李洪梅

摘要：目的 分析左氧氟沙星三联疗法与阿莫西林三联疗法治疗消化溃疡疾病的临床效果。方法 选取70例消化性溃疡患者为研究对象，以随机抽签法分组，各35例，对照组实施阿莫西林三联疗法治疗，观察组采用左氧氟沙星三联疗法治疗。对比治疗效果。结果 观察组用药有效率无统计学差异（P>0.05）;观察组用药不良反应发生率与对照组相比无统计学差异（P>0.05）。结论 左氧氟沙星三联疗法与阿莫西林三联疗法治疗消化性溃疡的效果相当，且用药安全性均较高，临床推广应用价值高。

关键词：消化性溃疡;三联疗法;左氧氟沙星;阿莫西林

[Abstract]Objective To analyze the clinical effect of levofloxacin triple therapy and amoxicillin triple therapy in the treatment of peptic ulcer disease. Methods 70 patients with peptic ulcer were randomly divided into two groups，35 cases in each group. The control group was treated with amoxicillin triple therapy，and the observation group was treated with levofloxacin triple therapy. The therapeutic effect was compared. Results there was no significant difference in the effective rate of the observation group（P > 0.05）;There was no significant difference in the incidence of adverse reactions between the observation group and the control group（P > 0.05）. Conclusion the effect of levofloxacin triple therapy and amoxicillin triple therapy in the treatment of peptic ulcer is equivalent，and the drug safety is high，and the clinical application value is high.

[Key words]peptic ulcer;Triple therapy;Levofloxacin;Amoxicillin

消化性潰疡是消化内科常见病，一般以十二指肠溃疡、胃溃疡为常见，对患者的正常工作及生活影响较大【1】。而幽门螺杆菌感染是消化性溃疡发病的重要原因，也是导致疾病反复发作的原因之一【2】。而彻底清除幽门螺杆菌，可降低溃疡面受到的刺激，为溃疡修复提供充足的时间【3】。目前，治疗幽门螺杆菌导致的消化性溃疡以三联疗法最为常见，而阿莫西林及左氧氟沙星两种不同三联疗法的治疗效果各具差异【4】。本次研究开展左氧氟沙星三联疗法与阿莫西林三联疗法治疗消化性溃疡的对比分析，目的是提供高效的临床治疗方案。现报道如下。

1 资料与方法

1.1 一般资料

将2019年11月-2020年10月收治的70例消化性溃疡患者纳入研究，以随机抽签法分组，各35例。观察组，男20例，女15例，年龄18-68岁，平均（46.2±8.1）岁。对照组，男23例，女12例，年龄22-70岁，平均（46.8±7.5）岁。……