高平江苏省阜宁县人民医院妇产科，江苏阜宁　224400

LEEP刀治疗宫颈上皮内瘤样病变临床分析

高平
江苏省阜宁县人民医院妇产科，江苏阜宁224400

目的对宫颈上皮内瘤样病变应用LEEP刀治疗的临床效果进行分析研究。方法选取于2013年2月—2016年2月期间在该院接受治疗的宫颈上皮内瘤样病变患者56例，并1：1随机分为参照组和实验组各28例，分别应用冷刀宫颈锥切术和LEEP刀治疗，观察并对比两组患者的手术时间、排液时间、术中出血量等指标。结果 实验组患者的手术时间为（10.92±2.16）min，术中出血量为（12.66±3.33）mL，排液时间为（8.03±1.57）d，切口愈合时间为（35.22±3.66）d；参照组患者的手术时间为（24.58±5.39）min，术中出血量为（47.77±10.44）mL，排液时间为（15.91±2.89）d，切口愈合时间为（45.55±11.55）d。实验组患者的各项指标改善均优于参照组，差异有统计学意义（P＜0.05）；实验组术后并发症发生率明显低于参照组（11.11%VS 33.33%）；宫颈塑性满意率、手术治愈率均明显高于参照组（94.44%、94.44%VS 72.22%、77.78%），组间差异经t检验，差异有统计学意义（P＜0.05）。结论宫颈上皮内瘤样病变应用LEEP刀治疗的临床效果十分理想，值得大力推广。

LEEP刀；宫颈上皮内瘤样病变；宫颈癌

［Abstract］Objective The clinical effects of cervical intraepithelial neoplasia application LEEP knife treatment were analyzed.Methods From February 2013—February 2016 in patients with tumor-like lesions in the hospital for treatment of cervical intraepithelial 56 cases，and 1：1 and the reference group were randomly divided into the experimental group，28 cases were applied cold knife conization and LEEP knife treatment，the two groups were observed and compared operative time，drainage time，blood loss and other indicators.Results The experimental group operation time was （10.92±2.16）min，blood loss was（12.66±3.33）mL，the discharge time was（8.03±1.57）d，wound healing time was （35.22±3.66）d；reference group of patients with operation time was（24.58±5.39）min，blood loss was（47.77±10.44）mL，the discharge time was（15.91±2.89）d，wound healing time was（45.55±11.55）d.The indicators improved experimental group were better than the reference group，the difference was statistically significant（P＜0.05）；postoperative complications in the experimental group was significantly lower than the reference group（11.11%VS 33.33%）；Cervical plastic satisfaction rate，the cure rate was significantly higher than the reference group（94.44%，94.44%VS 72.22%，77.78%），the difference between the two groups by t test，was statistically significant（P＜0.05）.Conclusion Cervical intraepithelial neoplasia application LEEP knife treatment clinical results are quite satisfactory，it is worth promoting.

［Key words］LEEP knife；Cervical intraepithelial neoplasia；Cervical cancer

宫颈癌这种临床常见恶性肿瘤的发病率近年来呈现出大幅度上升的增长趋势并且发病年龄呈现出年轻化趋势［1］。宫颈上皮内瘤样病变包括两种类型，分别是宫颈不典型增生及宫颈原位癌，这两种病变均属于宫颈浸润癌的癌前病变，因此需要早期采取有效措施，来使宫颈癌发病率明显降低［2］。该院将LEEP刀应用于2013年2月—2016年2月期间收治的宫颈上皮内瘤样病变36例患者中，安全有效，现报道如下。……