头孢曲松联合阿奇霉素治疗老年糖尿病合并肺炎效果研究
2018-08-23张军
张军
[摘要] 目的 探讨头孢曲松联合阿奇霉素治疗老年糖尿病合并肺炎的效果。方法 选取该院2016年1月—2017年11月收治的老年糖尿病合并肺炎患者178例,随机分为两组各89例,对照组给予头孢曲松治疗,观察组在对照组的基础上给予阿奇霉素治疗,比较效果。结果 观察组总有效率为94.4%,明显优于对照组83.1%(P<0.05);观察组症状消失时间、空腹血糖、住院时间明显少于对照组(P<0.05)。结论 对老年糖尿病合并肺炎患者采用头孢曲松联合阿奇霉素治疗,能有效提高治疗效果,缓解临床症状,促进患者康复,值得应用。
[关键词] 头孢曲松;阿奇霉素;老年糖尿病;肺炎
[中图分类号] R587.1 [文献标识码] A [文章编号] 1672-4062(2018)02(b)-0080-02
Effect of Ceftriaxone and Azithromycin on Elderly Diabetic Patients with Pneumonia
ZHANG Jun
Pharmacy Department, Changchun Central Hospital, Changchun, Jilin Province, 130000 China
[Abstract] Objective This paper tries to investigate the efficacy of ceftriaxone combined with azithromycin in the treatment of diabetes mellitus complicated with pneumonia. Methods 178 elderly patients with diabetes mellitus complicated with pneumonia admitted to this hospital from January 2016 to November 2017 were randomly divided into two groups of 89 patients in each group. The control group received ceftriaxone treatment. The observation group received azithromycin treatment on the basis of the control group. The curative effects of the two groups were compared. Results The total effective rate was 94.4% in the observation group, which was significantly better than that in the control group(83.1%)(P<0.05). The time of disappearance of symptoms, fasting blood glucose, and hospital stay were significantly less in the observation group than in the control group(P<0.05). Conclusion The use of ceftriaxone combined with azithromycin in elderly patients with diabetes mellitus complicated with pneumonia can effectively improve the therapeutic effect, relieve clinical symptoms, and promote the recovery of patients. It is worth applying.
[Key words] Ceftriaxone; Azithromycin; Senile diabetes; Pneumonia
糖尿病與肺炎都是临床常见病、多发病。近年来,因各种不良因素的影响,糖尿病与肺炎的发生率都不断呈增高趋势。对老年人来说,由于其身体各器官处于衰退状态,身体防御能力及免疫功能下降,再加上长期高血糖导致患者体内代谢功能紊乱,可引起各部位感染的发生,尤其容易诱发呼吸道疾病,报道表明[1],在老年人多器官功能衰竭的发病诱因中,肺部感染占75.4%~82.8%。老年糖尿病合并肺炎发生时病情常难以控制,且抗生素治疗效果也往往不佳。因此,应用合理的抗生素治疗老年糖尿病合并肺炎,对提高治疗效果,改善患者预后有重要意义,也是临床研究的重点[2]。该文对该院2016年1月—2017年11月收治的89例糖尿病合并肺炎的老年患者,采用头孢曲松联合阿奇霉素治疗,探讨其治疗效果,现报道如下。
1 资料与方法
1.1 一般资料
选取该院收治的糖尿病合并肺炎的老年患者178例为观察对象,均符合2010年美国糖尿病协会糖尿病诊断标准[3]及《社区获得性肺炎诊断标准》(中华医学会呼吸病学分会2006年制定)[4]。……
