修德涛

[摘要] 目的 分析和研究中西医结合治疗早期糖尿病肾病的临床应用效果。方法 方便选取该院在2016年5月—2017年5月期间该院收治的78例早期糖尿病肾病患者作为研究对象，按照入院单号单双数将患者划分为参照组和研究组，各39例，其中参照组患者采用常规西医治疗，研究组患者采用中西医结合治疗，观察和比较两组患者的临床疗效。结果 参照组患者的治疗总有效率为74.36%，研究组患者的治疗总有效率为94.87%，治疗后参照组患者的纤维蛋白原、血浆粘度分别为（4.56±0.58）g/L、（1.26±0.35）mPsa、研究组患者的纤维蛋白原、血浆粘度分别为（3.25±0.62）g/L、（1.43±0.21）mPsa，由此可以看出，研究组患者的治疗有效率要显著高于参照组（χ2=6.317 2），且研究组患者血液流变学和尿微量白蛋白相关指标的改善效果更加显著，差异有统计学意义（P<0.05）。 结论 采用中西医结合治疗早期糖尿病肾病，能够显著提高患者的临床治疗效果，同时在血液黏稠度降低、脂质代谢调节、蛋白质减少等方面也具有良好的效果，值得推广。

[关键词] 早期糖尿病肾病；中西醫结合治疗；血液流变学；尿微量白蛋白

[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742（2018）01（a）-0169-03

Clinical Study on Treatment of Early Diabetic Nephropathy by Integrative Chinese and Western Medicine

XIU De-tao

Department of Inner Medicine， Section Two， Yucheng Traditional Chinese Medicine Hospital， Yucheng， Shandong Province， 251200 China

[Abstract] Objective This paper tries to analyze and study the clinical effect of traditional Chinese and western medicine on early diabetic nephropathy. Methods 78 cases of early diabetic nephropathy patients from May 2016 to May 2017 were convenient selected as the research objects， according to the hospital order number and odd number will be divided into control group and research group， with 39 cases in each group， the control group was treated by routine western medicine treatment， the research group was treated by combining traditional Chinese and western medicine treatment， the clinical efficacy of two groups of patients was observed and compared. Results The total effective rate was 74.36% in the control group， 94.87% in the study group， and after treatment， micro-protoplasm and plasma viscosity were （4.56±0.58）g/L （1.26±0.35） mPsa in the control group. The study group of micro-protoplasm and plasma viscosity were （3.25±0.62）g/L and （1.43±0.21） mPsa， respectively. It can be seen that the treatment efficiency of study group patients was significantly higher than the reference group（χ2=6.317 2）， and the study group of patients with hemorheology and urinary albumin-related indicators of the improvement effect was more significant， the difference was statistically significant（P<0.05）. Conclusion The use of integrated traditional Chinese and Western medicine treatment of early diabetic nephropathy， can significantly improve the clinical treatment of patients， while reducing blood viscosity， lipid metabolism regulation， with good protein reduction results， it is worth promoting.

[Key words] Early diabetic nephropathy； Combination of Chinese and western medicine； Hemorheology； Urinary trace albumin

糖尿病腎病作为一种慢性并发症，主要是由于糖尿病引起微血管病变，造成肾小球硬化，其危害性和严重性都比较大，如果没有及时得到有效治疗的话，很有可能会造成患者死亡。早期糖尿病肾病具有一定的隐匿性，但如果在早期就能够及时发现并治疗的话，患者的临床症状就能够得到有效改善，延缓其病情进展，因此在近几年医学界的专家学者都在致力于对早期糖尿病肾病治疗方案的深入研究和探讨，为目的主要是为了找出更加令人满意、更有效的糖尿病肾病治疗手段[1]。……