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KEYWORD INDEX(2020,Volume 36)

2020-01-13

中国病理生理杂志 2020年12期

20-Hydroxyeicosatetraenoic acid 421

2019 novel coronavirus/SARS-CoV-2 562

27nt-miRNA 1745

ABCA1/JAK2/STAT3 signaling pathway 1972

Abdominal aortic aneurysm 769

Activation 1396

Activity regulation 2289

Acute cardiogenic pulmonary edema 1255

Acute cerebral ischemia 1389

Acute hepatic injury 860

Acute kidney injury 188 294 525 1450 2081

Acute lung injury 507 681 725 913

Acute lymphoblastic leukemia 977 1776

Acute myocardial infarction 415

Acute respiratory distress syndrome 562 568

Acyl-coenzyme A:cholesterol acyltransferase 1 816

Adipocytes 134

Adiponectin 796

Adipose differentiation 899

Adipose tissue 2099

Adrenergic signaling 747

Adriamycin/doxorubicin 1543

Aging 936

Agkistrodon acutusvenom 991

Airway inflammation 886

Akt signaling pathway 552

AKT/NF-κB signaling pathway 427

AKT/STAT3 singaling pathway 612

Albumin 681

Alcohol 969

Allele 354

Alpiniae oxyphyllaeFructus 2212

Alveolar type Ⅱepithelial cells 1825

Alzheimer disease 1063 2198

AMP-activated protein kinase 796 936

AMPK/Nrf2/HO-1 signaling pathway 38

AMPK/TFEB signaling pathway 1269

Amyolid β-protein 1-40 1966

Anacardic acid 200

Andrographolide 628 977

Anesthesia depth 475

Angiogenesis 969 1422 1515

Angiotensin Ⅱtype 1 receptor autoantibody 444

Anhua dark tea 1274

Anthocyanin 360

Anti-silencing function 1B 1602

Anti-tumor drugs 1133

Apelin-13 134

Aplastic anemia 1314

Apolipoprotein E 1274

Apoptosis 22 29 38 59 67 97 152 170 206 214 222 229 239 244 329 366 401 421 433 444 487 525 628 657 673 707 753 788 847 977 985 991 1006 1055 1082 1089 1110 1185 1199 1237 1368 1375 1404 1413 1450 1493 1616 1653 1745 1761 1776 1860 1928 1945 2005 2013 2043 2166 2212 2234

ARMCX1 protein 170

Arteriogenesis 1537

Arthritis 693

Asthma 886 1465 1502 1715 1818

Astragaloside 2244

Astragalus2198

Astrocytes 501 1042

ATAC-seq 2037

ATF6/PERK-CHOP signaling pathway 1006

Atheroscherosis 637 713 816 1020 1261 1327 1476 1515 1565 1754 1897

Atherosclerosis 1928 1952 2093 2123 2133

ATM protein 741

ATP-binding cassette transporter A1 816 1952

ATP-binding cassette transporters 206

ATR protein 741

Atrial natriuretic peptide 47

Autism 837

Autoimmune myocarditis 1729

Autophagy 366 444 673 725 796 860 893 924 936 1014 1071 1199 1230 1269 1428 1439 1444 1493 1616 1825 1980 2020 2056 2081

Autophagy-related protein 5 847

B-lymphocyte stimulator 1294

Bacterial meningitis 1161

Baicalin 268 1294

Batokines 1140

Bcl-2 protein 2005

Bcl-6 protein 2205

Belinostat 552

Bexarotene 1565

Bezafibrate 519

Bile acids 2086

Bioinformatics 175 346 998 2037

Biological behavior 1587

Biomarkers 2264

BIRC5 protein 2013

Bladder cancer 82 612

Bladder detrusor 2212

Bladder outlet obstruction 301

Blood dialysis 562

Blood-brain barrier 2190

Blueberry 360

BMP-7/Smads pathway 316

Body weight 1921

Bone marrow mesenchymal stem cells 762

Bortezomib 1482 2062

Brain injuries 468

Brain-derived neurotrophic factor 282

Breast cancer 244 865 969 1587 1595

Bronchial epithelial cells 507 557

Brown adipose tissue 1140

BTB and CNC homology 2 1776

Burn 336

Bushen-Huoxue prescription 700

c-Met/AKT/mTOR signaling pathway 871

c-Myc protein 234

C1GALT1/Cosmc pathway 2050

C1q/TNF-related proteins 1470

C1q/tumor necrosis factor-related protein 3 1551

C57BL/6 mice 1146

Calcium channels 2212

Calcium ion 532

Calcium phosphate 769

Calcium-activated chloride channel 2105

Calpain-2 847

Capsular polysaccharide 514

Carboxyl terminus of heat shock protein 70-in⁃teracting protein 1368

Cardiac contractility modulation 547

Cardiac fibroblasts 1 1543

Cardiac fibrosis 1 385 1531 1521

Cardiac hypertrophy 1122

Cardiac remodeling 2113

Cardic myocytes 433

Cardiomyocyte hypertrophy 200

Cardiomyocytes 214 401 421 788 796 1014 1761

Cardiopulmonary resuscitation 468

Cardiovascular diseases 371

Cartilage degeneration 700

Caspase-1 598

Catalase 1302

Cathepsin C 2133

Caveolin-1 2123

CC chemokine receptor 2 969

CC-223 234

CCAAT/enhancer-binding protein homologous protein 222

CCDC78gene 998

CCN proteins 1902

CD36/Src/ERK signaling pathway 1020

CD68 1557

Celastrol 487

Cell cycle 164 234 495 707 1572 1579 1595

Cell differentiation 762 1988

Cell growth 977

Cell invasion 252 2174

Cell migration 252 619 810 871 1170 1192 1215 1224 1434 1487 1579 1887 2166 2174

Cell proliferation 59 152 164 170 239 276 810 871 1071 1170 1396 1422 1595 1680 1690 1988 2005

Cell viability 67 97 244 252 276 479 552 619 906 985 1082 1487 1572 1579 1602 1776 1789 1887 1945 2013 2043 2166 2174

Cellular senescence 652

Cerebral cortical nerve cells 673

Cerebral ischemia-reperfusion 673 2190 2251

Cerebrospinal fluid 1875

Cervical cancer 67 170 1439

Cervical squamous intraepithelial lesions 2300

Cervical squamous-cell carcinoma 146

Chaihu-Shugan decoction 1476

Chemerin 1122

Chemotherapy 175

Chloroquine 1320

Cholangiocarcinoma 961

Cholesterol 53 1359

Cholesterol efflux 1980

Chondrocytes 1089

Choroidal neovascularization 104

Chronic heart failure 547

Chronic hepatitis B 1833

Chronic intermittent hypoxia 1631

Chronic kidney disease 188

Chronic obstructive pulmonary diseases 1302

Chronic periodontitis 1308

Chronic unpredictable mild stress 451

Circular RNA 688

Circular RNA_0000231 239

Circular RNA_001131 1

ClC-3 channel 1153

ClC-3 chloride channel 495

Clear cell renal cell carcinoma 1996

Clinical application 1133

Cluster of differentiation 14 539

Cluster of differentiation 36 1269

Co-stimulatory molecules 1314

Cognitive dysfunction 1810

Collagen type I alpha 1 chain 59

Colon cancer 175

Colorectal cancer 998 1215

Complement 1115 1960

Connexin 43 501 547

Continuous renal replacement therapy 2081

Cordyceps militarispolysaccharides 1754

Coriaria sinicaMaxim´s extract 336

Coronary artery 439

Coronary artery atherosclerosis 1557

Coronary artery disease 206

Coronary atherosclerotic heart disease 1255 1470

Coronary heart disease 408 2133

Coronavirus disease 2019 568 573 1913

Coxsackie virus B3 427

CR6-interacting factor 1 401

CREB/BDNF signaling pathway 1063

Cromolyn sodium 693

Crush injury syndrome 2220

Cucurbitin E 886

Cumulus cells 2294

Cuprizone 1115

Curcumin 860 1647 1867 2056

CXC chemokine receptor 7 612

Cyanidin 2113

Cyclin D1 239

Cycloastrogenol 385

Cyclooxygenase-2 2159

Cystathionine β-synthase 119

Cysteine-rich protein 61 507

Cytochrome b-245 alpha polypeptide 1302

Cytochrome P450 epoxygenases 1661

Cytokine storm 568 1913

Cytokines 514

Dasatinib 2166

Deacetylation 1334

Decellularized scaffold 762

Demyelinating diseases 1115

Dendritic cells 2093

Dendritic spines 1049

Deoxyribonuclease 913

Depression 282 451 461 1049 1875 2264

Dexmedetomidine 282 1185

Diabetes mellitus 38 433 598 930 1368

Diabetic cardiomyopathy 29 47

Diabetic hepatopathy 519

Diabetic kidney disease 1696

Diabetic nephropathy 53 893 1639

Diabetic retinopathy 577 1382 1515

Differentiation 1020

Dihydroartemisinin 1782

DNA damage 487

DNA damage repair 1667

DNA damage response 741

DNA double-strand breaks 741

DNA methylation 119

DNA-dependent protein kinase 741

Dopamine 289

Dopaminergic neurons 127

Dorsal root ganglion 1153

Double-edged sword 725

Doxorubicin 552

Drug development 1133

Drug resistance 89 175

Drug treatment 1502

Dynamin-related protein 1 47 1110

E-cadherin 1434

E3 ubiquitin ligase ITCH 930

Eca109 cells 1690

Elderly patients 475

Electrical remodeling 547

Electro-acupuncture 1972

Elemene 707

End-stage renal disease 2068

Endocrine 1140

Endogenous cannabinoids 2020

Endometrial cancer 2174

Endometriosis 1892

Endoplasmic reticulum stress 9 193 222 847 936 991 1006 1027 1071 1237 1375 2020

Endothelial cells 17 652 713 1006 1351 1515 1537 2276

Endothelial nitric oxide synthase 803 1739

Endothelial-mesenchymal transition 316 893

Endothelial-to-mesenchymal transition 822

Endothelin receptors 779

Endothelium-dependent relaxation 2159

Endotoxin 294

Enterohepatic circulation 2086

Eosinophils 1818

EphB2/ephrin-B1/NMDA receptor signaling pathway 1389

Epidermal growth factor receptor 514

Epidermis 753

Epigallocatechin gallate 1769

Epigenetics 1327 2099

Epimedium2198

Epithelial cells 2276

Epithelial sodium channel 943

Epithelial-mesenchymal transition 479 1422 1608

Epoxyeicosatrienoic acids 1661

Epstein-Barr virus 2030

ERK1/2 signaling pathway 1224

Erythroid differentiation 663

Esophageal cancer 97 1690

Esophageal carcinoma 75

Esophageal squamous-cell carcinoma 1192

Estriol 1281

Ethyl pyruvate 2182

Eukaryotic expression 1071

Excitotoxicity 2182

Exenatide 1921

Exosome 371 378

Exosomes 606 906 1014 1351 2074

Experimental autoimmune encephalomyelitis 181

Expression regulation 2289

Extracellular matrix 719 762 1531

Extracts of Herba Taxilli 1082

F-box and WD repeat domain containing pro⁃tein 7 2234

Farnesoid X receptor 2086

Fasudil 1796 1803

Fatty acid synthase 289 1892

Fecal microbiota transplantation 1833

Fenglong point 1972

Ferroptosis 1261

FEZF1-AS1 1945

FHITgene 1493

Fibroblast growth factor 9 214 1653

Fibroblasts 2043

Fibronectin 157

Fibrosis 1458 1543

Finasteride 323

Fine particulate matter 810

Flax lignan/secoisolariciresinol diglucoside 1631

Flow cytometry 1396

Foam cells 816 1230 1897 1980

Forkhead box protein O1 294

Formononetin 1434

Forsythiaside A 1128

FRT cells 2105

Fructose 735

Fucosylation 1192

Fuzilizhong decoction 2258

G-protein-coupled receptor 75 421

Gabexate mesilate 2190

Galectin-3 1557

Galectin-9 1308

Gastric cancer 152 2005 2013

Gastric carcinoma 2030

GATA binding protein-1 663

GATA binding protein 5 415

Gene chips 175

Geniposide 1810

Genomic instability 1493

GINS complex subunit 2 2043

Glioma 707 1887

Glomerular epithelial cells 1860

Glucagon-like peptide-1 1921

Glucogen sythase 1769

Glucose metabolism 1515

Glucose transporter 2 1769

Glucose-6-phosphate dehydrogenase 1769

GlutathioneS-transferase kappa 1 1996

Glycolipid metabolism 735

Glycolysis 1572

Golden hamsters 140

Granulosa cells 2234

Granulosa cells 2294

Gynostemma pentaphyllum 713

H19gene 2030

H9C2 cells 444 1122 1249

HaCaT cells 1854

Heart 1237

Heart failure 924 1034 1509 1938

Heart function 1531

Heat shock protein 90 1960

Heat shock protein 90α 157

Hedgehog signaling pathway 700

Hemorrhagic shock 2074

Hepatic fibrosis 719

Hepatic injury 119

Hepatic stellate cells 688 719

Hepatitis B virus 1281 1721

Hepatocellular carcinoma 252 1207 1487 1782 2283

Hepatocytes 847

Hepcidin 2198

HET 0016 1170

Heterodimer 1729

High glucose 788 1608 2159

High glucose and high free fatty acid 29

High mobility group protein B1 1639

High-density lipoprotein 206

High-density lipoprotein cholesterol 1255

High-mobility group protein B2 164

High-throughput screening 2105

Hippocampus 1049 1185 1389

Hippocampus 461

Histone acetylation 200

Histone chaperones 1602

Histone deacetylase 6 1334

Histone deacetylases 557 2099

Histone H3K36 trimethylation 525

Histone methylaion 719

Homocysteine 119

Hormone-sensitive lipase 289 899

HOTAIRgene 2030

hsa-miR-145-5p 1413

hsa-miR-346 2205

hsa_circ_087631 2205

HSYA 439

HT22 cells 2198

Human aortic endothelial cells 1928

Human gingival fibroblasts 1867

Human hemangioendothelial cells 1422

Human induced pluripotent stem cells 877

Human papillomavirus 2300

Human peritoneal mesothelial cells 2068

Human umbilical vein endothelial cells 193 822 1368 1739 1745

Human vascular smooth muscle cells 810

HuR protein 2283

Hydrogen sulfide 652

Hyperbaric oxygen 1063

Hyperlipidemia 140 1972

Hyperpolarization-activated cyclic nucleotidegated cation channels 827

Hypertension 1345 1938

Hyperthyroidism 1625

Hyperuricemia 1551

Hypoxemia 568 573

Hypoxia 214 244 663 1351

Hypoxia-hypercapnia pulmonary hypertension 316

Hypoxia-inducible factor-1α 244 1537 1661

Hypoxia/reoxygenation injury 1825

Hypoxic ischemic encephalopathy 366

Hypoxic postconditioning 1960

Hypoxic-ischemic encephalopathy 2182

Idiopathic pulmonary fibrosis 112

IgA nephropathy 2050

IGF-1R-Stat3 signaling pathway 1207

IL-33/ST2 signaling pathway 468 2062

IL-6/STAT3 signaling pathway 97

Ilex cornutaaqueous extract 899

ILK signaling pathway 336

Immune 1340

Immune function 1128 2050

Immune imbalance 1913

Immune inhibitory receptor 1314

Immune response 394

Immunomodulation 1465

Inducible nitric oxide synthase 2159

Indxyl sulfate 1014

Infertility 2234

Inflammation 22 53 104 112 301 309 854 913 1104 1185 1320 1551 1639 1647 1661 1960 1966 2062 2190 2258

Inflammatory bowel disease 1096

Inflammatory cytokines 1704

Inflammatory factor 354

Inflammatory factors 157 693 1844 2081

Inflammatory response 427 507 514 557 637 681 1128 1625 1867

Inflarnmation 1465

Influenza A virus 1673

Influenza virus 681

Inositol 1,4,5-trisphosphate receptor 532

Insulin 2139

Insulin resistance 588 930 1661

Insulin-like growth factor 1 receptor 1215

Insulin-like growth factor 2 mRNA-binding pro⁃tein 3 75

Insulin-producing cells 877

Interferon gamma 1096

Interleukin-1 receptor accessory protein 1729

Interleukin-1 type II receptor 1729

Interleukin-10 1153

Interleukin-11 1531

Interleukin-17 1096

Interleukin-17A 1854

Interleukin-18 1833

Interleukin-1β 1082 1739

Interleukin-21 2205

Interleukin-33 1450

Interleukin-38 1715

Interleukin-4 539

Interleukin-6 779

Intermittent hypoxia 2212

Interstitial lung disease 1715

Intestinal barrier injury 1844

Intestinal fibrosis 1096

Intestinal flora 2050

Intracerebral hemorrhage 1055

Invasion 82 619 1192 1215 1224 1434 1579 1680 1789 1881 1887

IOX1 719

Ischemia-reperfusion 394

Ischemia/reperfusion 525 644

Ischemia/reperfusion injury 329 1960 2093

Ischemic stroke 1709

Isolated heart perfusion 1243

Isolationin vitro2294

Jieyuwan 1049

Jinlida 1375

Junctophilin-2 1034

K562 cells 663 1988

Kechuanning 1465

Keloid 2043

Keratinocytes 753

Ketamine 1042

Kidney diseases 378

Kidney injury 1625

Kidney proximal tubular cells 1104

Klebsiella pneumoniae 514

KLF6gene 97

Klotho protein 816

Knee osteoarthritis 157 700

Krüppel-like factor 1 360

Kupffer cells 854

LH-EGFR signaling pathway 532

Ligustilide 1422

Linc00152 67

LINC01503 619

Lipid metabolism 588 637 1261

Lipids 1921

Lipoic acid 127

Lipophagy 1980

Lipopolysaccharide 1860 1867

Lipopolysaccharides 507 837 1320

Liraglutide 588

Liver fibrosis 360 688

Liver X receptor α 1359

Local anesthetic 1667

Long noncoding RNA 1761 1789 1908 1945 2030

Long noncoding RNA ANRIL 1404

Long-chain non-coding RNA MALAT1 82

LoVo cells 479

Low-density lipoprotein receptor 140

Low-polarity ginsenoside F41988

Lung adenocarcinoma 164 1680 1789 1881

Lung cancer 619 985 1579 1715

Lung cancer-associated transcript 1 1761

Lung injury 309

Lung ischemia/reperfusion injury 2056

Lupeol 1413

Lupus nephritis 188 1146 1647

Lycorine 479

Lysosome 1359

M2 macrophage polarization 961

Macrophage polarization 104

Macrophage-derived foam cells 1754

Macrophages 769 906 1014 1020 1308 1359 1897 1952 1972 1980

Mailuoning 2220

Mammalian target of rapamycin 234

Mangiferin 657

MAP4K3/MKK4/JNK signaling pathway 1055

MAPK signaling pathway 886 1320

MAPK/ERK signaling pathway 479

MAPK/JNK/ERK signaling pathway 1602

MAPKs signaling pathway 1966

Mast cells 693

Maternal immune activation 837

Matrix metalloproteinase-1 268

Matrix metalloproteinase-2 1557

Matrix metalloproteinase 9 769 1434 1892

Mechanical allodynia 1153

Melanoma 606

Melusin 408

Mesenchymal stem cells 2037

Mesenteric lymph 2074

Metabolic diseases 735 1140

Metabolic pathways 1526 2264

Metabolism 1327 1509

Metabolomics 1526 2264

Metastasis 146

Metformin 495

Methicillin-resistantStaphylococcus aureus1673

Mice 519 753

Microglia 127 837 1170 1320

MicroRNA 175 371 378

MicroRNA let-7a 1055

MicroRNA-124 1867

MicroRNA-133 854

MicroRNA-142-3p 1928

MicroRNA-146b-5p 82

MicroRNA-153 22

MicroRNA-153-3p 1249

MicroRNA-16 1875

MicroRNA-19b 2139

MicroRNA-204-3p 1761

MicroRNA-206 871

MicroRNA-214-5p 394

MicroRNA-22 1014

MicroRNA-22-3p 2068

MicroRNA-223 1482

MicroRNA-223-3p 1161

MicroRNA-23b-3p 1653

MicroRNA-24-3p 97 865

MicroRNA-25-3p 1

MicroRNA-3 1721

MicroRNA-301a-3p 501

MicroRNA-30a-5p 119

MicroRNA-323 214

MicroRNA-335-5p 619

MicroRNA-363-3p 1945

MicroRNA-375 877 1082

MicroRNA-376c-3p 67

MicroRNA-424-3p 1487

MicroRNA-432-3p 657

MicroRNA-433 1458

MicroRNA-451a 663

MicroRNA-485-5p 252

MicroRNA-519d-3p 1789

MicroRNA-556-3p 2174

MicroRNA-626 1404

MicroRNA-7-5p 1860

MicroRNA-9-5p 2148

MicroRNA-92a 2139

MicroRNA-92b-5p 1639

Microvascular permeability 644

Midkine 1207

Mifepristone 89

Migration 82

MIN6 cells 2139

Minimally modified low-density lipoprotein 779

Mitochondria 924 1110

Mitochondrial autophagy 2251

Mitochondrial calcium uniporter 433

Mitochondrial damage 1696

Mitochondrial division inhibitor-1 1115

Mitochondrial dysfunction 366 421 1122

Mitochondrial energy metabolism 713

Mitochondrial fission 47

Mitochondrial fusion 2113

Mitochondrial injury 294

Mitochondrial membrane potential 487 977

MNX1 antisense RNA 1 1908

Monocyte chemoattractant protein-1 969

Monocytes 1255 1482

Monocytes/macrophages 1327 1521

Morphine 9

Mortalin 146

Mouse embryonic fibroblasts 606

Multiple myeloma 487

Multiple sclerosis 181

Myeloid differentiation factor 88 1450

Myeloperoxidase 309

Myocardial cells 657

Myocardial dysfunction 1243

Myocardial fibrosis 1938

Myocardial infarction 644 1027 1521 2093

Myocardial injury 22 38 394 573

Myocardial protection 9

Myocardial remodeling 2093

Myocardin-related transcription factor-A 673

Myocardium 408

N-arachidonic acid aminoethanol 2020

N-palmitoylethanolamine 451

NADPH oxidase 4 577

Nasopharyngeal carcinoma 346

Nasopharyngeal carcinoma cells 495

Natural killer T cells 1345

Necroptosis 1104

Necrotizing enterocolitis 2227

Neonatal rat 1796

Neoplasm invasion 1493

Nesfatin-1 2227

Neural stem cells 1396

Neurogenesis 1389

Neurons 827 1055 1161

Neurons 366

Neuropathic pain 1153

Neuropeptides 693

Neuroprotection 1709

Neurotoxicity 1667

Neurovascular unit 1709

Neutrophil extracellular traps 913

NF-κB P65 signaling pathway 1690 1796

NF-κB signaling pathway 557 886 1104 1170 1320 1647

NF-κB/cyclin D1 signaling pathway 1595

Nicotine 104 1287

Nicotinic acetylcholine receptors 1287

Nicotinic acid 1359

Niemann-Pick C1 protein 1359

Niflumic acid 1887

Nintedanib 112

Nitric oxide 17

NLRC3 protein 985

NLRP3 inflammasome 181 309 577 936 1161 1631 1673

NLRP3 protein 53

NLRP3 signaling pathway 1647

NLRP3/IL-1β signaling pathway 1089

Non-alcoholic fatty liver 1274 1902

Non-alcoholic fatty liver disease 588 2258

Non-small-cell lung cancer 239 1224

NontypeableHemophilus influenzae557

Notch signaling pathway 260 2220

Nrf2/ARE signaling pathway 1249

Nrf2/ARE/HO-1 signaling pathway 2182

Nuciferine 1230

Nuclear factor E2-related factor 2 29 657

Nuclear factor-κB 385 2159

Nuclear factor-κB-inducing kinase 1302

Nuclear translocation 1269

Nucleotide-binding oligomerization domainlike receptor protein 3 854 1482 2068

Obesity 899 1140 1661 1902 2234

Obesity-related kidney disease 188

Obstructive nephropathy 301

Olapanib 89

Oligodendrocytes 1115

Oncolytic virus M1 950

Oocyte meiosis 532

Oocytes 918

Optic atrophy protein 1 2113

Organic solute transporter α/β 2086

Osteoarthritic chondrocytes 1082

Osteoarthritis 1089

Osteoblasts 598

Osteogenic differentiation 2037

Osteoporosis 598

Osteosarcoma 552 628

Ovarian cancer 59 229 1434 1428 2020

Ovarian epithelial cancer 89

Oxidative damage 1274

Oxidative stress 9 29 38 112 134 193 385 401 444 568 1249 1368 1404 1509 1616 1625 1631 1761 1860 2056 2190 2244

Oxidized low-density lipoprotein 1230 1327 1745 1897

Oxygen-glucose deprivation/reoxygenation 1178

P-selectin glycoprotein ligand-1 188

p16 protein 2300

p21-activated protein kinase 4 394

P2Y2purinergic receptor 2105

p38 MAPK signaling pathway 53 200 779 810

P65 protein 1938

Paeonol 1487 1854

Pain 693

Palmitic acid 401 803

Palmitoylation 1269

Panax notoginseng saponins 140 1178

Panc-1 cells 1199

Pancreatic ductal adenocarcinoma 260

Pancreatic fibrosis 268

Pancreatic kininogenase 1616

Pancreatic progenitor cells 276

Pancreatic stellate cells 260

Papillary thyroid carcinoma 871

Paracellular pathway 2276

Paraventricular nucleus 2148

Parkin 2251

Parkinson disease 127 289 1042 1404

Particulate matter 2.5 1526

Pathogenesis 2264

PD-L1 protein 1704

Perfluorooctane sulfonates 309

Periapical diseases 539

Perilipin 1 899

Perilipin 3 1881

Perioperative neurocognitive disorders 1185

Peritoneal dialysis 2068

Periventricular leukomalacia 1796

PERK signaling pathway 9

PERK/eIF2α singaling pathway 991

Peroxisome proliferator-activated receptor α 451

Peroxisome proliferator-activated receptor-γ 637 899 1608

Peroxisome proliferator-activated receptors 519 1509

Phenotypic switching 1966

Phenotypic transformation 1345

Phenylephrine 200

Phosphatidylinositol 3-kinase 2289

Phosphoglycerate mutase family member 5 1110

Phospholipase A2-X 1818

Phosphorylation 803 1739

PI3K/AKT signaling pathway 336 788 1487 1782

PI3K/AKT/mTOR signaling pathway 282 329 1199 1230 1428

Pim1/eNOS signaling pathway 17

Pinocembrin 1006

Pirfenidone 112

Plaque stability 1557

Platelet-derived growth factor receptor α 918

Platelet-derived growth factor receptor β 1345

Platelet-derived growth factor subunit A 918

Platelet-rich plasma 1089

Polycystic ovary syndrome 906 2244

Porphyromonas gingivalis 1867

Post-operative cognitive dysfunction 475

Postmenopausal women 1255

PPARγ-LXRα-ABCA1/ABCG1 signaling path⁃way 1754

Precise quantification 1721

Prefrontal cortex 451 1049

Premature infants 2227

Premature labor 1803

Prenatal exposure 323

Primary biliary cholangitis 2205

Primary culture 753 2294

Primer probe 1721

Pristane 1146

Procaine 612

Prognosis 146 1881 2013 2081

Proliferating cell nuclear antigen 1892

Promoter 415

Proprotein convertase subtilisin/kexin type 9 140

Prostaglandin E1 1027

Prostate cancer 1572 1602

Prostate carcinoma 1413

Protein kinase B 652

Protein phosphatase 2A 803

Protein phosphatase 4 803

Protocadherin 10 1595

Psoriasis 1854

PTEN protein 1608 2289

PTEN-induced putative kinase 1 2251

Pterostilbene 1439

Pulmonary artery endothelial cells 316

Pulmonary edema 562

Pulmonary hypertension 1302

Pulsatilla saponin A 865

Purple sweet potato anthocyanin 1844

Pyroptosis 301 598 1178

Pyruvate dehydrogenase kinase 4 1572

Quantitative acetylproteomics 1996

Quercetin 644 2251

Quiescence 1396

Rab11-family interacting protein 4 1215

Radiosensitivity 67 707 865

Radiotherapy 1782

RadixPuerariae2198

Randomly arranged collagen fibers 762

Rapamycin 1709

Raphe nuclei 1875

RAS signaling pathway 1587

Ras-relate C3 botulinon toxin substrate 1 606

Rats 360 1128 1237

Reactive oxygen species 433 577

Receptor-interacting protein 1 1104

Receptor-interacting protein 2 1199

Recombinant adeno-associated virus serotype 9 1938

Recombinant human progranulin 1071

Regional cerebral oxygen saturation 475

Regression analysis 408

Regulatory T cells 1913

Relaxation 439

Renal cancinoma 2166

Renal fibrosis 188 1616

Renal inflammatory injury 1631

Renal interstitial fibrosis 893

Renal microvascular endothelial cells 1375

Renal tubular epithelial cells 294 1608

Renin-angiotensin system 134

Replication 1281

Reproductive health 1340

Reproductive organs 323

Respiratory diseases 943

Resveratrol 229 893 1161

Retinoic acid X receptor 1825

Retinoid X receptor α 1565

Retroperitoneal white adipose tissue 289

Reverse cholesterol transport 1754 2123

Rheumatoid arthritis 354 1294 1482 1653 2062

Rho-associated coiled-coil kinase 788

Rho/ROCK signaling pathway 1803

Rho/ROCK2 signaling pathway 1796

Rictor 1928

Ring finger protein 2 865

RNA interference 276

RNA-binding proteins 2283

ROCK/JNK signaling pathway 1476

RT-qPCR 950 1721

SARS-CoV-2 1340 1913

SASH1 protein 2174

SATB1 protein 346

Scavenger receptors 1897 1952

Scutellarin 1860

Secondary pneumonia 1673

Semaphorin 4D 1465

Sepsis 1243 1450 1945

Serotonin transporter 1875

Serum and glucocorticoid-regulated kinase 1 301

Sex determining region Y-box 5 252

Sex hormones 2244

Sexual developmental disorder 323

SH-SY5Y cells 1178

Shear stress 17

SHI-1 cells 1988

Signal transducer and activator of transcription 3 276

Signaling pathways 1696

SiHa cells 170

Silent information regulator 1 644

Simvastatin 1690

Single nucleotide polymorphism 354 415 1302 2030

Sinomenine 1404 1653

SIRT1-FoxO signaling pathway 1439

SIRT1/AMPK signaling pathway 588

Sirt3-SOD2-ROS signaling pathway 229

Skeletal muscle 1921

Sleep deprivation 1810

Smad3 protein 822

Small-conductance calcium-activated potassium channels 2148

Soluble uric acid 1444

Sorafenib 222

SORBS2 protein 22

Sperm 1340

Spermatogenesis 323

Sphingosine 1-phosphate 822

Sphingosine kinase 1 1224

Spinal cord injury 461

Spinal dorsal horn 827

Spleen tyrosine kinase 961

Splicing factor 3B subunit 1 1587

Spontaneously hypertensive rats 1476

Stanniocalcin-1 2005

Stanniocalcin 2 1382

STAT3 singaling pathway 1854

Stellate ganglion block 2074

Stem cells 1287

Stemness 89

Sterile inflammation 1543

Stress 747

Suberoylanilide hydroxamic acid 222

Substrates 1334

Sulodexide 577

SUMO-specific protease 3 769

Survivin 234

Susceptibility 415 2030

Swimming 1892

Sympathoexcitation 2148

Synapses 461

Synaptic damage 1063

Synoviocytes 1653

SYNTAX score 1255

Systemic lupus erythematosus 1146

T helper 17 cells 1913

T-cell immunoglobulin and mucin domain-con⁃taining protein-3 1308

T-tubule 1034

Tandons 762

Tanshinone ⅡA 1261

TaqMan 950

Targeted therapy 961

Testicular torsion 329

Testis 1340

Tetrandrine 1428

TGF-β1/SMAD2 signaling pathway 1458 1565

TGF-β1/Smads signaling pathway 688

TGF-β1/TAK-NF-κB signaling pathway 268

Th17 cells 1294

The Cancer Genome Atlas 998

Theca cells 906

Thermogenesis 2099

Thioredoxin 681

Thioredoxin-interacting protein 1631

THP-1 cells 1020

Tight junction 2276

Tight junction protein 1844

Tissue Doppler imaging 1243

Tissue inhibitor of metalloprotease-1 268

TLR4/NF-κB p65 signaling pathway 2258

TLR4/NF-κB signaling pathway 1810

TMT-tagged quantitative proteomics 346

Toll-like receptor 4 637 837 1444 1551 1833 2227

Tongue squamous carcinoma 991

Tongxinluo 1375

Trained immunity 1327

Transcription 1281

Transcription factor 735

Transcriptional intermediary factor 1γ 1579

Transcriptional regulation 735

Transforming growth factor-β 385 822

Transforming growth factor-β1 336

Transient receptor potential cation channel sub⁃family M member 8 1680

Transient receptor potential cation channel sub⁃family V member 1 1502

Transverse aortic constriction 2113

Trauma 1237

Tricellulin 2276

TrimethylamineN-oxide 193 1034

Tripartite motif-containing protein 25 75

Tripartite motif-containing protein 8 29

Tripterine 2043

Tripterygium wilfordiimultiglucoside 2050

Tropomyosin-related kinase B 282

TSTA3 protein 1192

TTN antisense RNA 1 1789

Tuberculosis 1715

Tubular epithelial cells 1444

Tubulin 1034

Tumor 747 1515 1908

Tumor immune 1704

Tumor microenvironment 1704

Tumor necrosis factor ligand-related molecule 1A 1096

Tumor necrosis factor-α 539 1153 2133

Tumor xenograft model 1133

Type 2 diabetes mellitus 1470 1769 2148

Ubiquitin proteasome system 930

Ubiquitination 75

Ulcerative colitis 1128 1844

Umbilical cord mesenchymal stem cells 1351

Unilateral ureteral obstruction 1616

Uremia 1014

Uric acid 134 1110

Urine 378

Vascular endothelial cells 1551 1945

Vascular endothelial growth factor 1382 1422

Vascular smooth muscle cells 1345 1565 1966

Vasculitis 573

Ventricular remodeling 1027

Viral myocarditis 427

Voltage-gated K+channels 439

Voltage-gated sodium channels 1153

Water-salt balance 943

Wendan decoction 1952 2123

White matter injury 1803

Wnt signaling pathway 628

Wnt/β-catenin signaling pathway 2220

Wogonoside 427

Xingnao enema fluid 468

Xuebijing 329

Yangjing-Zhongyu decoction 918

Yes-associated protein 1537

Youguiwan 157

Zebrafish 1133

α-Synuclein 1042

β1,3-N-actetylglucosaminyltransferase 8 152

β1-Adrenergic receptor autoantibody 796