杨晓琴

[摘要] 目的 探讨在宫颈癌前期病变宫颈上皮内瘤变的治疗上LEEP锥切术的应用价值。 方法 回顾性分析于2016年7月～2017年10月在我院接受诊疗的70例宫颈癌前期病变宫颈上皮内瘤变患者的临床资料，并依据数字表法将其随机分成两组（对照组与实验组），每组35例。对照组和实验组分别利用冷刀锥切术和LEEP锥切术给予治疗，对两组患者的手术成果进行对比。 结果 对照组的总痊愈率（77.19%）显著低于实验组（总痊愈率为94.28%）（P<0.05）；对照组的宫颈恢复时间、手术时间均明显长于实验组，术中出血量明显多于实验组，差异有统计学的意义（P<0.05）。 结论 在宫颈癌前期病变宫颈上皮内瘤变的治疗上，LEEP锥切术能够对患者的手术时间进行显著缩短，加快患者宫颈的恢复，其具有优异的治愈效果。

[关键词] 宫颈癌前期病变；宫颈上皮内瘤变；LEEP锥切术；治疗观察

[中图分类号] R737.3 [文献标识码] B [文章编号] 1673-9701（2018）10-0057-03

Observation on LEEP conization in the treatment of cervical intraepithelial neoplasias of precursor lesions of cervical cancer

YANG Xiaoqin

Department of Gynecology and Obstetrics， Macheng Women and Children's Hospital in Hubei Province， Macheng 438300， China

[Abstract] Objective To investigate the application value of LEEP conization in the treatment of cervical intraepithelial neoplasia of precursor lesions of cervical cancer. Methods The clinical data of 70 cases of cervical intraepithelial neoplasia of precursor lesions of cervical cancer who were treated in our hospital from July 2016 to October 2017 were retrospectively analyzed. According to digital table method， the patients were randomLy divided into two groups （control group and experimental group）， with 35 cases in each group. The control group and the experimental group were treated with cold knife conization and LEEP conization respectively. The surgical outcomes of two groups of patients were compared and discussed. Results The total cure rate in the control group（77.19%） was significantly lower than that in the experimental group total cure rate of 94.28%（P<0.05）； the cervical recovery time and operation time in the control group were significantly longer than those in the experimental group. The volume of intraoperative bleeding was significantly more than that in the experimental group（P<0.05）. The difference was statistically significant. Conclusion In the treatment of cervical intraepithelial neoplasia of precursor lesions of cervical cancer， LEEP conization can significantly shorten the operation time of patients and accelerate the recovery of cervix， which has an excellent healing effect.

[Key words] Precursor lesions of cervical cancer； Cervical intraepithelial neoplasia； LEEP conization； Treatment and observation

宮颈上皮内瘤变（cervical intraepithelial neoplasia，CIN）是一种宫颈癌的癌前病变，其与宫颈浸润癌具有密切关系，该疾病包含有宫颈原位癌和宫颈不典型增生，常见病因为外源性与内源性免疫缺陷、微生物感染、吸烟和人类乳头状瘤病毒等。宫颈上皮内瘤变以息肉、糜烂、充血、宫颈肥大、接触性出血、白带带血和白带增多等慢性宫颈炎为常见的临床症状，其会对女性身体造成极大的伤害[1-2]。我院为探寻在宫颈上皮内瘤变治疗上具有优异疗效的手术方案，现对35例宫颈癌前期病变宫颈上皮内瘤变患者采用LEEP锥切术，并分析手术疗效，现报道如下。

1 资料与方法

1.1 一般资料

搜集分析我院收治的70例宫颈癌前期病变宫颈上皮内瘤变患者的临床资料，患者就诊时间2016年7月～2017年10月之间。所有宫颈癌前期病变宫颈上皮内瘤变患者均经组织病理学或阴道镜下宫颈检查诊断，合乎第8版《妇产科学》中有关CIN的诊断标准[3]，且已自愿签署知情同意书。……