心力衰竭合并室性心律失常的系统概述
2021-05-10闫奎坡朱翠玲朱明军孙彦琴刘新灿
闫奎坡 朱翠玲 朱明军 孙彦琴 刘新灿
【摘要】 室性心律失常是引起血流动力学紊乱、心脏性猝死等恶性事件的主要原因,已成为医学界公认的事实,其复杂的发病机制、快速的病情进展、较高的致死率至今困扰临床医师,给患者的生命财产、社会经济带来巨大损害。近年来,植入型心脏复律除颤器、射频消融术的临床应用已为许多患者带去福音,然而,受操作技术水平、经济条件等诸多因素的限制,这些治疗手段在许多基层医院都无法展开实施。因此,系统认识心力衰竭合并室性心律失常的流行病学特点、发病机制、评估手段、诊疗策略等有利于减少恶性事件的发生,挽救患者生命。
【关键词】 心力衰竭 室性心律失常
[Abstract] It is an accepted fact in the medical profession that ventricular arrhythmias can lead to many adverse events such as hemodynamic disorders, sudden cardiac death and so on. Its complex mechanisms, rapid disease progression and high fatality rate have plagued clinicians until now and bring great damage to patients life and property as well as social economy. In recent years, the application of implantable cardiovertor defibrillator, radiofrequency ablation have brought gospel to many patients, however, many local hospitals cannot implement it due to the limits of skill, economic conditions and so forth. So the systemic understanding the epidemiology, mechanisms, ways of evaluation, treatment strategies of heart failure with ventricular arrhythmias can help reduce the occurrence of adverse events.
[Key words] Heart failure Ventricular arrhythmias
First-authors address: The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou 450000, China
doi:10.3969/j.issn.1674-4985.2021.08.046
泵衰竭或心臟性猝死(sudden cardiac death,SCD)是引起心力衰竭(heart failure,HF)患者死亡的主要原因,而50%~75% SCD的发生与室性快速性心律失常密切有关[1]。室性早搏(包括频发室早、室速)可加快恶化心衰患者的病情,引起急性血流动力学障碍,进一步出现的室性扑动(室扑)和心室颤动(室颤)、心脏性猝死等恶性事件是引起心力衰竭患者死亡的主要原因,已成为医学界公认的事实,较高的病死率至今困扰临床医师,给心衰的治疗带来了巨大挑战[2]。本文将通过对近年来发表的文献进行研究,分别从心衰合并室早的流行病学、发病机制、室性心律失常的临床分类和筛查、药物及器械治疗等方面进行论述,以期更好地提高临床医师及科研人员对疾病的认识,进行规范化治疗,降低心力衰竭患者的死亡率。……
