柯伟良 李上海 李日健 黄春燕

【摘要】 目的：探究經皮冠脉介入术（percutaneous coronary intervention，PCI）治疗高龄冠心病心绞痛的临床效果。方法：选取2017年2月-2018年2月高龄冠心病心绞痛患者100例，随机分为对照组（常规治疗）与观察组（对照组基础上给予PCI），各50例，对比两组临床疗效、SAQ评分、生活质量（GQOL-74）及1年内心血管事件发生率。结果：观察组治疗总有效率为98.00%，高于对照组的80.00%（P<0.05）。治疗30 d后，观察组患者的SAQ各项评分均优于对照组（P<0.05）。治疗前，两组患者的GQOL-74评分比较差异无统计学意义（P>0.05）;治疗1年后，观察组患者的GQOL-74各项评分均优于对照组（P<0.05）。观察组患者1年内心血管不良事件发生率为10.00%，低于对照组的44.00%（P<0.05）。结论：高龄冠心病心绞痛患者接受PCI治疗的效果显著，对改善生活质量作用明显，有助于预防心血管事件，值得大力推广。

【关键词】 冠心病 心绞痛 PCI 临床疗效

doi：10.14033/j.cnki.cfmr.2019.28.063 文献标识码 B 文章编号 1674-6805（2019）28-0-03

Clinical Analysis of Coronary Intervention for Angina Pectoris in Elderly Patients with Coronary Heart Disease/KE Weiliang， LI Shanghai， LI Rijian， HUANG Chunyan. //Chinese and Foreign Medical Research， 2019， 17（28）： -151

[Abstract] Objective： To explore the clinical efficacy of PCI in the treatment of angina pectoris in elderly patients with coronary heart disease. Method： From February 2017 to February 2018， 100 elderly angina pectoris patients with coronary heart disease were selected and randomly divided into the control group （conventional treatment） and the observation group （given PCI on the basis of the control group）， 50 patients in each group. The clinical efficacy， SAQ score， quality of life （GQOL-74） and the incidence of cardiovascular events within 1 year were compared between the two groups. Result： The total effective rate was 98.00% in the observation group， which was significantly higher than 80.00% in the control group （P<0.05）. After 1 month of treatment， SAQ scores in the observation group were all better than those in the control group （P<0.05）. Before treatment， there were no significant differences of the GQOL-74 scores between the two groups （P>0.05）. After 1 year of treatment， the GQOL-74 scores in the observation group were all significantly better than those in the control group （P<0.05）. The incidence of cardiovascular adverse events within 1 year was 10.00% in the observation group， which was significantly lower than 44.00% in the control group （P<0.05）. Conclusion： PCI treatment for elderly angina pectoris patients with coronary heart disease has a significant effect on improving the quality of life and preventing cardiovascular events， which is worthy of promotion.

[Key words] Coronary heart disease Angina pectoris PCI Clinical curative effect

First-authors address： Affiliated Hospital of Guangdong Medical University， Zhanjiang 524001， China

冠心病是当前较为常见的心脏疾病，患者常见有不稳定性心绞痛，近年来受到生活方式变化及人口老龄化加剧的影响，冠心病心绞痛的发病率不断上升，对患者生活质量造成严重影响的同时，也威胁到了患者的生命安全[1]。经皮冠脉介入术（percutaneous coronary intervention，PCI）是冠心病心绞痛的常用治疗方式之一，其治疗效果受到广泛认可[2]。本次研究主要探讨PCI运用于高龄冠心病心绞痛患者临床治疗的效果，现报道如下。

1 资料与方法

1.1 一般资料

选取2017年2月-2018年2月笔者所在科收治的高龄冠心病心绞痛患者100例，纳入标准：患者年龄≥65岁;经冠状动脉造影确诊为冠心病，符合冠心病心绞痛的诊断标准[3];临床资料完整。排除标准：意识不清;使用了对研究结果造成影响的药物;恶性肿瘤;心肌梗死;药物禁忌。患者知情同意入组，经笔者所在医院伦理委员批准。采用随机数字表将其分为观察组与对照组，各50例。观察组患者中，男28例，女22例;年龄65～79岁，平均（69.54±2.42）岁。对照组患者中，男27例，女23例;年龄65～78岁，平均（68.68±2.44）岁。……