张长春

【摘要】 目的：探讨氟哌啶醇联合认知行为疗法对精神分裂症患者自知力及PANSS评分的影响。方法：选取2019年8月-2020年2月于本院进行治疗的100例精神分裂症患者，依据干预方案不同分为对照组和研究组，各50例。对照组给予氟哌啶醇治疗，研究组给予氟哌啶醇联合认知行为疗法治疗。对比两组患者自知力评分、PANSS评分及临床疗效。结果：干预后，观察组自我反思因子评分及综合指数评分均高于对照组，自我确定因子评分低于对照组，差异均有统计学意义（P<0.05）。干预后，两组阳性症状评分、阴性症状评分及一般病理症状评分均降低，研究组比对照组均更低，差异均有统计学意义（P<0.05）。研究组总有效率高于对照组，差异有统计学意义（P<0.05）。结论：在精神分裂症患者的临床治疗中，应用氟哌啶醇联合认知行为疗法干预，可显著提升临床疗效，改善患者自知力水平，还能降低PANSS评分，应用效果理想，值得推广。

【关键词】 氟哌啶醇 认知行为疗法 精神分裂症患者 自知力 PANSS评分

[Abstract] Objective： To explore the effect of Haloperidol combined with cognitive behavioral therapy on insight and PANSS score of schizophrenics. Method： A total of 100 patients with schizophrenia who were admitted to our hospital for treatment from August 2019 to February 2020 were selected， they were divided into control group and research group according to different treatment regimens， 50 cases in each group. The control group was treated with Haloperidol， the research group was treated with Haloperidol combined with cognitive behavioral therapy. The insight score， PANSS score and clinical effect of the two groups were compared. Result： After intervention， the scores of self-reflection factor and comprehensive index in the observation group were higher than those in the control group， while the scores of self-confirmation factor in the observation group was lower than that in the control group， the difference was statistically significant （P<0.05）. After intervention， positive symptom score， negative symptom score and general pathological symptom score were decreased in both groups， in the research group lower than those in the control group， the differences were statistical significance （P<0.05）. The total effective rate of the research group was higher than that of the control group， the difference was statistically significant （P<0.05）. Conclusion： In the clinical treatment of schizophrenics， Haloperidol combined with cognitive behavioral therapy can significantly improve the clinical efficacy， improve the level of patients self-knowledge， reduce the PANSS score， the application effect is ideal， it can be considered to be popularized.

[Key words] Haloperidol Cognitive behavioral therapy Schizophrenia Insight PANSS score

First-authors address： Mental Health Hospital of Fangshan District， Beijing 102405， China

doi：10.3969/j.issn.1674-4985.2021.08.038

精神分裂癥属于重性精神类疾病，且其病因尚不能明确，该病起病缓慢，患者多有认知功能损害等核心症状，同时表现出思维、行为跟环境不协调，且复发率较高，给患者的社会回归及康复带来严重影响[1]。当前临床多应用药物治疗，但由于患者心理状态、外界生物及社会等多方因素均会影响临床疗效及预后，患者认知功能降低、社会功能衰退，长期用药治疗也会出现不良反应，不利于病情恢复[2-3]。由于精神分裂症患者多不会出现智能和意识障碍，所以在临床药物治疗为主的同时，做好健康教育，更利于患者自我认知及生活质量的提升[4]。为此本研究对患者应用氟哌啶醇联合认知行为疗法干预，同时将该治疗方案对患者自知力及PANSS评分的影响进行以下探究，现报道如下。

1 资料与方法

1.1 一般资料 选取2019年8月-2020年2月于本院进行治疗的100例精神分裂症患者。……