李青先

DOI：10.16662/j.cnki.1674-0742.2017.09.172

[摘要] 目的 研究红藤汤治疗慢性盆腔炎后血液流变学及相关炎性因子变化，以阐述临床疗效。 方法 回顾性分析该院妇科2015年12月—2016年11月收治的慢性盆腔炎患者168例病历资料，观察组87例常规治疗的基础上辅以红藤汤治疗，对照组81例给予常规治疗。观察两组患者血液流变学和血浆炎症因子IL-6和TNF-α水平的变化，并对治疗效果进行评价。结果 经治疗4周后，观察组不同切变速率下的全血黏度为（9.22±0.16）、（5.67±0.36）、（4.17±0.54）mPa·s，IL-6和TNF-α水平分别为（19.48±4.71）pg/mL和（89.51±17.95）pg/mL，均显著低于对照组，差异有统计学意义（P<0.05）。经治疗观察组总有效率为94.25%，对照组总有效率为75.31%。观察组总有效率显著高于对照组，差异有统计学意义（χ2=3.354，P<0.05）。结论 红藤汤治疗慢性盆腔炎疗效显著。

[关键词] 红藤汤；慢性盆腔炎；炎性因子；血液流变学

[中图分类号] R4 [文献标识码] A [文章编号] 1674-0742（2017）03（c）-0172-03

Research on Sargentglory Decoction on the Pelvic Inflammatory Disease Related Inflammatory Factors and Clinical Curative Effect

LI Qing-xian

Department of Gynecology and Obstetrics， Putuo District Central Hospital， Shanghai， 200062 China

[Abstract] Objective To research the hemorheology and related inflammatory factors changes after the sargentglory decoction in treatment of chronic pelvic inflammatory disease. Methods 168 cases of patients with chronic pelvic inflammatory disease admitted and treated in our hospital from December 2015 to November 2016 were retrospectively analyzed and divided into two groups， the control group with 87 cases were treated with sargentglory decoction on the basis of the routine treatment， while the control group with 81 cases adopted the routine treatment， and the changes of hemorheology and plasma inflammatory factors IL-6 and TNF-αlevels of the two groups were observed and the treatment effect was evaluated. Results After four-week treatment， the whole blood viscosity at different shear rates， IL-6 and TNF-α levels were respectively （9.22±0.16），（5.67±0.36），（4.17±0.54）mPa·s，（19.48±4.71）pg/mL and（89.51±17.95）pg/mL， which were obviously lower than that in the control group， and the differences between groups were statistically significant（P<0.05）， after treatment， the total effective rate in the observation group was obviously higher than that in the control group（94.25% vs 75.31%）， and the difference was statistically significant （χ2=3.354，P<0.05）. Conclusion The curative effect of sargentglory decoction in treatment of the chronic pelvic inflammatory disease is obvious.

[Key words] Sargentglory decoction； Chronic pelvic inflammatory disease； Inflammatory factor； Hemorheology

盆腔炎性疾病（ pelvic inflammatory disease，PID） 是指淋病奈瑟菌、衣原體等生殖道常见病原菌感染女性上生殖道后引起的盆腔器官及其周围组织的炎症性疾病。临床常见有盆腔腹膜炎、子宫内膜炎、输卵管卵巢脓肿和输卵管炎等，是临床妇科常见的生殖系炎性疾病[1-2]。PID好发于性活跃期的女性，随着社会的发展和人们生活方式的改变，PID的发病率不断攀升，PID反复发作，性激素水平长期处于异常状态，导致痛经、不孕不育等病证，引甚则起生殖系器质性病变，严重影响患者的生存质量[3]。该次研究方便选取该院妇科2015年12月—2016年11月收治的慢性盆腔炎患者168例的病历资料进行回顾性分析，探讨常规治疗的基础上辅以红藤汤治疗慢性盆腔炎的临床疗效，现报道如下。……