王珍 黄莉

【摘 要】目的：探讨放置宫内节育器与继发性不孕之间的关联性。方法：以自愿原则从2020年1月至2020年12月于我院接受孕前检查的健康受检者中依据筛选条件选取2000例入组研究，其中1000例为首次分娩后放置节育器者，其余1000例为首次分娩后采取其他避孕措施者，分别记为对照组和研究组，就两组受检者继发性不孕发生率进行评价和分析，同时就节育器和继发性不孕之间的关联性展开探讨。结果：研究组受检者继发性不孕发生率略高于对照组，差异不具有统计学意义（P>0.05）；经logistic回归分析，宫内节育器和继发性不孕发生之间无显著关联性（P>0.05）。结论：放置功能节育器并不会增加继发性不孕发生风险，是一种较为可靠的避孕技术。

【关键词】宫内节育器；继发性不孕；队列研究

A cohort study on the relationship between IUD placement and secondary infertility

Wang Zhen1， Huang Li2

1.The Peoples Government of Xigang Town， Tengzhou City， Tengzhou Shandong 277519， China；

2.Xigang Central Health Center， Tengzhou City， Tengzhou Shandong 277519， China

【Abstract】Objective： To explore the relationship between the placement of the intrauterine device and secondary infertility.Methods：On a voluntary basis，2000 cases were selected from the healthy subjects who received pre-pregnancy check-ups in our hospital from January 2020 to December 2020. According to the screening conditions，2000 cases were enrolled in the study， of which 1000 cases were placed after the first childbirth，and the rest 1000 cases were those who took other contraceptive measures after the first childbirth. They were recorded as the control group and the study group， respectively. The incidence of secondary infertility in the two groups was evaluated and analyzed. At the same time， the IUD and secondary infertility were evaluated and analyzed. Exploring the relevance between them. Results： The incidence of secondary infertility in the study group was slightly higher than that of the study group， and the difference was not statistically significant（P>0.05）； After logistic regression analysis showed that there was no significant correlation between the incidence of IUD and secondary infertility（P>0.05）.Conclusion： The placement of a functional IUD will not increase the risk of secondary infertility， and it is a relatively reliable contraceptive technique.

【Key？Words】Intrauterine device； Secondary infertility； Cohort study

宮内节育器是临床中较为常用的女性避孕技术，我国约2.1亿妇女使用过宫内节育器，1.1亿妇女仍在继续使用宫内节育器。根据临床调查研究，宫内节育器是一种可靠的避孕技术，避孕有效率在95%以上，有些使用宫内节育器妇女产生了“二胎”意愿并选择摘除宫内节育器，但摘除后有妇女发生了继发性不孕，并将责任归咎于使用宫内节育器[1-2]。为明确放置宫内节育器和继发性不孕之间的关联性，遂展开本组研究，报道如下。

1 资料与方法

1.1 一般资料

从2020年1月至2020年12月于我院进行孕前检查的受检者根据筛选条件选取2000例入组研究，其中1000例为放置宫内节育器者，1000例为使用其他技术避孕者，年龄24岁～35岁，平均年龄（30.35±4.39）岁，均为健康育龄女性。