APP下载

奥美拉唑联用半夏泻心汤对慢性萎缩性胃炎的疗效探讨

2021-02-03杜军军

婚育与健康 2021年22期

杜军军

【摘 要】目的:探讨奥美拉唑联用半夏泻心汤对慢性萎缩性胃炎的疗效。方法:选取我院100例慢性萎缩性胃炎患者,随机分成两组。对照组仅口服奥美拉唑治疗,观察组采取奥美拉唑联用半夏泻心汤治疗。结果:观察组的治疗有效率明显高于对照组(P<0.05);治疗后,两组的肠化评分和胃黏膜病理萎缩评分均明显降低(P<0.05),且观察组更低(P<0.05);治疗后,两组的胃满烦闷、上腹疼痛、反酸反胃和食欲不振评分均明显降低(P<0.05),且观察组更低(P<0.05)。结论:奥美拉唑联用半夏泻心汤对慢性萎缩性胃炎有较为显著的疗效,值得进行推广。

【关键词】奥美拉唑;半夏泻心汤;慢性萎缩性胃炎

Study on the curative effect of omeprazole combined with Banxia Xiexin Decoction on chronic atrophic gastritis

Du Junjun Yuyang District Hospital of Traditional Chinese Medicine, Yulin City, Shaanxi Province, Yulin, Shaanxi, 719000, China

【Abstract】Objective:To investigate the effect of omeprazole combined with Banxia Xiexin Decoction on chronic atrophic gastritis. Methods:A total of 100 patients with chronic atrophic gastritis admitted to our hospital were selected and randomly divided into two groups. The control group was treated with only oral omeprazole, and the observation group was treated with omeprazole combined with Banxia Xiexin Decoction. Results:The effective rate of treatment in the observation group was significantly higher than that in the control group (P<0.05); after treatment, the scores of intestinal metaplasia and gastric mucosal atrophy in the two groups were significantly reduced (P<0.05), and the observation group was even lower (P<0.05) After treatment, the scores of stomach fullness, epigastric pain, acid reflux and loss of appetite in the two groups were significantly reduced (P<0.05), and the observation group was even lower (P<0.05). Conclusion:Omeprazole combined with Banxia Xiexin Decoction has a significant effect on chronic atrophic gastritis and is worthy of promotion.

【Key?Words】Omeprazole; Banxia Xiexin Decoction; Chronic atrophic gastritis

慢性萎縮性胃炎指的是以胃黏膜变薄,广泛或者部分的胃黏膜固有腺体萎缩,黏膜肌层增厚等多种病理改变为主的一种慢性炎症疾病,而且常常伴有肠上皮化生、不典型增生和炎性反应,被列为属于胃癌前状态[1]。临床治疗的目的是改善胃黏膜炎性反应以及减轻症状,治疗上需要遵循个体化原则,尽可能针对病因进行治疗[2]。本研究主要分析了奥美拉唑联用半夏泻心汤对慢性萎缩性胃炎的疗效。

1 资料与方法

1.1 一般资料

选取2018年1月至2020年12月我院收治的100例慢性萎缩性胃炎患者,随机分为两组。观察组50例,男23例,女27例,年龄35岁~72岁,平均年龄(52.13±4.96)岁,病程2年~14年,平均病程(8.73±1.49)年,体重41kg~115kg,平均体重(57.43±9.84) kg,Hp阳性22例。对照组50例,男24例,女26例,年龄34岁~72岁,平均年龄(53.07±5.24)岁,病程2年~14年,平均病程(8.69±1.38)年,体重41kg~115kg,平均病程(57.29±8.65) kg,Hp阳性23例。两组的基线资料具有可比性(P>0.05)。

1.2 方法

对照组仅服用奥美拉唑肠溶胶囊治疗,每天1次,每次1粒。

观察组采取奥美拉唑联用半夏泻心汤治疗,半夏泻心汤的组成为:黄芩8 g、半夏12 g、干姜6 g、人参8 g、炙甘草6g、大枣4枚、黄连5 g,每天1剂。均治疗3个月。

1.3 观察指标

(1)治疗有效率分为痊愈、显效、有效和无效,有效率为前三者总例数占比;(……

登录APP查看全文