lower than those of the control group， with statistically significant difference （P <0.05）. The PSQI scores of the experimental group were lower than those of the control group， with statistically significant difference （P <0.05）. The values of SOL， WASO and As parameters in the experimental group were lower than those in the control group， with statistically significant differences （P <0.05）. The total sleep time （TST） and the value of SE parameter in the experimental group were higher than those in the control group， with statistically significant differences （P <0.05）. Conclusion TMS is effective in helping patients regulate anxiety， and improving their sleep problems. In addition， it can reduce the dose and frequency of sleeping aids for patients， improve their quality of life， and promote rapid rehabilitation. Therefore， it is worthy of application and promotion.

[Key words] Antithrombotic capsule; Combined treatment of acupuncture and medicine; Insomnia with anxiety; Rehabilitation therapy; Pittsburgh sleep quality index

近年来，受工作与生活压力增加的影响，焦虑症的发病人数呈持续递增的趋势，失眠是焦虑症的常见临床表现，患者普遍存在入睡困难、睡眠质量低的症状[1-2]。有关研究表明，失眠焦虑症多与遗传、自我调节、环境等因素有关，常规药物治疗的方式虽可帮助患者入睡，但会导致患者出现药物依赖性，还会引发较多的不良反应，因此亟需采取合理有效的治疗措施帮助患者抑制病情的发展，改善临床症状[3-5]。基于此，本研究选取2019年2月至2021年2月76例伴有焦虑的失眠症患者分别予以不同治疗措施，以期研究最佳的治疗方式，现报道如下。

1资料与方法

1.1一般资料

选取2019年2月至2021年2月茂名市第三人民医院76例伴有焦虑的失眠症患者为研究对象，按照治疗方法不同分为对照组和试验组，每组各38例，对照组行盐酸文拉法辛缓释胶囊治疗，试验组行经颅磁刺激联合盐酸文拉法辛缓释胶囊治疗。……