肖俊杰 杨文娟 梁丽丽 万信 冯秀君 林雪娟

摘要 目的：研究慢性胃炎濕热证病性湿、热与病位证素的相关性，为临床诊疗提供参考依据。方法：采用证素辨证的方法筛选出312例慢性胃炎湿热证患者，探讨湿热证病性湿、热与病位证素之间的关系。结果：312例慢性胃炎湿热证患者的常见的病位证素出现的频数从高往低的分布情况为：胃>脾>肝>肾>肺=胆;湿与脏腑病位证素的相关系数从高到低依次为：脾>胃>肝>肾>胆>肺。结果表明湿与脾、胃、肝存在显著的相关性（P<0.001），与肾、胆、肺不存在相关性（P>0.005）。热与脏腑病位证素的相关系数从高到低依次为：肝>胆>胃>脾>肺>肾。结果表明热与肝、胆、胃、脾存在相关性（P<0.005），与肺、肾不存在相关性（P>0.005）。结论：湿热证是慢性胃炎的重要证型，病性证素湿与热均与胃、脾、肝相关。

关键词 慢性胃炎;湿热证;病性;病位;相关性

Correlation between Pattern Elements of Disease Nature and Disease Location

in Damp Heat Pattern of Chronic Gastritis

Xiao Junjie1，Yang Wenjuan1，Liang Lili1，Wan Xin1，Feng Xiujun1，Lin Xuejuan2

（1 TCM Pattern Research Base of Fujian University of Traditional Chinese Medicine，Fuzhou 350122，China;

2 Health Status Identification of Traditional Chinese Medicine in Fujian Province Key Laboratory

（Fujian University of Traditional Chinese Medicine），Fuzhou 350122，China）

Abstract Objective：To investigate the correlation between dampness，heat of pattern elements of disease nature and pattern elements of disease location in damp-heat pattern of chronic gastritis，and to provide reference for clinical diagnosis and treatment.Methods：A total of 312 cases of chronic gastritis with damp-heat pattern were selected by the method of pattern differentiation，and the relationship between dampness，heat of pattern elements of disease nature and pattern elements of disease location in damp-heat pattern was discussed.Results：The distributed feature of the frequency of pattern elements of disease location in 312 cases of chronic gastritis with damp-heat pattern in descending order was：stomach>spleen>liver>kidney>lung>gallbladder; the distributed feature of the correlation coefficient between dampness and pattern elements of disease location in internal organs in descending order was：spleen>stomach>liver>kidney>gallbladder>lung.The results showed that there was a significant correlation between dampness and spleen，stomach and liver （P<0.001），and there was no correlation between the kidney，gallbladder and lung （P>0.005）.The distributed feature of the correlation coefficient between of heat and pattern elements of disease location in internal organs in descending order was：liver>gallbladder>stomach>spleen>lung>kidney.The results showed that there was a correlation between heat and liver，gallbladder，stomach and spleen （P<0.005），and there was no correlation between lung and kidney （P<0.005）.Conclusion：Damp-heat pattern is an important pattern type of chronic gastritis，and the dampness and heat of pattern elements of disease nature are related to the stomach，spleen and liver.

Key Words Chronic gastritis; Damp heat pattern; Disease nature; Disease location; Relationship

中图分类号：R256.3文献标识码：Adoi：10.3969/j.issn.1673-7202.2018.03.052

慢性胃炎（Chronic Gastritis，CG）作为一种十分常见且多发的消化系统疾病，患者临床常见症状为上腹部饱胀感、疼痛或嗳气等。它是由不同病因引起的胃黏膜慢性炎性反应或萎缩性病变，约占接受胃镜检查患者的80%～90%[1]。根据2011年中国中西医结合学会消化系疾病专业委员会制订的慢性胃炎中西医结合诊疗共识意见，将其分为肝郁气滞、肝胃郁热、脾胃湿热、胃络瘀阻、脾胃虚寒、胃阴不足六型[2]。本课题组前期大量文献调研也表明，湿与热是慢性胃炎常见的病性证素，且为两病性组合证素频次最高[3]。本文主要通过证素辨证的方法，分析慢性胃炎湿热证病性湿、热与病位的相关性，分析湿、热证素在慢性胃炎病变过程中的作为，为临床的诊疗提供参考。