杨芬

[摘要] 目的 比较妥布霉素地塞米松滴眼液和氟米龙滴眼液对急性前葡萄膜炎的治疗效果，为急性前葡萄膜炎的治疗选取有效药物。方法 方便选取该院2014年7月—2016年9月收治的急性前葡萄膜炎患者80例，以随机数字表法分为两组各40例，观察组以妥布霉素地塞米松眼液治疗，对照组采用氟米龙眼液治疗，比较两组患者治疗效果、治愈时间及疾病复发情况。结果 观察组治疗总有效率92.50%明显高于对照组的75.00%（χ2=4.501，P=0.034），治愈时间（13.16±2.01）d明显短于对照组的（18.35±2.14）d（t=7.045，P=0.000），且6个月、12个月时观察组复发率0.00%、2.50%明显低于对照组的12.50%、20.00%（χ2=5.333、4.507，P=0.021、0.034）。结论 与氟米龙滴眼液相比，妥布霉素地塞米松滴眼液对急性前葡萄膜炎的疗效更为显著，患者治愈更快，疾病复发风险更低，值得推广。

[关键词] 妥布霉素地塞米松滴眼液；前葡萄膜炎；氟米龙滴眼液

[中图分类号] R776 [文献标识码] A [文章编号] 1674-0742（2018）03（c）-0116-03

Comparison of Curative Effect of Tobramycin and Dexamethasone Eye Drops and Fluorometholone Eye Drops in Treatment of Acute Anterior Uveitis

YANG Fen

Department of Otolaryngology， Kunming Hospital of TCM， Kunming， Yunnan Province， 650000 China

[Abstract] Objective To compare the effect of tobramycin and dexamethasone eye drops and fluorometholone eye drops in treatment of acute anterior uveitis thus providing reference for the treatment of acute anterior uveitis. Methods 80 cases of patients with acute anterior uveitis admitted and treated in our hospital from July 2014 to September 2016 were conveniently selected and randomly divided into two groups with 40 cases in each， the observation group and the control group were respectively treated with tobramycin and dexamethasone eye drops and fluorometholone eye drops， and the treatment effect， healing time and disease recurrence were compared between the two groups. Results The total effective rate in the observation group was obviously higher than that in the control group， （92.50% vs 75.00%）（χ2=4.501，P=0.034）， and the healing time was obviously shorter than that in the control group[（13.16±2.01）d vs （18.35±2.14）d]，（t=7.045，P=0.000）， and the recurrence rates in 6 months and 12 months in the observation group were obviously lower than those in the control group（0.00%，2.50% vs 12.50%，20.00%），（χ2=5.333，4.507，P=0.021，0.034）. Conclusion The curative effect of tobramycin and dexamethasone eye drops in treatment of acute anterior uveitis is more obvious， which can promote the healing of patients with lower recurrence risk of diseases， and it is worth promotion.

[Key words] Tobramycin and dexamethasone eye drops； Anterior uveitis； Fluorometholone eye drops

在臨床眼科中，急性前葡萄膜炎是一种特别常见的葡萄膜病，病症常先发于单眼[1]，葡萄膜炎在临床上的表现主要为羞明、眼痛以及视力方面的减退[2]。统计[3]显示，在全球范围内，葡萄膜炎所致盲目在所有盲目患者中，占比为4%～10%，且其发生率呈现逐渐升高趋势，因此对该病应积极治疗。目前急性前葡萄膜炎可用治疗药物较多，该研究方便选取该院2014年7月—2016年9月收治的急性前葡萄膜炎患者80例，随机将临床患者分为两组，分别使用氟米龙滴眼液和妥布霉素地塞米松滴眼液各自进行治疗。治疗过程中，跟踪临床疗效，结果发现应用妥布霉素地塞米松滴眼液治疗的患者疗效更加，疾病复发风险也更低，现报道如下。……