68例心肺复苏术后患者生命支持治疗效果分析
2020-08-13陈兰春杜慧君唐玮欣
陈兰春 杜慧君 唐玮欣


【摘要】 目的 分析心肺復苏术(CPR)后患者实施生命支持的情况及其效果, 为下一步提出改进措施提供依据。方法 回顾性分析68例CPR后患者的临床资料, 根据预后神经功能恢复情况将患者分为A组(不良神经功能结局组, 55例)和B组(良好神经功能结局组, 13例)。分析比较两组患者的一般资料、各项生命支持治疗情况、体温及院外心脏骤停(OHCA)和院内心脏骤停(IHCA)发生情况。结果 两组患者的性别、年龄比较差异无统计学意义(P>0.05)。68例患者CPR后24 h内最高体温为(37.3±1.5)℃, 其中29例(42.6%)体温>37.5℃;CPR后7 d内最高体温为(38.0±1.5)℃, 其中36例(52.9%)出现中度发热(腋温>38.0℃)。良好神经功能结局组患者CPR后24 h内最高体温为(37.6±0.7)℃, 与不良神经功能结局组的(37.3±1.6)℃比较, 差异无统计学意义(t=0.658, P=0.513>0.05)。良好神经功能结局组患者中, OHCA患者3例(23.1%), IHCA患者10例(76.9%);不良神经功能结局组患者中, OHCA患者14例(25.5%), IHCA患者41例(74.5%);两组患者OHCA和IHCA发生情况比较, 差异无统计学意义(P>0.05)。结论 虽然对心脏骤停(CA)行CPR后患者实施了各种生命支持措施进行综合救治, 但其死亡率仍然很高。早期体温管理尚有待进一步加强与规范, 院前急救时及早建立人工气道可能有助于改善预后。
【关键词】 心脏骤停;心肺复苏术;生命支持;预后
DOI:10.14163/j.cnki.11-5547/r.2020.20.012
【Abstract】 Objective To analyze the status of life support treatment on patients after cardiopulmonary resuscitation (CPR), so as to provide the evidence for further improving. Methods A total of 68 patients after CPR were divided into poor neurological outcome group (55 cases) and good neurological outcome group (13 cases) by recovery of neurological function. The general data, life support treatment status, body temperature, and occurrence of out-of-hospital cardiac arrest (OHCA) and in-hospital cardiac arrest (IHCA) were analyzed and compared between the two groups. Results There was no statistically significant difference in gender and age between the two groups (P>0.05). The highest temperature of 68 patients within 24 h after CPR was (37.3±1.5)℃, of which 29 cases (42.6%) had a temperature>37.5℃; the highest temperature within 7 d after CPR was (38.0±1.5)℃, of which 36 cases (52.9%) had moderate fever (axillary temperature>38.0℃). The highest body temperature of good neurological outcome group within 24 h after CPR was (37.6±0.7)℃, which had no statistically significant difference compared with that of patients with poor neurological outcome group (37.3±1.6)℃ (t=0.658, P=0.513>0.05). In good neurological outcome group, there were 3 patients with OHCA (23.1%), 10 patients with IHCA (76.9%); In poor neurological outcome group, there were 14 patients with OHCA (25.5%), 41 patients with IHCA (74.5%). There was no statistically significant difference in the occurrence of OHCA and IHCA between the two groups (P>0.05). Conclusion Although patients underwent comprehensive life support measures after CPR for cardiac arrest (CA), the mortality rate is still high. Early body temperature management needs to be further strengthened and standardized, and early artificial airways in pre-hospital rescue maybe improve the prognosis of CA patients eventually.
【Key words】 Cardiac arrest; Cardiopulmonary resuscitation; Life support; Prognosis
近年发布的心肺复苏术(cardiopulmonary resuscitation, CPR)指南, 对规范和推广心脏骤停(cardiac arrest, CA)现场CPR及后续高级生命支持治疗具有重要的指导价值, 特别对基层医院帮助更大。但目前CA患者的死亡率仍居高不下, 国外报道院外心脏骤停(out-of-hospital cardiac arrest, OHCA)出院存活率仅为10%~12%, 院内心脏骤停(in-hospital cardiac arrest, IHCA)为15%~20%[1, 2], 国内报道<10%[3, 4]。如何提高CA患者抢救成功率, 仍然是当今医学界的一大难题。为了解本科CPR后各项生命支持措施实施现状及其效果, 探讨改进措施, 作者对2014年1月~2018年12月的68例CPR后患者, 在重症监护病房(ICU)住院期间各种生命支持措施的实施情况及其对预后的影响进行回顾性分析。现报告如下。
1 资料与方法
1. 1 一般资料 回顾性分析本院2014……
