68例轻型进展性脑梗死相关危险因素分析
2018-01-21刘瑜代萌王星宋金辉
刘瑜 代萌 王星 宋金辉
【摘要】目的 讨论与轻型脑梗死进展相关的危险因素。方法 选取我院2015年7月~2018年7月在我院住院治疗、确诊为轻型急性脑梗死患者。根据美国国立卫生研究院卒中量表(national institute of health stroke scale,NIHSS)进行评分,评分≤3分。根据发病后神经系统缺损症状有没有加重进行分组,观察组68例为轻型进展性脑梗死,对照组72例为轻型稳定性脑梗死。回顾性分析比较两组患者既往病史、不良嗜好、本次住院时的检查及化验结果。结果 观察组中过度降压、合并有糖尿病、高尿酸血症的比例明显高于对照组,差异有统计学意义(P<0.05)。结论 过度降压、既往有糖尿病史、高尿酸血症与轻型进展性脑梗死相关,差异有统计学意义(P<0.05);既往有高血压病、冠心病、慢性心衰病史,存在颈动脉斑块、高同型半胱氨酸血症,存在不良嗜好吸烟、酗酒,一般情况中的年龄、性别与轻型脑梗死的进展比较;差异无统计学意义(P>0.05)。
【关键词】进展性脑梗死;稳定性脑梗死;危险因素
【中图分类号】R743 【文献标识码】A 【文章编号】ISSN.2095.6681.2018.32..02
【Abstract】Objective To Risk factors related to the progression of mild cerebral infarction were discussed.Methods All subjects were hospitalized in our hospital from July 2015 to July 2018, and were diagnosed as mild acute cerebral infarction. According to the National Institutes of Health Stroke Scale (NIHSS),the score was less than 3.According to the aggravation of nervous system defect symptoms,68 cases in the observation group were mild progressive cerebral infarction,72 cases in the control group were mild stable cerebral infarction.A retrospective analysis and comparison of the two groups of patients with medical history,bad habits, this hospital examination and laboratory results.Results The proportion of hypertensive, diabetes mellitus and hyperuricemia in the observation group was significantly higher than that in the control group (P<0.05).Conclusion Hypertension,diabetes mellitus and hyperuricemia were associated with mild progressive cerebral infarction (P<0.05).History of hypertension, coronary heart disease,chronic heart failure, carotid plaques,hyperhomocysteinemia, bad habits of smoking and alcohol abuse, age and sex was not significantly correlated with the progression of cerebral infarction (P>0.05).
【Key words】The progression of cerebral infarction;Stable cerebral infarction;Risk factors
進展性脑梗死是指脑梗死发病6小时后患者的神经系统功能缺损进行性加重[1],其病情的进展可持续至数天后,据报道,其发病率约占全部脑梗死的26%~43%[2],对患者造成了很大的危害。为了对进展性脑梗死有更早的预测及干预,我们回顾性地分析了诊断明确的、在我科住院治疗的140例轻型脑梗死患者的有关临床资料,现报告如下。
1 资料与方法
1.1 一般资料
选取我院2015年7月~2018年7月住院治疗的急性脑梗死患者140例,所有患者均符合急性脑梗死诊断标准[3],且NIHSS评分≤3分。排除标准:NIHSS评分>3分者,TIA、心源性脑栓塞、脑肿瘤、中枢神经系统免疫性及感染性疾病、严重的意识障碍、有明确的感染病灶所致高热、严重营养不良恶液质、消化道出血、近期做过大手术的患者。观察组68例为进展性脑梗死,发病72小时内NIHSS评分增加≥2分[4]为诊断标准,其中男39例,女29例,平均年龄66.7岁。……
