陈爱华　翟爱琴

[摘要] 目的 探究保妇康栓联合酮康唑治疗阴道炎合并糖尿病的临床效果。 方法 将2015年3月—2017年3月南京市浦口区浦厂医院收治的140例阴道炎合并糖尿病患者随机分为对照组和观察组，对照组给予酮康唑软膏，观察组同时联合保妇康栓治疗，比较两组患者的临床治疗效果。结果 对照组治疗总有效率为77.14%，观察组为94.29%；观察组阴道状况改善程度明显优于对照组；其阴道疼痛、灼热、黏膜出血、瘙痒、白带增多发生率均较低；治疗后生活质量各影响因子评分均高于对照组（P<0.05）；两组不良反应发生率比较差异无统计学意义（P>0.05）。结论 保妇康栓联合酮康唑治疗阴道炎合并糖尿病安全有效，值得临床推广。

[关键词] 保妇康栓；酮康唑；阴道炎；糖尿病；临床疗效

[中图分类号] R587.1 [文献标识码] A [文章编号] 1672-4062（2017）07（b）-0024-03

Study on Clinical Effect of Baofukang Suppository and Ketoconazole in Treatment of Colpitis and Diabetes

CHEN Ai-hua1， ZHAI Ai-qin2

1.Puchang Hospital of Pukou District， Nanjing， Jiangsu Province， 210031 China；2.Pukou Hospital， Nanjing， Jiangsu Province， 210009 China

[Abstract] Objective To study the clinical effect of Baofukang suppository and ketoconazole in treatment of colpitis and diabetes. Methods 140 cases of patients with colpitis and diabetes treated in Puchang hospotal Pukou Didestrict from March 2015 to March 2017 were randomly divided into two groups， the control group were treated with ketoconazole ointment， while the observation group were treated with ketoconazole ointment and baofukang suppository， and the clinical treatment effect was compared between the two groups. Results The total effective rate in the control group and in the observation group was respectively 77.14% and 94.29%， and the improvement degree of vaginal status in the observation group was obviously better than that in the control group， and the incidence rate of vaginal pain， burning， mucous membrane bleeding， itching and leucorrhea increase was lower， and various influence factors scores of quality of life after treatment were higher than those in the control group（P<0.05）， and there was no obvious difference in the incidence rate of adverse reaction between the two groups（P>0.05）. Conclusion The baofukang suppository and ketoconazole in treatment of colpitis and diabetes is safe and effective， which is worth clinical promotion.

[Key words] Baofukang suppository； Ketoconazole； Colpitis； Diabetes； Clinical curative effect

阴道炎是一种发病率较高的妇科疾病，临床症状复杂，严重影响患者生活质量[1]。临床观察研究显示，高龄及糖尿病是阴道炎的危险因素，常造成病情的反复发作，提高了临床治疗难度[2]。虽然目前的药物及疗法均有一定疗效，但效果存在差异[3]。为了更有效地治疗阴道炎合并糖尿病，该文以该院2015年3月—2017年3月收治的阴道炎合并糖尿病患者為研究对象，研究保妇康栓联合酮康唑的临床效果，现报道如下。

1 资料与方法

1.1 一般资料

将该院收治的140例阴道炎合并糖尿病患者随机分为对照组和观察组，各70例。纳入标准：①糖尿病病情可控；②阴道炎是由巨细胞病毒、人类免疫缺陷病毒、疱疹病毒等病毒感染引起的，未发现酵母菌以及滴虫；……