赵会平

[摘要] 目的 研究分析在寻常普通斑块状银屑病患者中运用复方甘草酸苷胶囊、白芍总苷胶囊、卡泊三醇软膏、窄谱中波紫外线开展联合治疗的临床效果。 方法 从2011年5月—2016年5月期间在该院接受治疗的普通饮血病患者中方便选取280例，将其随机平均分成140例观察组和对照组，首先对两组患者均使用卡泊三醇软膏、窄谱中波紫外线（NB-UVB）以及复方甘草酸苷胶囊进行治疗，之后，对照组在以上基础上服用阿维A胶囊，观察组患者则是服用白芍总苷胶囊。对比两組患者治疗前后的治疗效果、症状积分、症状积分下降指数（SSRI）以及不良反应情况。结果 两组患者治疗后14 d的SSRI分数（0.84±0.38）vs（0.92±0.36）、总体有效率（94.29%）vs（95.00%）均差异无统计学意义（P>0.05），两组患者治疗后28 d的SSRI分数（0.97±0.28）vs（1.02±0.42）、总体有效率（97.86%）VS（97.14%）均差异无统计学意义（P>0.05），在不良反应情况方面，观察组为5.71%，则均显著优于对照组17.86%（P<0.05）。结论 临床上运用白芍总苷胶囊、复方甘草酸苷胶囊口服，联合使用卡泊三醇软膏、窄谱中波紫外线治疗后的效果较好，同时不良反应率较低，具有较高的临床推广价值。

[关键词] 白芍总苷胶囊；复方甘草酸苷胶囊；卡泊三醇软膏；窄谱中波紫外线；银屑病；效果

[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742（2018）01（a）-0114-03

Application of Total Paeoniflorin Capsules， Compound Glycyrrhizin Capsules and Calcipotriol Ointment， Narrow-band UVB in the Treatment of Patients with Psoriasis

ZHAO Hui-ping

Department of Dermatology and Venereology， Affiliated Hospital of Shanxi University of Traditional Chinese Medicine， Taiyuan， Shanxi Province， 030024 China

[Abstract] Objective This paper tries to study the clinical effect of combined use of compound glycyrrhizin capsules， total glucosides of paeoniflorin capsules， carbo triol ointment and narrow-band UVB in the treatment of psoriasis vulgaris. Methods From May 2011 to May 2016， 280 patients were convenient selected from the patients who received the treatment in this hospital. They were randomly divided into 140 observation groups and control group. The patients were divided into two groups： （NB-UVB） and compound glycyrrhizin capsules were treated. After treatment， the control group was treated with acitretin on the basis of the above. The observation group was treated with paeoniflorin capsules. The therapeutic effect， symptom score， symptom score decline index （SSRI） and adverse reaction were compared between the two groups before and after treatment. Results SSRI score （0.84±0.38） vs （0.92±0.36）， total effective rate （94.29%） vs （95.00%） of 14 days after treatment in both groups were not significantly different （P>0.05）. After treatment， the SSRI score of 28 days was （0.97±0.28） vs （1.02±0.42）， the overall response rate （97.86%） vs （97.14%） was not significantly different （P>0.05）， while in the adverse reaction group， the observation group was 5.71 %， significantly better than the control group of 17.86% （P<0.05）. Conclusion The clinical application of total glucosides of paeony capsules and compound glycyrrhizin capsules in combination with carbapenol ointment， narrow spectrum of medium wave ultraviolet radiation after treatment is better， while the low rate of adverse reactions， with a high clinical promotion value.

[Key words] Total paeoniflorin capsules； Compound glycyrrhizin capsules； Kaplatriol ointment； Narrow-spectrum ultraviolet wave； Psoriasis； Effect

银屑病是一类十分顽强且发病率较高的具有免疫炎症特点的皮肤性疾病，到目前为止尚未完全明确此病的发作原理，没有针对性的有效医疗方式，而目前服用药物同时使用紫外线照射（NB- UVB）是当下普遍使用的方式[1]。因为这种疾病十分顽固，而且容易复发，口服单一药品的效果一般不如人意，另外长时间服药容易出现不良反应。所以决定探索效果更好的治疗方式，改进现有治疗方法，让患者更快恢复，减少患者治疗时间。该次……