王影

[摘要] 目的 討论妊娠期糖尿病（GDM）采用胰岛素泵皮下注射和多次胰岛素皮下注射的临床效果。 方法 选取2017年1月～2019年8月我院收纳GDM患者92例，按随机数字表法将其中46例纳进对照组（按多次胰岛素注射），余46例纳进实验组（按胰岛素泵注射），比较两组治疗效果。 结果 两组治疗前FPG、2 hPBG血糖指标比较无差异（P>0.05），治疗后实验组血糖指标明显低于对照组（P<0.05）;实验组治疗总有效率为97.83%，对照组为78.26%，实验组总有效率明显高于对照组（P<0.05）;两组早产、妊娠高血压、剖宫产比较无统计学意义（P>0.05），但实验组新生儿低血糖、巨大儿、胎儿窘迫明显低于对照组（P<0.05）。 结论 GDM患者采用胰岛素泵皮下注射效果显著，有效提高治疗效果，且降低不良症状发生，有效控制血糖指标，因此值得临床应用及推广。

[关键词] 胰岛素泵注射;胰岛素笔注射;妊娠期糖尿病;临床效果

[中图分类号] R714.256          [文献标识码] B          [文章编号] 1673-9701（2020）18-0071-03

Comparison of the efficacy of insulin pump subcutaneous injection and multiple insulin subcutaneous injections in the treatment of gestational diabetes mellitus

WANG Ying

Department of Obstetrics， Central Hospital Affiliated to Shenyang Medical College， Shenyang   110000， China

[Abstract] Objective To discuss the clinical effect of insulin pump subcutaneous injection and multiple insulin subcutaneous injections in gestational diabetes mellitus（GDM）. Methods From January 2017 to August 2019， 92 patients with GDM were admitted to our hospital. According to the random number table method， 46 of them were included in the control group（given multiple insulin injections）， and the remaining 46 were included in the experimental group（injected by insulin pump）. The treatment value was compared between the two groups. Results There was no difference in blood glucose indices of FPG and 2 hPBG before treatment between the two groups（P>0.05）. After treatment， the blood glucose index in the experimental group was significantly lower than that in the control group（P<0.05）; the total effective rate in the experimental group was 97.83%， and the control group was 78.26%. The total effective rate in the experimental group was significantly higher than that in the control group（P<0.05）; there was no statistically significant difference in premature delivery， pregnancy-induced hypertension and cesarean section between the two groups（P>0.05）. However， the hypoglycemia， macrosomia and fetal distress in the experimental group were significantly lower than those in the control group（P<0.05）. Conclusion The subcutaneous injection of insulin pump in patients with GDM has a significant effect， which effectively improves the treatment effect， reduces the occurrence of adverse symptoms， and effectively controls blood glucose indices， so it is worthy of clinical application and promotion.

[Key words] Insulin pump injection; Insulin pen injection; Gestational diabetes mellitus（GDM）; Clinical effect

妊娠期糖尿病（gestational diabetes mellitus，GDM）是女性妊娠期常见并发症之一，该疾病主要是怀孕后体内各种激素分泌水平增加，且妊娠机体出现一系列慢性应激反应，导致胎盘分泌各种对抗胰岛素的激素，且分泌量会随着孕周增加而增多，因此患者可出现高胰岛素血症、高脂血症以及高血糖。据有关研究显示，高糖可使胚胎发育异常甚至死亡，且流产率可达到15%～30%，严重影响胎儿生命健康[1]。目前以传统多次胰岛素皮下注射为主要手段，由于该方式注射剂量不够准确，从而导致低血糖发生率较高[2]。因此临床为GDM患者研究有效的治疗方案具有重要意义。近年来，随着医疗技术不断进展，胰岛素泵注射逐渐步入临床，且被众多学者应用，临床已证实效果显著，有助于更好的控制血糖[3]。鉴于此本文选取92例GDM患者采用上述治疗方式进行研究，现报道如下。

1 资料与方法

1.1一般资料

选取2017年1月～2……