不同剂量盐酸氨溴索辅助治疗老年肺炎的疗效观察
2018-06-04陈昌明
陈昌明
【摘 要】目的:探究老年肺炎治疗中使用不同剂量盐酸氨溴索辅助治疗的效果。方法:随机选取80例老年肺炎患者,分成两组,观察组40例采用大剂量盐酸氨溴索辅助治疗,对照组40例采用小剂量盐酸氨溴索辅助治疗。结果:治疗后,两组患者之间的痰量、气喘、肺啰音、咳嗽等消失时间相比统计学差异较为显著,P<0.05;且观察组患者治疗后血CRP、痰TNF-α、痰IL-8等炎症因子水平同对照组患者相比具有明显优势,P<0.05;另外,观察组和对照组患者治疗总有效分别为90.0%、75.0%,相比差异较为明显,P<0.05。结论:老年肺炎采用大剂量盐酸氨溴索进行辅助治疗,得到的临床治疗效果较为显著,临床上可以结合患者具体情况适当增加盐酸氨溴索辅助治疗。
【关键词】不同剂量;盐酸氨溴索;老年肺炎;治疗效果
Abstract Objective: To explore the effect of ambroxol with different doses of ambroxol in the treatment of senile pneumonia. Methods: 80 elderly patients with pneumonia were randomly divided into two groups, 40 cases in the observation group were treated with ambroxol hydrochloride, and 40 cases in the control group were treated with ambroxol hydrochloride. Results: after the treatment, the sputum volume, between the two groups of patients with asthma, pulmonary rales, cough disappeared time difference is significant difference, P< 0.05; and the patients in the observation group after treatment, the levels of inflammatory factors of blood CRP, TNF-α, IL-8, alpha phlegm phlegm patients compared with the control group has obvious advantages, P< 0.05; in addition, the observation group and the control group of patients with total effective treatment were 90% and 75%, the difference is obvious, P< 0.05. Conclusion: the elderly pneumonia with large dose ambroxol hydrochloride adjuvant therapy, the clinical effect is more significant, clinical can be combined with the specific circumstances of patients, increase the ambroxol hydrochloride adjuvant therapy.
Key words: Different doses; ambroxol hydrochloride; senile pneumonia; therapeutic effect
【中圖分类号】 R749.053【文献标识码】 B 【文章编号】 1672-3783(2018)04-03-040-01
前言
临床上,肺炎是老年人十分常见的疾病之一,老年人由于机体各项功能降低,咳痰无力,很容易造成痰液粘稠,不易咳出,从而对患者的恢复带来极大影响,严重的阻塞患者呼吸道,进而使得患者生命安全得到威胁[1]。所以在治疗老年肺炎时,要特别注重祛痰[2]。盐酸氨溴索是一种比较常见的祛痰药物,可以促进患者气道平滑肌松弛,保持患者呼吸通道顺畅,由于临床上并没有针对盐酸氨溴索的用量进行统一规定,对此,本文就不同剂量盐酸氨溴索治疗老年肺炎的效果进行分析,报道如下。
1 资料与方法
1.1 临床资料 从我科室2016年4月至2017年9月收治的老年肺炎患者中,随机选取80例进行资料统计分析,本次研究选取全部对象在入组前均获得知情权,并签署自愿同意书。随机将其分为两组,分别为观察组和对照组,其临床基本资料相对比统计学差异不显著,P>0.05,可对比。
1.2 方法 患者入院后,均采取常规措施进行处理,包括吸氧和抗感染等。之后根据患者具体临床症状、过往病史及用药禁忌史等选取相应的抗生素进行治疗。……
