APP下载

肝脏疾病诊断中采取血清ALT、AST、GGT检测的临床应用

2018-08-31黎明高

中外医学研究 2018年11期
关键词:临床应用诊断

黎明高

【摘要】 目的:对肝脏疾病诊断中采取血清ALT(丙氨酸氨基转移酶)、AST(天门冬氨酸氨基转移酶)、GGT(谷氨酰基转移酶)检测的临床应用进行研究分析。方法:选取笔者所在医院接诊的肝脏疾病病患130例为试验组,另选择80例在笔者所在医院行健康体检的健康人员为对照组。使用全自动分化仪检测两组人员的血清ALT、AST、GGT水平和阳性体现状况,分析对照组与各类型肝脏疾病病患血清ALT、AST、GGT水平变化和阳性体现状况。结果:试验组病患的血清ALT、AST、GGT水平明顯高于对照组,差异有统计学意义(P<0.05);并且试验组病患不同类型肝脏疾病间的血清水平比较差异有统计学意义(P<0.05);在阳性体现状况中试验组病患ALT阳性率分别为慢性病毒性肝炎94.83%、肝硬化39.13%、肝癌26.92%;AST阳性率分别为慢性病毒性肝炎89.66%、肝硬化86.96%、肝癌84.62%;GGT阳性率分别为肝癌76.92%、56.9%、肝硬化63.04%、慢性病毒性肝炎56.9%。结论:在肝脏疾病诊断中血清ALT、AST、GGT水平检测有着重要的作用,其为肝脏疾病诊断提供了更为科学的辨别依据,有着较高的临床推广应用价值。

【关键词】 肝脏疾病; ALT; AST; GGT; 诊断; 临床应用

doi:10.14033/j.cnki.cfmr.2018.11.088 文献标识码 B 文章编号 1674-6805(2018)11-0179-03

Clinical Application of Serum ALT,AST,GGT Detection in Liver Disease Diagnosis/LI Minggao.//Chinese and Foreign Medical Research,2018,16(11):179-181

【Abstract】 Objective:To analyze of the serum ALT (alanine aminotransferase),AST (aspartate aminotransferase),GGT (glutamyl transferase) in the diagnosis of liver disease.Method:130 patients with liver diseases in our hospital were selected as the experimental group,and 80 healthy persons who underwent physical examination in our hospital as the control group.The serum levels of ALT,AST,GGT and positive expression of two groups of patients were detected by automatic differentiation instrument,and the changes of serum ALT,AST,GGT levels and positive expression status were analyzed in control group and various types of liver diseases.Result:The experimental group patients serum ALT,AST and GGT levels were significantly higher than the control group,the differences were significant(P<0.05),and the experimental group had serum level of comparison between different types of liver disease also had statistical significance(P<0.05),in the experimental group positive rate reflects the status of patients with ALT respectively were chronic viral hepatitis,liver cirrhosis,liver cancer,they were 94.83%,39.13%,26.92% respectively,the positive rate of AST of chronic viral hepatitis,liver cirrhosis,liver cancer were 89.66%,86.96%,84.62%,the positive rate of GGT of chronic viral hepatitis,liver cirrhosis,liver cancer were 56.9%,63.04%,76.92%.Conclusion:The detection of serum ALT,AST and GGT levels play an important role in the diagnosis of liver diseases,which provides a more scientific basis for the diagnosis of liver diseases,and has high clinical application value.

【Key words】 Liver disease; Alanine Aminotransferase; Aspartate aminotransferase; Glutamyl transferase; Diagnostic; Clinical application

First-authors address:Chinese Medicine Hospital of Jingshan,Jingshan 431899,China

在临床中较为常见的疾病之一包括病毒性肝炎,其是因多种肝炎病毒而引发的一类传染病,有着较高的病发率,通常多以肝脏受损为主,当中丙型肝炎与乙型肝炎最容易演变为慢性病毒性肝炎或进一步向肝硬化发展。因为肝硬化多为慢性发展,病患通常都无较为明显的症状,直到代偿期才体现出门脉高压和肝受损厉害的症状,此时少量的病患会发展成肝癌。而肝癌是国内多见的恶性肿瘤之一,其发病率与病亡率都非常高,由于初期病患症状不明显,多数在就医时已到中晚期,丧失了最佳的手术治疗机会,从而提高了病亡率。故在此类疾病的诊断中有效的诊断方法与标准已成为医学界重点关注。此次笔者所在医院对血清ALT、AST、GGT水平变化在肝脏疾病诊断中的应用进行了研究分析,现将结果报道如下。

1 资料……

登录APP查看全文

猜你喜欢

临床应用诊断
中医护理在糖尿病足患者足部护理的临床应用修改
超声引导下乳腺穿刺活检的临床应用探讨
奥美拉唑的药学药理分析及临床应用探讨
常见羽毛球运动软组织损伤及诊断分析
浅析涌泉穴
浅谈猪喘气病的病因、诊断及防治
珍珠的市场前景及药性成分、功效的研究
信息技术与传统技术在当代汽车维修中的应用分析
红外线测温仪在汽车诊断中的应用
窄带成像联合放大内镜在胃黏膜早期病变诊断中的应用