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临床药师参与1例重症胰腺炎患者营养支持的案例分析

2017-10-10刘红孙旭群杨旭汪燕燕夏泉

上海医药 2017年17期

刘红+孙旭群+杨旭+汪燕燕+夏泉

摘 要 目的: 探讨临床药师在重症急性胰腺炎患者个体化营养支持治疗中的作用。方法: 通过1例重症急性胰腺炎案例,分析患者肠内营养不耐受的原因并采取相应对策,结合患者病理生理特点制定个体化肠外营养支持方案。结果与结论: 临床药师应对重症急性胰腺炎患者的营养支持开展全程化的药学监护,及时调整营养支持方式,调节患者营养状态,改善患者预后。

关键词 临床药师 重症急性胰腺炎 营养治疗

中图分类号:R576 文献标识码:C 文章编号:1006-1533(2017)17-0065-04

Clinical pharmacists participate a case analysis of nutrition support therapy for a patient with severe acute pancreatitis

LIU Hong*, SUN Xuqun, YANG Xu, WANG Yanyan, XIA Quan**

(Department of Pharmacy, the first Hospital affiliated to Anhui Medical University, Hefei 230061, China)

ABSTRACT Objective: To explore the role of clinical pha=rmacists in individual nutrition support therapy for severe acute pancreatitis patients. Methods: A case of clinical nutritional therapy for a severe acute pancreatitis patient who had intolerance with enteral nutrition was analyzed and individualized nutritional therapy was applied based on pathophysiologic characteristic. Results & Conclusion: Pharmaceutical care of clinical nutrition therapy for a severe acute pancreatitis patient was carried out by clinical pharmacists in the whole process. Patient prognosis was improved by timely adjustment of nutritional support and nutritional status of patient.

KEy WORDS clinical pharmacist; severe acute pancreatitis; nutrition support therapy

重症急性胰腺炎(severe acute pancreatitis,SAP)是多种原因引起的胰酶激活而导致的胰腺局部严重炎性反应[1-2]。重症胰腺炎患者可出现营养不良,同时伴有糖、脂、蛋白代谢异常。有效的营养支持可纠正患者由于高分解、高代谢而出现的负氮平衡,维持肠黏膜屏障功能的完整性,明显减少肠源性感染的发生[3]。临床药师对于1例SAP患者营养支持方式的转换及个体化营养处方的制定提出药学建议,现报告如下。

1 病歷摘要

患者男性,60岁。因“中上腹疼痛伴呕吐1周”入院。1周前,患者大量饮酒后出现中上腹胀疼痛不适同时伴有腰背部疼痛,疼痛剧烈时伴有呕吐。外院查血淀粉酶882 U/L;血钙 1.56 mmol/L。诊断为急性胰腺炎给予奥美拉唑、生长抑素、左氧氟沙星注射液等对症治疗后无明显好转,遂于2016年10月22日转入我院。发病以来精神睡眠差,小便减少,大便未解,不能进食。既往有慢性胆囊炎病史8年;2型糖尿病病史3年,一直未予治疗;……

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