急性心肌梗死基层溶栓治疗的探讨
2018-06-08董冠忠
董冠忠
[摘要] 目的 分析和研究急性心肌梗死基层溶栓治療的临床疗效。方法 方便选取该院在2015年5月—2017年5月期间收治的95例急性心肌梗死患者作为研究对象,所有患者均采用溶栓治疗,对其临床资料进行回顾性分析,观察患者的病死率和不良反应发生率,同时还需要比较不同发病溶栓时间以及不同年龄阶段中患者的再通率。结果 在95例患者中,共有53例患者冠状动脉再通,其再通率为50.35%;共有6例患者发生死亡,其病死率为6.32%;共有17例患者发生不良反应,其不良反应发生率为17.89%。发病至溶栓时间<6 h患者的再通率(71.67%)要显著高于6~12 h(37.04%)以及>12 h的患者再通率(0.00%),比较差异有统计学意义(χ2=5.074 3,P<0.05)。 结论 在基层医院中采用溶栓治疗急性心肌梗死,患者的临床症状能够得到有效改善,但溶栓时间越早,患者冠状动脉再通率越高,因此需要争取尽早溶栓,值得推广。
[关键词] 急性心肌梗死;基层溶栓治疗;再通率;病死率;不良反应
[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742(2018)02(a)-0036-03
Study on Thrombolytic Therapy for Acute Myocardial Infarction
DONG Guan-zhong
Department of Cardiology, Dongming County Peoples Hospital, Heze, Shandong Province, 274500 China
[Abstract] Objective This paper tries to analyze and study the clinical curative effect of acute myocardial infarction. Methods 95 cases of patients with acute myocardial infarction from May 2015 to May 2017 treated in this hospital were convenient selected as the research objects, all patients were treated with thrombolysis, the clinical data were retrospectively analyzed, and the mortality and incidence of adverse reactions were observed, at the same time, different onset thrombolysis time and the rate of patients in different age stages were compared. Results In all 95 patients, 53 patients had coronary artery repass, and the regeneration rate was 50.35%. A total of 6 patients died, with a fatality rate of 6.32%. A total of 17 patients had adverse reactions and the incidence of adverse reactions was 17.89%. The regeneration rate of patients with onset of thrombolytic time <6 h(71.67%) was significantly higher than that of patients with 6~12 h (37.04%) and > 12 h(0.00%), and the difference was statistically significant(χ2=5.074 3, P<0.05). Conclusion In the basic-level hospitals using thrombolysis treatment of acute myocardial infarction, the patients clinical symptoms can be effectively improved, but the earlier thrombolysis time, patients with coronary artery, the higher the rate of so need to strive for the early thrombolysis, which is worthy of promotion.
[Key words] Acute myocardial infarction; Treatment of primary thrombolysis; Regeneration rate; Fatality rate; Adverse reaction
作为基层医院中一种常见的疾病种类,急性心肌梗死发病急,如果没有及时得到有效治疗,患者病死率比较高,主要是由于斑块破裂,导致局部形成血栓,造成血管急性闭塞,因此在临床治疗中需要快速恢复血流。目前在临床治疗中主要是采用急诊介入治疗,其效果较为显著,但是对于一些基层医院来说,由于不具备介入治疗的条件,所以在临床治疗中溶栓治疗就成为首选。而且在近几年,随着在临床中开始使用新型溶栓药物,在很大程度上提高了冠状动脉的再通率,而且患者开始溶栓的时间与其再通率的高低之间存在直接的相关性,一般开始溶栓时间越早,患者再通率就越高,其预后效果也就越好。该文主要是针对该院在2015年5月—2017年5月期间收治的95例急性心肌梗死患者采取溶栓治疗,对其临床资料进行回顾性分析,现报道如下。……
