曾丽萍

【摘要】 目的：研究在妊娠晚期对孕妇B族链球菌进行快速抗原检测结果，以及对妊娠结局的影响。方法：抽取笔者所在医院2018年2月-2019年3月收治的400例进行常规检验和分娩的产妇进行研究，均在妊娠周期超过35周时检测B族链球菌，并对B族链球菌感染情况进行筛查。后将400例产妇根据检测结果分为阴性、阳性组，对比两组妊娠结局、新生儿结局情况。结果：（1）400例产妇B族链球菌快速抗原检测结果表明，阴性380例，占比95.00%;阳性20例，占比5.00%。（2）380例阴性产妇，妊娠不良结局发生率2.60%，20例阳性产妇，妊娠不良结局发生率75.00%，差异有统计学意义（P<0.05）。（3）380例阴性产妇，新生儿不良结局发生率2.10%，20例阳性产妇，新生儿不良结局发生率50.0%，差异有统计学意义（P<0.05）。结论：B族链球菌感染参与了妊娠过程，会导致产妇和新生儿出现不良结局，因此在妊娠晚期对产妇进行B族链球菌快速抗原检测至关重要。

【关键词】 妊娠晚期 B族链球菌 快速抗原检测 妊娠结局 新生儿结局

doi：10.14033/j.cnki.cfmr.2020.18.064 文献标识码 B 文章编号 1674-6805（2020）18-0-03

Impact of Pregnant Womens Group B Streptococcus Testing in Late Pregnancy on Pregnancy Outcomes/ZENG Liping. //Chinese and Foreign Medical Research， 2020， 18（18）： -152

[Abstract] Objective： To study the results of rapid antigen detection of pregnant womens group B streptococcus in late pregnancy and the effect on pregnancy outcome. Method： A total of 400 pregnant women who were admitted to our hospital from February 2018 to March 2019 for routine examination and delivery were studied. All of them were tested for group B streptococcus when their gestation cycle exceeded 35 weeks. Screen for infection. After that， 400 cases of pregnant women were divided into negative and positive groups according to the test results， and the pregnancy outcome and neonatal outcome were compared between the two groups. Result： （1） In 400 cases of pregnant women underging rapid antigen testing for group B streptococci， 380 cases were negative， accounting for 95.00%， 20 cases were positive， accounting for 5.00%. （2） The incidence of adverse pregnancy outcomes was 2.60% in 380 negative mothers and 75.00% in 20 positive mothers （P<0.05）. （3） The incidence of adverse neonatal outcomes in 380 negative mothers was 2.10%， and the incidence of adverse neonatal outcomes in 20 positive mothers was 50.0%， the difference was statistically significant （P<0.05）. Conclusion： Group B streptococcal infection is involved in the pregnancy process， which can lead to adverse outcomes for women and newborns. Therefore， it is important to perform rapid B antigen testing for women in the third trimester.

[Key words] Late pregnancy Group B streptococcus Rapid antigen detection Pregnancy outcome Neonatal outcome

First-authors address： Heping County Peoples Hospital， Heping 517200， China

B族溶血性链球菌属于革兰氏阳性链球菌，同时该菌种也是女性阴道、直肠组织内最常见的菌种[1]。一般来说，阴道内的微生物菌群和宿主体内的周围环境间是一种平衡状态，但若女性已经怀孕，体内雌激素水平会出现明显的升高，相应的阴道内糖原、乳酸杆菌等优势菌会大量滋生从而导致机体内原本平衡的微生物群出现紊乱[2];其中以妊娠晚期最为明显，受阴道黏膜水肿等因素的影响，极易诱发生殖道B族溶血性链球菌感染，从而导致不良妊娠结局，對新生儿生命安全产生严重威胁[3]。可见，在妊娠晚期实施B族链球菌快速抗原检测至关重要。为进一步研究在妊娠晚期对B族链球菌进行快速抗原检测的结果，以及对妊娠结局的影响，此研究特选取笔者所在医院近一年内的400例妊娠晚期产妇展开研究，现汇报如下。……