张欢庆，董　辉，周艳丽，冶保献，徐茂田,

(1. 郑州大学 化学与分子工程学院，河南 郑州 450001；　2. 商丘师范学院 化学化工学院，河南 商丘 476000)



基于联萘酚衍生物的荧光传感器对Ca2+的选择性测定

张欢庆1，董辉1，周艳丽2*，冶保献1，徐茂田1,2*

(1. 郑州大学 化学与分子工程学院，河南 郑州 450001；2. 商丘师范学院 化学化工学院，河南 商丘 476000)

摘要：设计了基于联萘酚衍生物(LZ)的高选择性的荧光化学传感器,分别采用荧光光谱和紫外-可见光谱法研究了其对Ca2+的识别.结果显示,与其他金属离子,如Ag+、Al3+、Bi3+、Cd2+、Co3+、Cr3+、Cu2+、Fe3+、Hg2+、K+、Mg2+、Mn2+、Ni2+、Pb2+、Zn2+相比,探针LZ对Ca2+呈现良好的选择性.并且该探针在486 nm处的荧光强度与Ca2+浓度在2~7 μmol/L范围内呈现良好的线性关系,其回归系数为0.994,检测限为0.8 μmol/L,多次测定的相对标准偏差为2%.

关键词：联萘酚衍生物;荧光化学传感器;Ca2+

The selective detection of Ca2+based on binaphthol derivatives

fluorescent chemosensor

ZHANG Huanqing1, DONG Hui1, ZHOU Yanli2*, YE Baoxian1, XU Maotian1,2*

(1.CollegeofChemistryandMolecularEngineering,ZhengzhouUniversity,Zhengzhou450001,Henan,China;

2.CollegeofChemistryandChemicalEngineering,ShangqiuNormalUniversity,Shangqiu476000,Henan,China)

Abstract:A fluorescent chemosensor based on binaphthol derivatives was fabricated. The Ca2+recognition was studied by fluorescent and UV-Vis spectra by the use of fluorescent probe. The results showed that the probe displayed a good selectivity of Ca2 +, comprared with other metal ions , such as Ag+, Al3+, Bi3+, Cd2+, Co3+, Cr3+, Cu2+, Fe3+, Hg2+, K+, Mg2+, Mn2+, Ni2+, Pb2+and Zn2+. The fluorescence intensity of the probe at 486 nm with the Ca2+concentration showed a good linear relationship in the range of 2-7 μmol/L with a correlation coefficient of 0.994, a detection limit of 0.8 μmol/L and a relative deviation of 2%. In this work, one-dimensional (1D) cobalt nanostructures were prepared via the facile reduction of Co2+ions under atmospheric pressure. The morphology change after the grinding of the 1D sample cobalt nanostructures was also investigated. Results reveal that the external magnetic field promotes the preferred orientation of Co nanostructures and the obtained 1D nanostructure retains a large aspect ratio after it is fully ground. Moreover, the Co nanostructures obtained with an external magnetic field exhibits a better electromagnetic wave absorbance.

Keywords:binaphthol derivatives; fluorescent chemosensor; Ca2+cobalt; magnetic materials; crystal growth; external magnetic field; electromagnetic properties

Ca2+是人体内最常见的阳离子,作为通用的细胞内信使,主要用于骨骼的组成[1].游离的Ca2+在细胞中起着重要的协调作用[2],其浓度的失衡是细胞凋亡[3]的中心环节，因此准确测定细胞内Ca2+浓度的变化[4]对揭示细胞的生命过程至关重要.目前Ca2+的测定方法主要有原子吸收光谱法[5]、选择性微电极法[6]、电子显微镜法、放射示踪法、毛细管电泳-电感耦合等离子体发射光谱法[7]等，但是这些方法存在仪器昂贵、操作复杂和精密度较差等缺陷,故寻找一种快速而灵敏的检测Ca2+的方法具有重要的意义.

联萘酚及其衍生物[8]具有C2不对称、π共轭、能够扭转的非平面及非常稳定的手形结构,而且优势位点较多.近年来它被广泛应用于分……