董慧芹

【摘 要】目的：探究不同时期加用胰岛素治疗妊娠合并糖尿病孕产妇对血糖控制的效果及妊娠结局的影响。方法：选取本院接受治疗的妊娠合并糖尿病孕妇90例，随机分为对照组、观察组，各45例。对照组患者于32周后应用胰岛素配合饮食治疗，观察组患者于32周前实行，观察两组患者的血糖情况以及妊娠结局。结果：观察组患者的产后并发症发生率低于对照组，各项数据有统计学意义（P<0.05）。结论：在妊娠早期对患有糖尿病的孕妇使用胰岛素治疗，能有效降低孕妇的各种并发症，还能降低新生儿各种病症的发生率，治疗效果比在妊娠后期使用药物治疗效果更好，最好是在32周之前应用治疗。

【关键词】胰岛素;妊娠合并糖尿病孕妇;血糖控制

Effects of insulin therapy on blood glucose control and pregnancy outcome in pregnant women with diabetes mellitus

Dong Huiqin

Shandong Liaocheng Dongchangfu District Hospital of Traditional Chinese Medicine， Liaocheng， Shandong 252000

[Abstract] Objective：To explore the effect of insulin on blood glucose control and pregnancy outcome of pregnant women with gestational diabetes combined with pregnancy in different stages. Methods： A total of 90 pregnant women with gestational diabetes who received treatment in our hospital were selected. Patients in the control group were treated with insulin and diet after 32 weeks， and patients in the observation group were treated before 32 to observe their blood glucose and pregnancy outcome. Results： The incidence of postpartum complications in the observation group was lower than that in the control group（P<0.05）. Conclusion： Insulin treatment in pregnant women with diabetes in early pregnancy can effectively reduce the complications of pregnant women， and also reduce the incidence of various diseases in neonates. The treatment effect is better than that of drug treatment in late pregnancy. It is better to use the treatment before 32 weeks.

[Key words]Insulin; Pregnancy with diabetes; Blood glucose control

妊娠合并糖尿病孕妇的生产风险高于一般孕妇，它是指在妊娠期正常的情况下出现糖代谢紊乱，致病原因有许多种，如遗传、高龄产妇、肥胖、胰岛素抵抗等等，临床表现一般为羊水积累过多、阴部出现肿大瘙痒。孕妇分娩前的血糖控制十分重要，直接影響新生儿的健康。有研究报告指出，在孕妇生产前对其实行胰岛素配合饮食、运动治疗的方法能大大降低孕妇的分娩风险[1-2]。本报告探究不同时期加用胰岛素治疗妊娠合并糖尿病孕产妇的对血糖控制效果及妊娠结局的影响，报告如下。

1 资料与方法

1.1 一般资料

选择在2017年10月至2018年7月在本院接受治疗的90例妊娠合并糖尿病孕妇，随机分为对照组以及观察组，各45例。对照组孕妇年龄为23～40岁，平均年龄为（26.2±0.23）岁;观察组孕妇年龄为24～38岁，平均年龄为（28.6±0.08）岁。本报告所研究的患者均出现体内糖代谢病理性紊乱，被确诊为妊娠期糖尿病，患者均无其他重要代谢类疾病以及重要器官功能代谢性障碍，符合本次研究的标准。……