倪浩++周建岭++刘丹丹

DOI：10.16662/j.cnki.1674-0742.2017.09.099

[摘要] 目的 研究分析原發性高压应用厄贝沙坦联合左旋氨氯地平的临床治疗效果。方法 随机选取该院2013年9月—2016年9月期间收治的原发性高血压患者60例，根据随机数字表法将患者进行随机分组，对照组和观察组各30例。照组给予厄贝沙坦，观察组给予厄贝沙坦联合苯磺酸左旋氨氯地平，患者治疗1个月。 结果 观察组的总有效率为93.3%高于对照组的总有效率70.0%，组间数据差异有统计学意义（P<0.05）；治疗前观察组和对照组患者的收缩压和舒张压进行比较，组间差异无统计学意义（P>0.05）；治疗后观察组和对照组患者收缩压和舒张压均明显下降，与治疗前比较差异有统计学意义（P<0.05）；观察组患者的舒张压（80.3±5.8）mmHg和收缩压（120.7±8.1）mmHg下降程度明显高于对照组患者血压指标，差异有统计学意义（P<0.05）；观察组的不良反应率明显低于对照组患者，差异有统计学意义（P<0.05）。结论 苯磺酸左旋氨氯地平联合而被沙坦治疗原发性高血压安全有效值得在临床应用。

[关键词] 厄贝沙坦；左旋氨氯地平；原发性高血压；临床效果

[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742（2017）03（c）-0099-03

Research on Feasibility of Irbesartan and Levaml Odipine Besylate Tablets in Treatment of Primary Hypertension

NI Hao， ZHOU Jian-ling， LIU Dan-dan

Department of Cardiology， Lianyungang Donghai Peoples Hospital， Lianyungang， Jiangsu Province， 222300 China

[Abstract] Objective To research and analyze the clinical effect of irbesartan and levaml odipine besylate tablets in treatment of primary hypertension. Methods 60 cases of patients with primary hypertension admitted and treated in our hospital from September 2013 to September 2016 were random selected and randomly divided into two groups with 30 cases in each， the control group were given the irbesartan， while the observation group were given the irbesartan and levaml odipine besylate tablets， and the patients were treated for one month. Results The total effective rate in the observation group was higher than that in the control group（93.3% vs 70.0%）， and the difference was obvious（P<0.05）， before treatment， the differences in the systolic blood pressure and diastolic blood pressure between the two groups were not statistically significant（P>0.05）， after treatment， the systolic blood pressure and diastolic blood pressure of the two groups obviously decreased， and the differences were statistically significant compared with those before treatment（P<0.05）， and the decrease degree of systolic blood pressure and diastolic blood pressure was obviously higher than that in the control group， which was respectively（80.3±5.8）mmHg and（120.7±8.1）mmHg， and the differences were statistically significant（P<0.05）， and the adverse reaction rate in the observation group was obviously lower than that in the control group， and the difference was statistically significant（P<0.05）. Conclusion The irbesartan and levaml odipine besylate tablets in treatment of primary hypertension is safe and effective， which is worth clinical application.

[Key words] Irbesartan； Levaml odipine besylate tablets； Primary hypertension； Clinical effect

高血压是临床中较常见的心血管疾病，临床表现为体循环动脉压异常升高，类型分为原发性高血压和继发性高血压[1-2]。对于高血压的治疗提供平稳的降压方式是高血压患者健康生活的关键[3]。该次研究2013年9月—2016年9月对该院收治60例原发性高血压患者采用厄贝沙坦联合左旋氨氯地平治疗，观察患者的临床效果，现报道如下。……