洗鼻法配合糠酸莫米松与氯雷他定治疗过敏性鼻炎的疗效观察

2017-10-18韩星星周红艳

陇东学院学报 2017年5期

关键词：症状

韩星星，周红艳

(1.陇东学院岐伯医学院，甘肃庆阳 745000；2.庆阳市人民医院，甘肃庆阳 745000)

洗鼻法配合糠酸莫米松与氯雷他定治疗过敏性鼻炎的疗效观察

韩星星1，周红艳2

(1.陇东学院岐伯医学院，甘肃庆阳 745000；2.庆阳市人民医院，甘肃庆阳 745000)

目的：观察洗鼻法配合糠酸莫米松与氯雷他定治疗过敏性鼻炎的临床疗效。方法：选取庆阳市人民医院门诊收治的100名过敏性鼻炎患者依据不同的治疗方案随机分为对照组和观察组，坚持治疗8周，分析两组患者的总体疗效及鼻炎症状评分、不良反应发生率和停药后3个月内的复发率。结果：观察组总有效率高于对照组，两者比较差异有统计学意义(P<0.05)；观察组鼻炎症状及TNSS评分低于对照组,差异有统计学意义(P<0.05)；2组药物不良反应比较，差异无统计学意义(P>0.05)；停药后，观察组过敏性鼻炎复发率低于对照组,两者比较差异有统计学意义(P<0.05)。结论：洗鼻法配合糠酸莫米松与氯雷他定治疗过敏性鼻炎，可以有效改善患者鼻炎症状，总体疗效高且复发率低，值得临床推广。

洗鼻法；糠酸莫米松；过敏性鼻炎；疗效观察

Abstract： Objective: To observe clinical effects of allergic rhinitis treated with nasal washing with mometasone furoate and loratadine.Method: collect 100 cases of allergic rhinitis in Qingyang municipal hospital’s outpatient department,which were divided randomly into control group and observation group according to different planning treatments.Hold the treatment in 8 weeks,and then analyze sufferers in 2 groups about general efficacy,symptom score,the ADR rate and recurrence rate in following 3 mouths.Result: Effective rate in control group is higher than observation group,comparative difference has statistical significance(P<0.05);Symptom score and TNSS in control group is lower,and the difference has significance(P<0.05);The ADR rate in 2 has no significance(P>0.05);After treatment,recurrence rate in control group is lower,and the difference has significance(P<0.05).Conclusion: This treatment has effective improvement for allergic rhinitis sufferers.The general efficacy is higher with lower recurrence which deserves clinical expansion.

Keywords： nasal washing;mometasone furoate;allergic rhinitis;curative effect observation

过敏性鼻炎为临床常见变态反应性疾病，具有就诊率低、发病机制复杂、病程长、易复发等特点，严重影响患者的身心健康和生活质量。有数据显示：过敏性鼻炎在我国的发病率为10%～30%，并呈逐年上升趋势[1]。临床治疗过敏性鼻炎，一般首选糖皮质激素和抗组胺药物，单独或联合使用，效果不明显且副作用较大[2]。本研究在以上两类药物联合使用的基础上配以生理盐水洗鼻，取得了满意的临床疗效，现报道如下。