张飞捷 杨龙峰 陈勇 廖振辉 巫雄辉 邱海兵

【摘要】 目的：探討无创呼吸机应用于慢性阻塞性肺疾病（COPD）合并Ⅱ型呼吸衰竭患者中的临床效果。方法：对2017年3月-2019年5月本医院收治的70例慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者展开研究，通过随机双盲法将患者分为试验组和对照组，每组35例。试验组采用常规临床治疗加无创呼吸机辅助通气治疗方案，对照组采用常规临床治疗方案，记录两组患者的临床指标。结果：试验组治疗有效率、临床治疗满意度比对照组高，差异有统计学意义（P<0.05）;试验组治疗后的心率、呼吸频率、动脉血二氧化碳分压比对照组低，差异有统计学意义（P<0.05）;试验组治疗后动脉血氧分压比对照组高，差异有统计学意义（P<0.05）。结论：无创呼吸机辅助通气治疗慢阻肺合并Ⅱ型呼吸衰竭患者效果明显，临床治疗满意度高，值得在临床上推广。

【关键词】 无创呼吸机 慢阻肺 Ⅱ型呼吸衰竭 心率

doi：10.14033/j.cnki.cfmr.2020.13.056 文献标识码 B 文章编号 1674-6805（2020）13-0-03

Application of Non-invasive Ventilator in COPD Patients with Type Ⅱ Respiratory Failure/ZHANG Feijie， YANG Longfeng， CHEN Yong， LIAO Zhenhui， WU Xionghui， QIU Haibing. //Chinese and Foreign Medical Research， 2020， 18（13）： -138

[Abstract] Objective： To explore the clinical effect of non-invasive ventilator in chronic obstructive pulmonary disease （COPD） patients with type Ⅱ respiratory failure. Method： A total of 70 patients with chronic obstructive pulmonary disease and type Ⅱ respiratory failure admitted to our hospital from March 2017 to May 2019 were enrolled. The patients were divided into experimental group and control group by random double-blind method， 35 patients in each group. The experimental group was treated with conventional clinical treatment plus non-invasive ventilator assisted ventilation， the control group was treated with routine clinical treatment. The clinical indicators of the two groups of patients were recorded. Result： The total effective rate and the total clinical treatment satisfaction rate of the experimental group were higher than those of the control group， and the differences were statistically significant （P<0.05）. The heart rate， respiratory rate and arterial blood carbon dioxide partial pressure after treatment in the experimental group were lower than those in the control group， and the differences were statistically significant （P<0.05）. The arterial oxygen partial pressure after treatment in the experimental group was higher than that in the control group， and the difference was statistically significant （P<0.05）. Conclusion： Non-invasive ventilator assisted ventilation in patients with chronic obstructive pulmonary disease and type Ⅱ respiratory failure is effective， and the clinical treatment satisfaction is high， which is worthy of clinical promotion.

[Key words] Non-invasive ventilator Chronic obstructive pulmonary disease Type Ⅱ respiratory failure Heart rate

First-authors address： Heyuan Peoples Hospital， Heyuan 517000， China

慢性阻塞性肺疾病患者由于气流受到一定限制引发机体换气功能出现异常，导致肺部通气出现异常，容易引发呼吸衰竭，故慢性阻塞性肺疾病合并呼吸衰竭在临床治疗中非常多见，存在比较大的患病率，针对慢性阻塞性肺疾病合并呼吸衰竭患者应开展尽早临床治疗，进而促使其病情好转，促进其预后情况获得改善[1]。本文将2017年3月-2019年5月本医院收治的70例慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者归入指标研究资料，研究无创呼吸机辅助通气治疗方案用于慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者的临床治疗效果及其应用价值，现报道如下。

1 资料与方法

1.1 一般资料

对2017年3月-2019年5月本医院收治的70例慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者展开研究，纳入标准：患者经临床诊断同时存在慢性阻塞性肺疾病及Ⅱ型呼吸衰竭。……