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血清CRP在小儿支原体肺炎诊治中的价值

2019-10-21陈艳丽

医学信息 2019年18期

陈艳丽

摘要:目的  探讨血清CRP在小儿支原体肺炎诊治中的应用价值。方法  选择2017年1月~2018年12月我院收治的200例肺炎患儿作为观察组,根据疾病严重程度进一步分为轻症组和重症组,各100例,同期纳入健康体检儿童100例作为对照组,比较三组血清CRP水平,分析血清CRP与疾病严重程度的关系。结果  观察组血清CRP为(22.96±1.86)mg/L,高于对照组的(2.19±0.42)mg/L,差异有统计学意义(P<0.05);治疗后,轻症组与重症组血清CRP均低于治疗前,差异有统计学意义(P<0.05);重症组血清CRP水平为(9.03±1.12)mg/L,高于轻症组的(5.02±0.47)mg/L,但差异无统计学意义(P>0.05)。结论  支原体肺炎患儿在接受治疗过程中进行检测血清CRP对评估病情严重程度有一定的意义,可用于指导临床制定治疗措施。

关键词:血清CRP;小儿支原体肺炎;呼吸道感染

中图分类号:R197.1                                    文献标识码:A                              DOI:10.3969/j.issn.1006-1959.2019.18.064

文章编号:1006-1959(2019)18-0181-02

Abstract:Objective  To investigate the value of serum CRP in the diagnosis and treatment of mycoplasmal pneumonia in children. Methods  From January 2017 to December 2018, 200 children with pneumonia admitted to our hospital were selected as observation group. According to the severity of the disease, they were further divided into mild group and severe group, 100 cases in each group. In the same period, 100 children in our hospital were included as a control group, and the serum CRP levels of the three groups were compared. Results  The serum CRP of the observation group was (22.96±1.86) mg/L, which was higher than that of the control group (2.19±0.42) mg/L, the difference was statistically significant (P<0.05). After treatment, the serum CRP of the mild group and the severe group were observed,the difference was statistically significant (P<0.05). The serum CRP level in the severe group was (9.03±1.12) mg/L, which was higher than that in the mild group (5.02±0.47) mg/L,the difference was no statistically significant (P>0.05). Conclusion  The detection of serum CRP in children with mycoplasmal pneumonia has a certain significance in assessing the severity of the disease and can be used to guide the clinical development of treatment measures.

Key words:Serum CRP;Pediatric mycoplasmal pneumonia;Respiratory infection

支原体是一种介于细菌与病毒之间的病原微生物,主要通过呼吸道飞沫传播,是学龄儿童呼吸道感染的主要病原体之一。对于感染支原体而导致支原体肺炎的患儿,支原体首先侵犯呼吸道上皮细胞,导致呼吸道黏膜受损,腺体分泌增加,气道反应性增高[1]。因此,支原体肺炎患儿会出现刺激性咳嗽,同时伴有发热等临床症状,部分患儿咳嗽会转变顽固性剧咳[2]。研究指出,支原体肺炎的发生会导致血清CRP的异常改变[3]。在对患儿开展临床治疗之前,对血清CRP进行檢测能够评估病情严重程度,有利于治疗方案的确定。为验证其作用,本研究选择不同严重程度的支原体肺炎患儿200例,检测其血清CRP水平,分析其与患儿病情严重程度的关系,现报道如下。

1资料与方法

1.1一般资料  选择天津市武清区人民医院2017年1月~2018年12月收治的200例支原体肺炎患儿作为研究对象,本研究经我院伦理委员会审批通过,患儿家属对本次研究知情同意并签署知情同意书。……

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