孙小燕

[摘要] 目的 对比观察常规血液透析与血液透析滤过联合法、高通量血液透析的临床效果。方法 方便选取该院自2016年1月—2017年1月期间收治的56例血液透析患者，采取计算机表法的形式随机分为两组，为参照组（n=28例）与实验组（n=28例），参照组患者予以常规血液透析与血液透析滤过联合法，实验组患者予以高通量血液透析，分析对比两组血液透析患者经CRP、白细胞、收缩压、舒张压、不良反应发生率等情况。结果 参照组血液透析患者CRP、白细胞、收缩压、舒张压、不良反应等指标之间差异无统计学意义（P>0.05）。实验组治疗6个月指标白细胞（6.78±3.22）×109、收缩压（115.54±19.65）mmHg、舒张压（77.24±8.69）mmHg与基线期对比差异有统计学意义（P<0.05）。结论 在维持血液透析过程中常规血液透析与血液透析滤过联合法、高通量血液透析存在类似的疗效，但是高通量血液透析可更好的控制血压，值得应用。

[关键词] 高通量血液透析；常规血液透析；血液透析滤过；效果

[中图分类号] R541 [文献标识码] A [文章编号] 1674-0742（2018）01（a）-0040-03

Comparative Analysis of the Effect of High-throughput Hemodialysis Combined with Routine Hemodialysis

SUN Xiao-yan

Department of Renal Medicine， Chongqing Iron and Steel General Hospital， Chongqing， 400080 China

[Abstract] Objective This paper tries to compare the clinical effects of conventional hemodialysis and hemodiafiltration combined with high flux hemodialysis. Methods 56 hemodialysis patients treated during January 2016 to January 2017 were convenient selected， and were randomly divided into two groups by taking the form of computer table method， as the control group （n=28） and experimental group （n=28）， the control group was treated with routine hemodialysis and hemodiafiltration combined method， experimental group patients with high flux hemodialysis， and the hemodialysis patients were compared between the two groups by CRP， white blood cells， systolic blood pressure and diastolic blood pressure， the incidence of adverse reaction etc. Results There was no significant difference between CRP， leukocyte， systolic blood pressure， diastolic blood pressure and adverse reaction in the hemodialysis patients. The statistical significance was not significant（P>0.05）. The experimental group treated six months index white blood cells were （6.78±3.22）×109， systolic blood pressure （115.54 ± 19.65）mmHg and diastolic blood pressure （77.24±8.69）mmHg， significantly different from those in the baseline group （P<0.05）. The statistical significance was found. Conclusion There are similar efficacy in maintaining hemodialysis during routine hemodialysis and hemodiafiltration combined method， high flux hemodialysis， blood pressure control， but high flux hemodialysis can be better， it is worthy of application

[Key words] High flux hemodialysis； Routine hemodialysis； Hemodiafiltration； Effect

血液透析是清除大分子毒素的一種有效措施，血液透析是临床治疗慢性肾脏疾病终末期肾衰竭的关键措施[1-2]，可将尿毒症毒素有效清除，维持体内酸碱与水电解质平衡，但是也存在很多不良反应，因此需要各界人士高度重视。现将该院2016年1月—2017年1月期间收治的56例血液透析患者分析结果予以报道，现报道如下。

1 资料与方法

1.1 一般资料

该次方便选取该院收治的56例血液透析患者作为样本数据，以计算机表法对患者予以组别均分，每组例数为28例，参照组患者中女性患者例数14例，男性患者例数14例，最大年龄76岁，最小年龄20岁，中位年龄（45.32±5.65）岁，最长透析时间13年，最短透析时间0.5年，中位透析时间（6.25±1.32）年；实……