李冬梅

【摘要】 目的：探討低剂量米索前列醇置阴道后穹隆与低位水囊促宫颈成熟后催产素引产的效果。方法：选择2017年3月-2019年3月笔者所在医院90例孕晚期促宫颈成熟引产产妇，随机分为两组，各45例。对照组行低位水囊引产，观察组行低剂量米索前列醇置阴道后穹隆引产，比较两组促宫颈成熟效果、分娩指标及新生儿Apgar评分。结果：观察组促宫颈成熟总有效率为97.78%，高于对照组的86.67%，差异有统计学意义（P<0.05）;观察组引产至临产时间、总产程时间均短于对照组，差异均有统计学意义（P<0.05）;两组产后出血量、新生儿Apgar评分比较，差异均无统计学意义（P>0.05）。结论：与低位水囊相比，孕晚期促宫颈成熟引产产妇采用低剂量米索前列醇置阴道后穹隆可进一步提升宫颈成熟效果，缩短引产时间及产程时间，且不会对母婴健康产生影响，应用价值较高。

【关键词】 引产 米索前列醇 低位水囊 催产素

doi：10.14033/j.cnki.cfmr.2020.13.060 文献标识码 B 文章编号 1674-6805（2020）13-0-02

Effects of Low Dose Misoprostol into the Posterior Fornix of Vagina and Low Water Bladder for Cervical Maturation on Induced Labor by Oxytocin/LI Dongmei. //Chinese and Foreign Medical Research， 2020， 18（13）： -146

[Abstract] Objective： To investigate the effects of low dose Misoprostol into the posterior fornix of vagina and low water bladder for cervical maturation on induced labor by Oxytocin. Method： A total of 90 parturients who promoted cervical maturation and induced labor in the third trimester of pregnancy in our hospital from March 2017 to March 2019 were selected and randomly divided into two groups， 45 cases in each group. The control group was induced by low water bladder， and the observation group was induced by Misoprostol into the posterior fornix of vagina to induce. The effects of cervical maturation， delivery indexes and neonatal Apgar score were compared between the two groups. Result： The total effective rate of cervical maturation in the observation group was 97.78%， which was significantly higher than 86.67% of the control group， and the difference was statistically significant （P<0.05）. The time from induced labor to parturition and total duration of labor were shorter than those of the control group， and the differences were statistically significant （P<0.05）. And the amount of postpartum hemorrhage and neonatal Apgar score were compared between the two groups， and the differences were not statistically significant （P>0.05）. Conclusion： Compared with the low water bladder， low dose Misoprostol into the posterior fornix of vagina in parturients who promoted cervical maturation and induced labor in the third trimester of pregnancy can further improve the effect of cervical maturation， shorten the time of induced labor and the duration of labor， and will not affect the health of mother and child， and has a higher value.

[Key words] Induced labor Misoprostol Low water bladder Oxytocin

First-authors address： Songzi Traditional Chinese Medicine Hospital， Songzi 434200， China

足月产妇易受到各种因素影响而出现分娩问题，对产妇及新生儿造成较大危害[1]。为保证母婴健康，针对孕晚期伴危险因素的产妇需进行诱导分娩，但对于宫颈不成熟产妇需先采取促宫颈成熟措施。虽然可采用催产素促宫颈成熟，但效果有限，需配合其他治疗方案。米索前列醇可起到软化宫颈的作用，而低位水囊可通过扩张宫颈以促宫颈成熟[2]。本次研究对孕晚期促宫颈成熟引产产妇采用低剂量米索前列醇置阴道后穹隆、低位水囊的效果进行探讨，具体如下。

1 资料与方法

1.1 一般资料

选择2017年3月-2019年3月笔者所在医院90例孕晚期促宫颈成熟引产产妇。纳入标准：（1）具有引产指征;（2）完整胎膜，头先露;（3）胎心监护正常;（4）宫颈Bishop评分<6分[3]。排除标准：头盆不称、胎膜早破及其他引产禁忌证。随机分为两组，各45例。对照组年龄20～38岁，平均（29.42±2.03）岁;孕周37～41周，平均（39.48±0.45）周。观察组年龄20～38岁，平均（29.18±2.05）岁;孕周37～41周，平均（39.52±0.46）周。两组一般资料比较，差异均无统计学意义（P>0.05）。……